Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.
To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Tylosin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Guo X et al. | Maize straw decorated with sulfide for tylosin removal from the water. | 2018 | Ecotoxicol. Environ. Saf. | pmid:29355772 |
Patyra E et al. | Development and validation of an LC-MS/MS method for the quantification of tiamulin, trimethoprim, tylosin, sulfadiazine and sulfamethazine in medicated feed. | 2018 | Food Addit Contam Part A Chem Anal Control Expo Risk Assess | pmid:29324179 |
Chen C et al. | Effect of composting and soil type on dissipation of veterinary antibiotics in land-applied manures. | 2018 | Chemosphere | pmid:29306199 |
Zhang B et al. | The effects of bio-available copper on macrolide antibiotic resistance genes and mobile elements during tylosin fermentation dregs co-composting. | 2018 | Bioresour. Technol. | pmid:29278844 |
Zheng W et al. | Development and validation of a simple solid-phase extraction method coupled with liquid chromatography-triple quadrupole tandem mass spectrometry for simultaneous determination of lincomycin, tylosin A and tylosin B in royal jelly. | 2018 | Biomed. Chromatogr. | pmid:29164636 |
Cornejo J et al. | Depletion of tylosin residues in feathers, muscle and liver from broiler chickens after completion of antimicrobial therapy. | 2018 | Food Addit Contam Part A Chem Anal Control Expo Risk Assess | pmid:29111882 |
Bhalsod GD et al. | Uptake and Accumulation of Pharmaceuticals in Overhead- and Surface-Irrigated Greenhouse Lettuce. | 2018 | J. Agric. Food Chem. | pmid:29293328 |
Huang L et al. | Pharmacokinetic-pharmacodynamic modeling of tylosin against Streptococcus suis in pigs. | 2018 | BMC Vet. Res. | pmid:30355326 |
Zhu L et al. | Evaluation of the antibacterial activity of tilmicosin-SLN against : in vitro and in vivo studies. | 2018 | Int J Nanomedicine | pmid:30147316 |
Lemli B et al. | Noncovalent Interaction of Tilmicosin with Bovine Serum Albumin. | 2018 | Molecules | pmid:30065238 |
De Baere S et al. | In vitro model to assess the adsorption of oral veterinary drugs to mycotoxin binders in a feed- and aflatoxin B1-containing buffered matrix. | 2018 | Food Addit Contam Part A Chem Anal Control Expo Risk Assess | pmid:30016205 |
Woolums AR et al. | Multidrug resistant Mannheimia haemolytica isolated from high-risk beef stocker cattle after antimicrobial metaphylaxis and treatment for bovine respiratory disease. | 2018 | Vet. Microbiol. | pmid:29981701 |
Guo X et al. | Sorption properties of tylosin on four different microplastics. | 2018 | Chemosphere | pmid:29933160 |
Stromer BS et al. | Tylosin sorption to diatomaceous earth described by Langmuir isotherm and Freundlich isotherm models. | 2018 | Chemosphere | pmid:29874766 |
Müller HC et al. | Effects of intermittent feeding of tylosin phosphate during the finishing period on feedlot performance, carcass characteristics, antimicrobial resistance, and incidence and severity of liver abscesses in steers. | 2018 | J. Anim. Sci. | pmid:29718254 |
Yin Y et al. | Iron and manganese oxides modified maize straw to remove tylosin from aqueous solutions. | 2018 | Chemosphere | pmid:29689529 |
Ishikawa NK et al. | Determination of tylosin excretion from sheep to assess tylosin spread to agricultural fields by manure application. | 2018 | Sci. Total Environ. | pmid:29579651 |
Canning P et al. | Variation in water disappearance, daily dose, and synovial fluid concentrations of tylvalosin and 3-O-acetyltylosin in commerical pigs during five day water medication with tylvalosin under field conditions. | 2018 | J. Vet. Pharmacol. Ther. | pmid:29572923 |
Dong H et al. | Synthesis and characterization of Ag/BiWO/GO composite for the fast degradation of tylosin under visible light. | 2018 | Environ Sci Pollut Res Int | pmid:29442310 |
Qiu G et al. | Macrolide-Resistance Selection in Tibetan Pigs with a High Load of Mycoplasma hyopneumoniae. | 2018 | Microb. Drug Resist. | pmid:29271698 |
Ling Z et al. | Tilmicosin- and florfenicol-loaded hydrogenated castor oil-solid lipid nanoparticles to pigs: Combined antibacterial activities and pharmacokinetics. | 2018 | J. Vet. Pharmacol. Ther. | pmid:29139136 |
Lowell JE et al. | Growth performance, carcass quality, fresh belly characteristics, and commercial bacon slicing yields of growing-finishing pigs fed a subtherapeutic dose of an antibiotic, a natural antimicrobial, or not fed an antibiotic or antimicrobial. | 2018 | Meat Sci. | pmid:29107868 |
Wang J et al. | Pharmacokinetics of tildipirosin in beagle dogs. | 2018 | J. Vet. Pharmacol. Ther. | pmid:28892155 |
Washington MT et al. | Monitoring tylosin and sulfamethazine in a tile-drained agricultural watershed using polar organic chemical integrative sampler (POCIS). | 2018 | Sci. Total Environ. | pmid:28854391 |
Mohammadsadegh M | Impact of intramammary tilmicosin infusion as a dry cow therapy. | 2018 | J. Vet. Pharmacol. Ther. | pmid:28600854 |
