Tylosin

Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Tylosin?

Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Tylosin

PubChem Associated disorders and diseases

What pathways are associated with Tylosin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Tylosin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Tylosin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Tylosin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Tylosin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Tylosin?

Knock-out

Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Tylosin

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Authors Title Published Journal PubMed Link
Omura S et al. Chimeramycins: new macrolide antibiotics produced by hybrid biosynthesis. 1983 J. Antibiot. pmid:6860432
Kreisner M and Kietzmann M [Pharmacokinetics of chloramphenicol, tylosin and prednisolone in combined preparations. 1. Thin-layer chromatographic determination of chloramphenicol, tylosin and prednisolone in serum]. 1983 Zentralbl Veterinarmed A pmid:6407241
Omura S et al. Ribosome-binding activities and antimicrobial activities of tylosin and its related compounds. 1983 J. Antibiot. pmid:6662812
Matsubara H et al. Chemical modification of tylosin: synthesis of amino derivatives at C-20 position of tylosin and demycarosyltylosin. 1983 J. Antibiot. pmid:6662813
Omura S et al. Ammonium ion suppresses the biosynthesis of tylosin aglycone by interference with valine catabolism in Streptomyces fradiae. 1983 J. Antibiot. pmid:6662823
Wayner EA and Brooks CG Induction of NKCF-like activity in mixed lymphocyte-tumor cell culture: direct involvement of mycoplasma infection of tumor cells. 1984 J. Immunol. pmid:6230401
Truscott RB and Ruhnke HL The effect of antibiotics against bovine mycoplasmas and ureaplasmas. 1984 Can. J. Comp. Med. pmid:6232992
Omura S et al. Ammonium ions suppress the amino acid metabolism involved in the biosynthesis of protylonolide in a mutant of Streptomyces fradiae. 1984 J. Antibiot. pmid:6511663
Dafwang II et al. Broiler chick growth response to antibiotics, 1981-1982. 1984 Poult. Sci. pmid:6610176
Omura S et al. Effect of ammonium ion, inorganic phosphate and amino acids on the biosynthesis of protylonolide, a precursor of tylosin aglycone. 1984 J. Antibiot. pmid:6735923