Tylosin

Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Tylosin?

Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.

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Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Tylosin

PubChem Associated disorders and diseases

What pathways are associated with Tylosin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Tylosin?

Related references are published most in these journals:

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What functions are associated with Tylosin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Tylosin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Tylosin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Tylosin?

Knock-out

Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Tylosin

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Authors Title Published Journal PubMed Link
Chuard C et al. In-vitro and in-vivo evaluation of the antistaphylococcal activity of S-5556, a new 16-membered macrolide. 1992 J. Antimicrob. Chemother. pmid:1452498
Kádár-Pauncz J et al. Isolation and structure elucidation of new antibiotics related to angolamycin. 1992 J. Antibiot. pmid:1399843
Kageyama S et al. Synthesis of 3,4'-dideoxymycaminosyl tylonolide, a novel type of macrolide derivative. 1992 J. Antibiot. pmid:1548187
Mathieson PW et al. Mercuric chloride-treated brown Norway rats develop widespread tissue injury including necrotizing vasculitis. 1992 Lab. Invest. pmid:1625442
Arzey GG and Arzey KE Successful treatment of mycoplasmosis in layer chickens with single dose therapy. 1992 Aust. Vet. J. pmid:1379426
Kempf I et al. Efficacy of danofloxacin in the therapy of experimental mycoplasmosis in chicks. 1992 Res. Vet. Sci. pmid:1332154
Malanicheva IA et al. [Protoplast fusion in Streptomyces fradiae strains producing neomycin and tylosin]. 1992 Antibiot. Khimioter. pmid:1296531
Baltz RH et al. Transposition of Tn5096 and related transposons in Streptomyces species. 1992 Gene pmid:1319378
Brahimi-Horn MC et al. Synthesis of hydrolytic enzymes during production of tylosin by Streptomyces fradiae. 1992 J. Ind. Microbiol. pmid:1381591
Gummow B et al. The diagnosis and treatment of bovine genital ureaplasmosis: a case study. 1992 J S Afr Vet Assoc pmid:1404223
Chin NX and Neu HC In vitro activity of MC-352, a new 16-membered macrolide. 1992 Antimicrob. Agents Chemother. pmid:1416853
Galyean ML et al. Performance of feedlot steers fed diets containing laidlomycin propionate or monensin plus tylosin, and effects of laidlomycin propionate concentration on intake patterns and ruminal fermentation in beef steers during adaptation to a high-concentrate diet. 1992 J. Anim. Sci. pmid:1429270
Fodor L et al. Treatment of calf pneumonia with tilmicosin. 1993 Acta Vet. Hung. pmid:8116500
Hartman EG and Geryl J Comparison between the minimal inhibitory concentration of tilmicosin and oxytetracycline for bovine pneumonic Pasteurella haemolytica isolates. 1993 Vet Q pmid:8122359
Takhirov MT et al. [Determination of tylosin in the water supply using a chromatographic method]. 1993 Gig Sanit pmid:8244081
Tanner AC et al. Adaptation of the Sensititre broth microdilution technique to antimicrobial susceptibility testing of Mycoplasma hyopneumoniae. 1993 Vet. Microbiol. pmid:8273275
Stephens CP et al. In-vitro antibacterial properties of tilmicosin against Australian isolates of Pasteurella multocida and Pasteurella haemolytica from cattle. 1993 Aust. Vet. J. pmid:8257321
Westermarck E et al. Effect of treatment on the jejunal and colonic bacterial flora of dogs with exocrine pancreatic insufficiency. 1993 Pancreas pmid:8302792
Cooper AC et al. In vitro activity of danofloxacin, tylosin and oxytetracycline against mycoplasmas of veterinary importance. 1993 Res. Vet. Sci. pmid:8393208
Huang SL et al. Purification and properties of NADPH-dependent tylosin reductase from Streptomyces fradiae. 1993 J. Biol. Chem. pmid:8360186
Binder S et al. [The effectiveness of tilmicosin in respiratory diseases of swine]. 1993 Berl. Munch. Tierarztl. Wochenschr. pmid:8431202
Cester CC et al. Effect of stage of oestrous cycle on tylosin disposition in genital tract secretions of cows. 1993 Res. Vet. Sci. pmid:8434145