Makarov GI et al. | Structural Insight into Interaction between C20 Phenylalanyl Derivative of Tylosin and Ribosomal Tunnel. | 2017 | Biochemistry Mosc. | pmid:28941460 |
Berman J et al. | A randomised clinical trial of a metaphylactic treatment with tildipirosin for bovine respiratory disease in veal calves. | 2017 | BMC Vet. Res. | pmid:28615070 |
Li B et al. | EFFICACY AND SAFETY OF BAN HUANG ORAL LIQUID FOR TREATING BOVINE RESPIRATORY DISEASES. | 2017 | Afr J Tradit Complement Altern Med | pmid:28573221 |
Krongdang S et al. | Multilocus sequence typing, biochemical and antibiotic resistance characterizations reveal diversity of North American strains of the honey bee pathogen Paenibacillus larvae. | 2017 | PLoS ONE | pmid:28467471 |
Kreizinger Z et al. | Antibiotic susceptibility profiles of Mycoplasma synoviae strains originating from Central and Eastern Europe. | 2017 | BMC Vet. Res. | pmid:29149886 |
Qekwana DN et al. | Patterns and predictors of antimicrobial resistance among Staphylococcus spp. from canine clinical cases presented at a veterinary academic hospital in South Africa. | 2017 | BMC Vet. Res. | pmid:28454567 |
Weber NR et al. | Batch medication of intestinal infections in nursery pigs-A randomised clinical trial on the efficacy of treatment strategy, type of antibiotic and bacterial load on average daily weight gain. | 2017 | Prev. Vet. Med. | pmid:28107883 |
Zhang N et al. | Determination of the Mutant Selection Window and Evaluation of the Killing of Mycoplasma gallisepticum by Danofloxacin, Doxycycline, Tilmicosin, Tylvalosin and Valnemulin. | 2017 | PLoS ONE | pmid:28052123 |
Timsit E et al. | Effects of nasal instillation of a nitric oxide-releasing solution or parenteral administration of tilmicosin on the nasopharyngeal microbiota of beef feedlot cattle at high-risk of developing respiratory tract disease. | 2017 | Res. Vet. Sci. | pmid:28231472 |
De Mil T et al. | Influence of mycotoxin binders on the oral bioavailability of tylosin, doxycycline, diclazuril, and salinomycin in fed broiler chickens. | 2017 | Poult. Sci. | pmid:28160001 |
Sato T et al. | Mycoplasma bovis isolates from dairy calves in Japan have less susceptibility than a reference strain to all approved macrolides associated with a point mutation (G748A) combined with multiple species-specific nucleotide alterations in 23S rRNA. | 2017 | Microbiol. Immunol. | pmid:28504455 |
Weinroth MD et al. | Rapid Communication: 16S ribosomal ribonucleic acid characterization of liver abscesses in feedlot cattle from three states in the United States. | 2017 | J. Anim. Sci. | pmid:29108068 |
Zhang YJ et al. | Temporal succession of soil antibiotic resistance genes following application of swine, cattle and poultry manures spiked with or without antibiotics. | 2017 | Environ. Pollut. | pmid:28964602 |
Ruiz VE et al. | A single early-in-life macrolide course has lasting effects on murine microbial network topology and immunity. | 2017 | Nat Commun | pmid:28894149 |
Hossain A et al. | Occurrence, distribution, ecological and resistance risks of antibiotics in surface water of finfish and shellfish aquaculture in Bangladesh. | 2017 | Chemosphere | pmid:28888121 |
Amachawadi RG et al. | Bacterial flora of liver abscesses in crossbred beef cattle and Holstein steers fed finishing diets with or without tylosin. | 2017 | J. Anim. Sci. | pmid:28805921 |
Sugawara A et al. | 5-O-Mycaminosyltylonolide antibacterial derivatives: design, synthesis and bioactivity. | 2017 | J. Antibiot. | pmid:28559578 |
Teixeira AGV et al. | Efficacy of tildipirosin metaphylaxis for the prevention of respiratory disease, otitis and mortality in pre-weaned Holstein calves. | 2017 | Vet. J. | pmid:28093111 |
Cheng J et al. | Microstructure and antioxidative capacity of the microalgae mutant Chlorella PY-ZU1 during tilmicosin removal from wastewater under 15% CO. | 2017 | J. Hazard. Mater. | pmid:27829514 |
Ling Z et al. | Preparation, characterization, and pharmacokinetics of tilmicosin- and florfenicol-loaded hydrogenated castor oil-solid lipid nanoparticles. | 2017 | J. Vet. Pharmacol. Ther. | pmid:27687707 |
Li B et al. | Determination of antibacterial agent tilmicosin in pig plasma by LC/MS/MS and its application to pharmacokinetics. | 2017 | Biomed. Chromatogr. | pmid:27564248 |
Prats-van der Ham M et al. | Molecular resistance mechanisms of Mycoplasma agalactiae to macrolides and lincomycin. | 2017 | Vet. Microbiol. | pmid:29102109 |
Ray P et al. | Fate and Effect of Antibiotics in Beef and Dairy Manure during Static and Turned Composting. | 2017 | J. Environ. Qual. | pmid:28177414 |
Foster DM et al. | Comparison of direct sampling and brochoalveolar lavage for determining active drug concentrations in the pulmonary epithelial lining fluid of calves injected with enrofloxacin or tilmicosin. | 2017 | J. Vet. Pharmacol. Ther. | pmid:28457009 |
Zhang L et al. | Pharmacokinetics of tilmicosin in healthy pigs and in pigs experimentally infected with . | 2017 | J. Vet. Sci. | pmid:28385011 |