| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Diarrhea | D003967 | 32 associated lipids |
| Bacterial Infections | D001424 | 21 associated lipids |
| Colitis | D003092 | 69 associated lipids |
| Cattle Diseases | D002418 | 24 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Facial Dermatoses | D005148 | 7 associated lipids |
| Occupational Diseases | D009784 | 42 associated lipids |
| Asthma | D001249 | 52 associated lipids |
| Weight Gain | D015430 | 101 associated lipids |
| Foreign Bodies | D005547 | 5 associated lipids |
| Hyperplasia | D006965 | 34 associated lipids |
| Clostridium Infections | D003015 | 5 associated lipids |
| Ataxia | D001259 | 20 associated lipids |
| Staphylococcal Skin Infections | D013207 | 9 associated lipids |
| Bacteriuria | D001437 | 7 associated lipids |
| Pasteurella Infections | D010326 | 8 associated lipids |
| Swine Diseases | D013553 | 16 associated lipids |
| Poultry Diseases | D011201 | 21 associated lipids |
| Vasculitis | D014657 | 14 associated lipids |
Tylosin
Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Tylosin?
Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (6)
- Proc. Natl. Acad. Sci. U.S.A. (2)
- Appl. Environ. Microbiol. (2)
- Others (6)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Tylosin
PubChem Associated disorders and diseases
What pathways are associated with Tylosin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Tylosin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Tylosin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Tylosin?
There are no associated biomedical information in the current reference collection.
What genes are associated with Tylosin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (9)
- Microbiology (Reading, Engl.) (3)
- FEMS Microbiol. Lett. (2)
- Others (13)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Tylosin?
Knock-out
Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with Tylosin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Liu YM et al. | Sensitive determination of tilmicosin, erythromycin ethylsuccinate and clindamycin by CE with electrochemiluminescence detection using azithromycin as internal standard and its applications. | 2010 | J Sep Sci | pmid:20235137 |
| Catania S et al. | Treatment of eggshell abnormalities and reduced egg production caused by Mycoplasma synoviae infection. | 2010 | Avian Dis. | pmid:20608549 |
| Alatrache A et al. | Tylosin abatement in water by photocatalytic process. | 2010 | Water Sci. Technol. | pmid:20651450 |
| Kaizerman JA et al. | Addressing PXR liabilities of phthalazine-based hedgehog/smoothened antagonists using novel pyridopyridazines. | 2010 | Bioorg. Med. Chem. Lett. | pmid:20594845 |
| Peltier E et al. | Zinc-induced antibiotic resistance in activated sludge bioreactors. | 2010 | Water Res. | pmid:20537675 |
| Barbour EK et al. | Impact of synergism of calcium phosphomycin/tylosin tartarate supplements on the performance of broilers in the Lebanon. | 2010 Jan-Mar | Vet. Ital. | pmid:20391366 |
| Sumbatian NV et al. | [Amino acid and peptide derivatives of the tylosin family of macrolide antibiotics modified at the aldehyde group]. | 2010 Mar-Apr | Bioorg. Khim. | pmid:20531486 |
| Reynaldi FJ et al. | [Binding of tylosin, tilmicosin and oxytetracycline to proteins from honeybees, larvae and beehive products]. | 2010 Oct-Dec | Rev. Argent. Microbiol. | pmid:21229198 |
| Shimada T et al. | Effects of the antimicrobial tylosin on the microbial community structure of an anaerobic sequencing batch reactor. | 2011 | Biotechnol. Bioeng. | pmid:20830676 |
| Kim EY et al. | Pharmacokinetics of a florfenicol-tylosin combination after intravenous and intramuscular administration to beagle dogs. | 2011 | J. Vet. Med. Sci. | pmid:21068517 |
