Tylosin

Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Tylosin?

Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Tylosin

PubChem Associated disorders and diseases

What pathways are associated with Tylosin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Tylosin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Tylosin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Tylosin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Tylosin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Tylosin?

Knock-out

Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Tylosin

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Authors Title Published Journal PubMed Link
De Mil T et al. Influence of mycotoxin binders on the oral bioavailability of tylosin, doxycycline, diclazuril, and salinomycin in fed broiler chickens. 2017 Poult. Sci. pmid:28160001
Poole TL et al. Competitive exclusion of a glycopeptide-resistant Enterococcus faecium in the presence of vancomycin but not equivalent concentrations of tylosin or gentamicin. 2004 Poult. Sci. pmid:15285499
Vandenberge V et al. Transfer of flubendazole and tylosin from feed at cross-contamination levels to various poultry matrices. 2012 Poult. Sci. pmid:22912473
Dafwang II et al. Broiler chick growth response to antibiotics, 1981-1982. 1984 Poult. Sci. pmid:6610176
Vandenberge V et al. Transfer of flubendazole and tylosin at cross contamination levels in the feed to egg matrices and distribution between egg yolk and egg white. 2012 Poult. Sci. pmid:22499885
Garcés-Narro C et al. Efficacy of low-dose tylvalosin for the control of clostridiosis in broilers and its effect on productive parameters. 2013 Poult. Sci. pmid:23472021
Khalifeh MS et al. Assessment of humoral and cellular-mediated immune response in chickens treated with tilmicosin, florfenicol, or enrofloxacin at the time of Newcastle disease vaccination. 2009 Poult. Sci. pmid:19762865
Scorneaux B and Shryock TR Intracellular accumulation, subcellular distribution, and efflux of tilmicosin in chicken phagocytes. 1998 Poult. Sci. pmid:9776059
Baba T et al. Effect of tylosin tartrate (Tylan Soluble) on cellular immune responses in chickens. 1998 Poult. Sci. pmid:9733118
Berrang ME et al. Subtherapeutic tylosin phosphate in broiler feed affects Campylobacter on carcasses during processing. 2007 Poult. Sci. pmid:17495097
Kowalski C et al. Pharmacokinetics of tylosin in broiler chickens. 2002 Pol J Vet Sci pmid:12448074
Krongdang S et al. Multilocus sequence typing, biochemical and antibiotic resistance characterizations reveal diversity of North American strains of the honey bee pathogen Paenibacillus larvae. 2017 PLoS ONE pmid:28467471
Zhang N et al. Determination of the Mutant Selection Window and Evaluation of the Killing of Mycoplasma gallisepticum by Danofloxacin, Doxycycline, Tilmicosin, Tylvalosin and Valnemulin. 2017 PLoS ONE pmid:28052123
Galmozzi CV et al. The Cyanobacterial Ribosomal-Associated Protein LrtA Is Involved in Post-Stress Survival in Synechocystis sp. PCC 6803. 2016 PLoS ONE pmid:27442126
Danzeisen JL et al. Modulations of the chicken cecal microbiome and metagenome in response to anticoccidial and growth promoter treatment. 2011 PLoS ONE pmid:22114729
Menozzi A et al. Effect of the macrolide antibacterial drug, tylosin, on TNBS-induced colitis in the rat. 2005 Pharmacology pmid:15756055
Meisel ML et al. Effects of tylosin on the pituitary-gonadal axis in male rats. 1993 Apr-May Pharmacol. Toxicol. pmid:8372057
Muraina IA et al. Antimycoplasmal activity of some plant species from northern Nigeria compared to the currently used therapeutic agent. 2010 Pharm Biol pmid:20819025
Kempf I et al. [Efficacy of spiramycin and tylosin in preventing mycoplasmosis in chicks experimentally infected with mycoplasma gallisepticum]. 1989 Pathol. Biol. pmid:2797880
Xie S et al. Acute toxicity study of tilmicosin-loaded hydrogenated castor oil-solid lipid nanoparticles. 2011 Part Fibre Toxicol pmid:22098626