Tylosin
Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Tylosin?
Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (6)
- Proc. Natl. Acad. Sci. U.S.A. (2)
- Appl. Environ. Microbiol. (2)
- Others (6)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Tylosin
PubChem Associated disorders and diseases
What pathways are associated with Tylosin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Tylosin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Tylosin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Tylosin?
There are no associated biomedical information in the current reference collection.
What genes are associated with Tylosin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (9)
- Microbiology (Reading, Engl.) (3)
- FEMS Microbiol. Lett. (2)
- Others (13)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Tylosin?
Knock-out
Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with Tylosin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Skogerboe TL et al. | Comparative efficacy of tulathromycin versus florfenicol and tilmicosin against undifferentiated bovine respiratory disease in feedlot cattle. | 2005 | Vet. Ther. | pmid:16094565 |
| Caldow M et al. | Development and validation of an optical SPR biosensor assay for tylosin residues in honey. | 2005 | J. Agric. Food Chem. | pmid:16159159 |
| Chun S et al. | Effect of agricultural antibiotics on the persistence and transformation of 17beta-estradiol in a Sequatchie loam. | 2005 | J Environ Sci Health B | pmid:16190018 |
| Clay SA et al. | Tylosin sorption to silty clay loam soils, swine manure, and sand. | 2005 | J Environ Sci Health B | pmid:16194921 |
| Brumbaugh GW et al. | Effect of tilmicosin on chemotactic, phagocytic, and bactericidal activities of bovine and porcine alveolar macrophages. | 2002 | Am. J. Vet. Res. | pmid:16206777 |
| Chander Y et al. | Antibacterial activity of soil-bound antibiotics. | 2005 Nov-Dec | J. Environ. Qual. | pmid:16221813 |
| Kumar K et al. | Antibiotic uptake by plants from soil fertilized with animal manure. | 2005 Nov-Dec | J. Environ. Qual. | pmid:16221828 |
| Rozeboom DW et al. | Effects of mannan oligosaccharide and an antimicrobial product in nursery diets on performance of pigs reared on three different farms. | 2005 | J. Anim. Sci. | pmid:16230663 |
| Pringle M et al. | Tiamulin resistance in porcine Brachyspira pilosicoli isolates. | 2006 | Res. Vet. Sci. | pmid:16253666 |
| Mathieson PW et al. | Mercuric chloride-treated brown Norway rats develop widespread tissue injury including necrotizing vasculitis. | 1992 | Lab. Invest. | pmid:1625442 |
| Jensen LB and Aarestrup FM | Regulation of the erm(C) gene in Staphylococci from reservoir with different usage of macrolides. | 2005 | Acta Vet. Scand. | pmid:16261929 |
| Ayling RD et al. | Assessing the in vitro effectiveness of antimicrobials against Mycoplasma mycoides subsp. mycoides small-colony type to reduce contagious bovine pleuropneumonia infection. | 2005 | Antimicrob. Agents Chemother. | pmid:16304194 |
| Beier RC et al. | Production and characterization of monoclonal antibodies against the antibiotic tilmicosin. | 2005 | J. Agric. Food Chem. | pmid:16332115 |
| Fu H et al. | Synthesis and in vitro antibiotic activity of 16-membered 9-O-arylalkyloxime macrolides. | 2006 | Bioorg. Med. Chem. Lett. | pmid:16343900 |
| Westermarck E et al. | Effect of diet and tylosin on chronic diarrhea in beagles. | 2005 Nov-Dec | J. Vet. Intern. Med. | pmid:16355675 |
| Chelliapan S et al. | Performance of an up-flow anaerobic stage reactor (UASR) in the treatment of pharmaceutical wastewater containing macrolide antibiotics. | 2006 | Water Res. | pmid:16387347 |
| Jacobsen AM and Halling-Sørensen B | Multi-component analysis of tetracyclines, sulfonamides and tylosin in swine manure by liquid chromatography-tandem mass spectrometry. | 2006 | Anal Bioanal Chem | pmid:16485090 |
| Jung WS et al. | Heterologous expression of tylosin polyketide synthase and production of a hybrid bioactive macrolide in Streptomyces venezuelae. | 2006 | Appl. Microbiol. Biotechnol. | pmid:16493552 |
| Carlson JC and Mabury SA | Dissipation kinetics and mobility of chlortetracycline, tylosin, and monensin in an agricultural soil in Northumberland County, Ontario, Canada. | 2006 | Environ. Toxicol. Chem. | pmid:16494218 |
| Nozal Nalda MJ et al. | Trace analysis of antibacterial tylosin A, B, C and D in honey by liquid chromatography-electrospray ionization-mass spectrometry. | 2006 | J Sep Sci | pmid:16544883 |