Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.
To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Tylosin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Mitchell SM et al. | Hydrolysis of amphenicol and macrolide antibiotics: Chloramphenicol, florfenicol, spiramycin, and tylosin. | 2015 | Chemosphere | pmid:25618189 |
Li Y et al. | Effects of Cu exposure on enzyme activities and selection for microbial tolerances during swine-manure composting. | 2015 | J. Hazard. Mater. | pmid:25464290 |
Abdel-Daim MM et al. | Synergistic protective role of mirazid (Commiphora molmol) and ascorbic acid against tilmicosin-induced cardiotoxicity in mice. | 2015 | Can. J. Physiol. Pharmacol. | pmid:25429612 |
Matsushima P et al. | Transduction and transformation of plasmid DNA in Streptomyces fradiae strains that express different levels of restriction. | 1989 | J. Bacteriol. | pmid:2542216 |
Dieste-Pérez L et al. | Studies on a suitable antibiotic therapy for treating swine brucellosis. | 2015 | J. Vet. Pharmacol. Ther. | pmid:25413993 |
Zhu H et al. | Immobilization of Streptomyces thermotolerans 11432 on polyurethane foam to improve production of acetylisovaleryltylosin. | 2015 | J. Ind. Microbiol. Biotechnol. | pmid:25413211 |
Maxwell CL et al. | Effects of beef production system on animal performance and carcass characteristics. | 2014 | J. Anim. Sci. | pmid:25403195 |
VoeÄkova TA et al. | [Bion-M1. Biological activities of microorganisms under the conditions of a 30-day space flight]. | 2014 | Aviakosm Ekolog Med | pmid:25365877 |
Tennant TC et al. | Comparison of tulathromycin and tilmicosin on the prevalence and severity of bovine respiratory disease in feedlot cattle in association with feedlot performance, carcass characteristics, and economic factors. | 2014 | J. Anim. Sci. | pmid:25349362 |
Holman DB and Chénier MR | Temporal changes and the effect of subtherapeutic concentrations of antibiotics in the gut microbiota of swine. | 2014 | FEMS Microbiol. Ecol. | pmid:25187398 |
TavÃo MM et al. | In vitro activity of tylvalosin against Spanish field strains of Mycoplasma hyopneumoniae. | 2014 | Vet. Rec. | pmid:25185108 |
Avci T and Elmas M | Milk and blood pharmacokinetics of tylosin and tilmicosin following parenteral administrations to cows. | 2014 | ScientificWorldJournal | pmid:25177733 |
Usui M et al. | Selection of macrolide-resistant Campylobacter in pigs treated with macrolides. | 2014 | Vet. Rec. | pmid:25163817 |
Kilpinen S et al. | Efficacy of two low-dose oral tylosin regimens in controlling the relapse of diarrhea in dogs with tylosin-responsive diarrhea: a prospective, single-blinded, two-arm parallel, clinical field trial. | 2014 | Acta Vet. Scand. | pmid:25096196 |
Solliec M et al. | Analysis of trimethoprim, lincomycin, sulfadoxin and tylosin in swine manure using laser diode thermal desorption-atmospheric pressure chemical ionization-tandem mass spectrometry. | 2014 | Talanta | pmid:25059125 |
Fujiwara T et al. | 19-Deformyl-4'-deoxydesmycosin (TMC-016): synthesis and biological properties of a unique 16-membered macrolide antibiotic. | 1989 | J. Antibiot. | pmid:2500413 |
Chen X et al. | Preparation and evaluation of tilmicosin-loaded hydrogenated castor oil nanoparticle suspensions of different particle sizes. | 2014 | Int J Nanomedicine | pmid:24920902 |
Sehati N et al. | Extraction and preconcentration of tylosin from milk samples through functionalized TiOâ‚‚ nanoparticles reinforced with a hollow fiber membrane as a novel solid/liquid-phase microextraction technique. | 2014 | J Sep Sci | pmid:24890459 |
Muñoz R et al. | Withdrawal times of oxytetracycline and tylosin in eggs of laying hens after oral administration. | 2014 | J. Food Prot. | pmid:24853528 |
Zhao Z et al. | Tylvalosin exhibits anti-inflammatory property and attenuates acute lung injury in different models possibly through suppression of NF-κB activation. | 2014 | Biochem. Pharmacol. | pmid:24792436 |