| Bosi P et al. | Feed supplemented with 3 different antibiotics improved food intake and decreased the activation of the humoral immune response in healthy weaned pigs but had differing effects on intestinal microbiota. | 2011 | J. Anim. Sci. | pmid:21724943 |
| Park JW et al. | Generation of reduced macrolide analogs by regio-specific biotransformation. | 2011 | J. Antibiot. | pmid:21102594 |
| Ci X et al. | Anti-inflammatory effects of tilmicosin in a noninfectious mouse model of allergic asthma. | 2011 | Immunopharmacol Immunotoxicol | pmid:21428709 |
| Zheng Y et al. | Molecularly imprinted solid-phase extraction for determination of tilmicosin in feed using high performance liquid chromatography. | 2011 | Anal. Chim. Acta | pmid:21435486 |
| Kalmokoff M et al. | Continuous feeding of antimicrobial growth promoters to commercial swine during the growing/finishing phase does not modify faecal community erythromycin resistance or community structure. | 2011 | J. Appl. Microbiol. | pmid:21395944 |
| Juntunen P et al. | Longitudinal on-farm study of the development of antimicrobial resistance in Campylobacter coli from pigs before and after danofloxacin and tylosin treatments. | 2011 | Vet. Microbiol. | pmid:21397412 |
| Cooprider KL et al. | Feedlot efficiency implications on greenhouse gas emissions and sustainability. | 2011 | J. Anim. Sci. | pmid:21398565 |
| Bernal J et al. | Determination of tylosins A, B, C and D in bee larvae by liquid chromatography coupled to ion trap-tandem mass spectrometry. | 2011 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:21498134 |
| Smee NM and Towell TL | What is the evidence? Inflammatory bowel disease in a dog. | 2011 | J. Am. Vet. Med. Assoc. | pmid:21529230 |
| Kilpinen S et al. | Effect of tylosin on dogs with suspected tylosin-responsive diarrhea: a placebo-controlled, randomized, double-blinded, prospective clinical trial. | 2011 | Acta Vet. Scand. | pmid:21489311 |
| Alexander TW et al. | Longitudinal characterization of antimicrobial resistance genes in feces shed from cattle fed different subtherapeutic antibiotics. | 2011 | BMC Microbiol. | pmid:21261985 |
| Ozaki H et al. | Antimicrobial resistance in fecal Escherichia coli isolated from growing chickens on commercial broiler farms. | 2011 | Vet. Microbiol. | pmid:21232883 |
| Song M et al. | The controlled release of tilmicosin from silica nanoparticles. | 2011 | Drug Dev Ind Pharm | pmid:21204738 |
| Stead SL et al. | Development and validation of a potentiometric biosensor assay for tylosin with demonstrated applicability for the detection of two other antimicrobial growth-promoter compounds in feedstuffs. | 2011 | Food Addit Contam Part A Chem Anal Control Expo Risk Assess | pmid:21574083 |
| Kucerova Z et al. | Antimicrobial susceptibility of Actinobacillus pleuropneumoniae isolates from clinical outbreaks of porcine respiratory diseases. | 2011 | Vet. Microbiol. | pmid:21316872 |
| Hidalgo à et al. | Trends towards lower antimicrobial susceptibility and characterization of acquired resistance among clinical isolates of Brachyspira hyodysenteriae in Spain. | 2011 | Antimicrob. Agents Chemother. | pmid:21555771 |
| Guan S et al. | Immunosuppressive activity of tilmicosin on the immune responses in mice. | 2011 | Immunopharmacol Immunotoxicol | pmid:20718577 |
| Lombardi KR et al. | Pharmacokinetics of tilmicosin in beef cattle following intravenous and subcutaneous administration. | 2011 | J. Vet. Pharmacol. Ther. | pmid:21323676 |
| Xie S et al. | Acute toxicity study of tilmicosin-loaded hydrogenated castor oil-solid lipid nanoparticles. | 2011 | Part Fibre Toxicol | pmid:22098626 |
| Danzeisen JL et al. | Modulations of the chicken cecal microbiome and metagenome in response to anticoccidial and growth promoter treatment. | 2011 | PLoS ONE | pmid:22114729 |