Jordan FT et al. A comparison of the efficacy of danofloxacin and tylosin in the control of Mycoplasma gallisepticum infection in broiler chicks. 1993 J. Vet. Pharmacol. Ther. pmid:8386777
Meisel ML et al. Tylosin inhibits the steroidogenesis in mouse Leydig cells "in vitro". 1993 Life Sci. pmid:8390595
Kageyama S et al. Synthesis of 3-deoxy-3,4-didehydro derivatives of 5-O-mycaminosyltylonolide, 5-O-(4-deoxymycaminosyl) tylonolide, and desmycosin. 1993 J. Antibiot. pmid:8407589
Roets E et al. Quantitative analysis of tylosin by column liquid chromatography. 1993 J. Chromatogr. pmid:8445000
Danielson ND et al. Simple methods for the qualitative identification and quantitative determination of macrolide antibiotics. 1993 J Pharm Biomed Anal pmid:8504183
Lee SH and Lee KJ Aspartate aminotransferase and tylosin biosynthesis in Streptomyces fradiae. 1993 Appl. Environ. Microbiol. pmid:8481008
Morck DW et al. Prophylactic efficacy of tilmicosin for bovine respiratory tract disease. 1993 J. Am. Vet. Med. Assoc. pmid:8428833
Jordan WH et al. A review of the toxicology of the antibiotic MICOTIL 300. 1993 Vet Hum Toxicol pmid:8470360
Arisawa A et al. Cloning and nucleotide sequences of two genes involved in the 4''-O-acylation of macrolide antibiotics from Streptomyces thermotolerans. 1993 Biosci. Biotechnol. Biochem. pmid:7764361
Riddell KP et al. Antibiotic treatment of bovine embryos. 1993 J. Assist. Reprod. Genet. pmid:8069094
Clary EM et al. Supplemental fat and ionophores in finishing diets: feedlot performance and ruminal digesta kinetics in steers. 1993 J. Anim. Sci. pmid:8270535
Migaki TT et al. Efficacy of danofloxacin and tylosin in the control of mycoplasmosis in chicks infected with tylosin-susceptible or tylosin-resistant field isolates of Mycoplasma gallisepticum. 1993 Apr-Jun Avian Dis. pmid:8395803
Tanner AC et al. A comparison of danofloxacin and tylosin in the control of induced Mycoplasma gallisepticum infection in broiler chicks. 1993 Apr-Jun Avian Dis. pmid:8395804
Meisel ML et al. Effects of tylosin on the pituitary-gonadal axis in male rats. 1993 Apr-May Pharmacol. Toxicol. pmid:8372057
Coleman MR et al. The need for larger analytical samples with granulated feed additives. 1993 Sep-Oct J AOAC Int pmid:8241822
Ueda Y et al. Effect of terdecamycin on experimentally induced Mycoplasma hyopneumoniae-infection in pigs. 1994 Zentralblatt Veterinarmedizin Reihe B pmid:7839749
Parker RM and Patel RK Determination of tilmicosin in ovine milk using high-performance liquid chromatography. 1994 Analyst pmid:7879857
Delepine B et al. Identification of tylosin in bovine muscle at the maximum residue limit level by liquid chromatography-mass spectrometry, using a particle beam interface. 1994 Analyst pmid:7879883
Kirchgessner M et al. [The effect of avilamycin and tylosin on the apparent digestibility of iron, zinc, copper, manganese and selenium in the beginning and ending performance of swine]. 1994 Arch Tierernahr pmid:7778980
Scott DW et al. Efficacy of tylosin tablets for the treatment of pyoderma due to Staphylococcus intermedius infection in dogs. 1994 Can. Vet. J. pmid:7994702
Narandja A et al. Structure-activity relationship among polyhydro derivatives of tylosin. 1994 J. Antibiot. pmid:8040056
Scott PR Field study of undifferentiated respiratory disease in housed beef calves. 1994 Vet. Rec. pmid:8203107
Coronato S et al. A simple method to eliminate mycoplasma from cell cultures. 1994 J. Virol. Methods pmid:8175949
Kageyama S and Tsuchiya T Synthesis of 2-C-methyl derivatives of 3,4'-dideoxymycaminosyltylonolide, a novel type of 16-membered macrolide antibiotic. 1994 J. Antibiot. pmid:7928687
Trovatelli LD et al. The effect of some antibiotics on Enterococcus faecium SF 68 inoculated in germ-free mice. 1994 Microbiol. Res. pmid:7987613
Merson-Davies LA and Cundliffe E Analysis of five tylosin biosynthetic genes from the tyllBA region of the Streptomyces fradiae genome. 1994 Mol. Microbiol. pmid:7984112
Kelemen GH et al. Transcriptional attenuation control of the tylosin-resistance gene tlrA in Streptomyces fradiae. 1994 Mol. Microbiol. pmid:7534372
Tan ZL et al. Serum neutralizing antibodies against Fusobacterium necrophorum leukotoxin in cattle with experimentally induced or naturally developed hepatic abscesses. 1994 J. Anim. Sci. pmid:8157537