Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.
To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Tylosin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Smith GW et al. | Elimination kinetics of tilmicosin following intramammary administration in lactating dairy cattle. | 2009 | J. Am. Vet. Med. Assoc. | pmid:19210246 |
Kouvela EC et al. | Distinct mode of interaction of a novel ketolide antibiotic that displays enhanced antimicrobial activity. | 2009 | Antimicrob. Agents Chemother. | pmid:19164155 |
Meyer NF et al. | Effect of essential oils, tylosin, and monensin on finishing steer performance, carcass characteristics, liver abscesses, ruminal fermentation, and digestibility. | 2009 | J. Anim. Sci. | pmid:19359504 |
Christodoulopoulos G | Adverse outcome of using tilmicosin in a lamb with multiple ventricular septal defects. | 2009 | Can. Vet. J. | pmid:19337615 |
Khaliq S et al. | Production of tylosin in solid-state fermentation by Streptomyces fradiae NRRL-2702 and its gamma-irradiated mutant (gamma-1). | 2009 | Lett. Appl. Microbiol. | pmid:19780953 |
Hu D and Coats JR | Laboratory evaluation of mobility and sorption for the veterinary antibiotic, tylosin, in agricultural soils. | 2009 | J Environ Monit | pmid:19724833 |
Khalifeh MS et al. | Assessment of humoral and cellular-mediated immune response in chickens treated with tilmicosin, florfenicol, or enrofloxacin at the time of Newcastle disease vaccination. | 2009 | Poult. Sci. | pmid:19762865 |
Guedes RM et al. | Use of tylvalosin-medicated feed to control porcine proliferative enteropathy. | 2009 | Vet. Rec. | pmid:19767637 |
Fitzgerald J | Administration of micotil. | 2009 | Vet. Rec. | pmid:19767643 |
Stone JJ et al. | Effect of antimicrobial compounds tylosin and chlortetracycline during batch anaerobic swine manure digestion. | 2009 | Water Res. | pmid:19695662 |
Atef M et al. | Effect of albendazole administration on pharmacokinetic aspects of tylosin in lactating goats. | 2009 | Drug Metab Lett | pmid:19702546 |
Hilton GG et al. | Effects of feeding zilpaterol hydrochloride with and without monensin and tylosin on carcass cutability and meat palatability of beef steers. | 2009 | J. Anim. Sci. | pmid:19028853 |
Byrne-Bailey KG et al. | Prevalence of sulfonamide resistance genes in bacterial isolates from manured agricultural soils and pig slurry in the United Kingdom. | 2009 | Antimicrob. Agents Chemother. | pmid:19064898 |
Petropoulos AD et al. | Time-resolved binding of azithromycin to Escherichia coli ribosomes. | 2009 | J. Mol. Biol. | pmid:19071138 |
Blackwell PA et al. | Effects of agricultural conditions on the leaching behaviour of veterinary antibiotics in soils. | 2009 | Chemosphere | pmid:19128817 |
Chénier MR and Juteau P | Fate of chlortetracycline- and tylosin-resistant bacteria in an aerobic thermophilic sequencing batch reactor treating swine waste. | 2009 | Microb. Ecol. | pmid:19125305 |
Suchodolski JS et al. | The effect of the macrolide antibiotic tylosin on microbial diversity in the canine small intestine as demonstrated by massive parallel 16S rRNA gene sequencing. | 2009 | BMC Microbiol. | pmid:19799792 |
Warner K et al. | Control of Ornithobacterium rhinotracheale in poultry. | 2009 | Vet. Rec. | pmid:19946131 |
Hao H et al. | 23S rRNA mutation A2074C conferring high-level macrolide resistance and fitness cost in Campylobacter jejuni. | 2009 | Microb. Drug Resist. | pmid:19857128 |
Khaliq S et al. | Change in colony morphology and kinetics of tylosin production after UV and gamma irradiation mutagenesis of Streptomyces fradiae NRRL-2702. | 2009 | Microbiol. Res. | pmid:17475458 |