| Forrester CA et al. | Mycoplasma gallisepticum in pheasants and the efficacy of tylvalosin to treat the disease. | 2011 | Avian Pathol. | pmid:22107092 |
| Bohm DA et al. | Preparation and characterisation of in-house reference material of tylosin in honey and results of a proficiency test. | 2011 | Anal. Chim. Acta | pmid:21742117 |
| Dinh QT et al. | Measurement of trace levels of antibiotics in river water using on-line enrichment and triple-quadrupole LC-MS/MS. | 2011 | Talanta | pmid:21807177 |
| Gerchman I et al. | Characterization of in vivo-acquired resistance to macrolides of Mycoplasma gallisepticum strains isolated from poultry. | 2011 | Vet. Res. | pmid:21810258 |
| Ashenafi D et al. | An improved liquid chromatographic method for the analysis of tylosin and its impurities. | 2011 | J Sep Sci | pmid:21812113 |
| Chelliapan S et al. | Tolerance of the antibiotic tylosin on treatment performance of an up-flow anaerobic stage reactor (UASR). | 2011 | Water Sci. Technol. | pmid:21866757 |
| Stone JJ et al. | Land application of tylosin and chlortetracycline swine manure: Impacts to soil nutrients and soil microbial community structure. | 2011 | J Environ Sci Health B | pmid:21877979 |
| Han AR et al. | Biosynthesis of glycosylated derivatives of tylosin in Streptomyces venezuelae. | 2011 | J. Microbiol. Biotechnol. | pmid:21715968 |
| McClary DG et al. | Relationship of in vitro minimum inhibitory concentrations of tilmicosin against Mannheimia haemolytica and Pasteurella multocida and in vivo tilmicosin treatment outcome among calves with signs of bovine respiratory disease. | 2011 | J. Am. Vet. Med. Assoc. | pmid:21718206 |
| Lust EB et al. | Human health hazards of veterinary medications: information for emergency departments. | 2011 | J Emerg Med | pmid:20045604 |
| Poehlsgaard J et al. | Visualizing the 16-membered ring macrolides tildipirosin and tilmicosin bound to their ribosomal site. | 2012 | ACS Chem. Biol. | pmid:22563863 |
| Eguchi K et al. | Establishment of evaluation method to determine effects of veterinary medicinal products on manure fermentation using small-scale composting apparatus. | 2012 | J. Biosci. Bioeng. | pmid:22595343 |
| Pakpour S et al. | Frequency of antibiotic resistance in a swine facility 2.5 years after a ban on antibiotics. | 2012 | Microb. Ecol. | pmid:21997543 |
| Rérat M et al. | Bovine respiratory disease: efficacy of different prophylactic treatments in veal calves and antimicrobial resistance of isolated Pasteurellaceae. | 2012 | Prev. Vet. Med. | pmid:21945813 |
| Apley MD et al. | Use estimates of in-feed antimicrobials in swine production in the United States. | 2012 | Foodborne Pathog. Dis. | pmid:22324295 |
| Blondeau JM et al. | Comparative minimum inhibitory and mutant prevention drug concentrations of enrofloxacin, ceftiofur, florfenicol, tilmicosin and tulathromycin against bovine clinical isolates of Mannheimia haemolytica. | 2012 | Vet. Microbiol. | pmid:22677482 |
| Sakai A et al. | Production of a hybrid 16-membered macrolide antibiotic by genetic engineering of Micromonospora sp. TPMA0041. | 2012 | J. Ind. Microbiol. Biotechnol. | pmid:22842988 |
| Srinivasan P et al. | Development of an HPLC method to analyze four veterinary antibiotics in soils and aqueous media and validation through fate studies. | 2012 | J Environ Sci Health A Tox Hazard Subst Environ Eng | pmid:22871010 |
| Er A and Yazar E | Effects of tylosin, tilmicosin and tulathromycin on inflammatory mediators in bronchoalveolar lavage fluid of lipopolysaccharide-induced lung injury. | 2012 | Acta Vet. Hung. | pmid:23160029 |
| Westermarck E and Wiberg M | Exocrine pancreatic insufficiency in the dog: historical background, diagnosis, and treatment. | 2012 | Top Companion Anim Med | pmid:23148848 |