Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.
To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Tylosin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Mercadante VR et al. | Effects of anti-phospholipase A(2) antibody supplementation on dry matter intake feed efficiency, acute phase response, and blood differentials of steers fed forage- and grain-based diets. | 2015 | J. Anim. Sci. | pmid:26020758 |
Lysnyansky I et al. | Decreased Susceptibility to Macrolide-Lincosamide in Mycoplasma synoviae Is Associated with Mutations in 23S Ribosomal RNA. | 2015 | Microb. Drug Resist. | pmid:25734368 |
Luo H et al. | Identification of ribosomal RNA methyltransferase gene ermF in Riemerella anatipestifer. | 2015 | Avian Pathol. | pmid:25690020 |
Dieste-Pérez L et al. | Studies on a suitable antibiotic therapy for treating swine brucellosis. | 2015 | J. Vet. Pharmacol. Ther. | pmid:25413993 |
Amachawadi RG et al. | Effects of in-feed copper and tylosin supplementations on copper and antimicrobial resistance in faecal enterococci of feedlot cattle. | 2015 | J. Appl. Microbiol. | pmid:25739516 |
Mitchell SM et al. | Hydrolysis of amphenicol and macrolide antibiotics: Chloramphenicol, florfenicol, spiramycin, and tylosin. | 2015 | Chemosphere | pmid:25618189 |
Li Y et al. | Effects of Cu exposure on enzyme activities and selection for microbial tolerances during swine-manure composting. | 2015 | J. Hazard. Mater. | pmid:25464290 |
Abdel-Daim MM et al. | Synergistic protective role of mirazid (Commiphora molmol) and ascorbic acid against tilmicosin-induced cardiotoxicity in mice. | 2015 | Can. J. Physiol. Pharmacol. | pmid:25429612 |
Zhu H et al. | Immobilization of Streptomyces thermotolerans 11432 on polyurethane foam to improve production of acetylisovaleryltylosin. | 2015 | J. Ind. Microbiol. Biotechnol. | pmid:25413211 |
Maxwell CL et al. | Effects of beef production system on animal performance and carcass characteristics. | 2014 | J. Anim. Sci. | pmid:25403195 |
Tennant TC et al. | Comparison of tulathromycin and tilmicosin on the prevalence and severity of bovine respiratory disease in feedlot cattle in association with feedlot performance, carcass characteristics, and economic factors. | 2014 | J. Anim. Sci. | pmid:25349362 |
Holman DB and Chénier MR | Temporal changes and the effect of subtherapeutic concentrations of antibiotics in the gut microbiota of swine. | 2014 | FEMS Microbiol. Ecol. | pmid:25187398 |
Avci T and Elmas M | Milk and blood pharmacokinetics of tylosin and tilmicosin following parenteral administrations to cows. | 2014 | ScientificWorldJournal | pmid:25177733 |
Kilpinen S et al. | Efficacy of two low-dose oral tylosin regimens in controlling the relapse of diarrhea in dogs with tylosin-responsive diarrhea: a prospective, single-blinded, two-arm parallel, clinical field trial. | 2014 | Acta Vet. Scand. | pmid:25096196 |
Chen X et al. | Preparation and evaluation of tilmicosin-loaded hydrogenated castor oil nanoparticle suspensions of different particle sizes. | 2014 | Int J Nanomedicine | pmid:24920902 |
Beck P et al. | Additive effects of growth promoting technologies on performance of grazing steers and economics of the wheat pasture enterprise. | 2014 | J. Anim. Sci. | pmid:24492552 |
Kawai K et al. | Antimicrobial susceptibilities of Mycoplasma isolated from bovine mastitis in Japan. | 2014 | Anim. Sci. J. | pmid:24261609 |
Marosevic D et al. | In vivo spread of macrolide-lincosamide-streptogramin B (MLSB) resistance--a model study in chickens. | 2014 | Vet. Microbiol. | pmid:24467930 |
Usui M et al. | Selection of macrolide-resistant Campylobacter in pigs treated with macrolides. | 2014 | Vet. Rec. | pmid:25163817 |
TavÃo MM et al. | In vitro activity of tylvalosin against Spanish field strains of Mycoplasma hyopneumoniae. | 2014 | Vet. Rec. | pmid:25185108 |
Solliec M et al. | Analysis of trimethoprim, lincomycin, sulfadoxin and tylosin in swine manure using laser diode thermal desorption-atmospheric pressure chemical ionization-tandem mass spectrometry. | 2014 | Talanta | pmid:25059125 |
Sehati N et al. | Extraction and preconcentration of tylosin from milk samples through functionalized TiOâ‚‚ nanoparticles reinforced with a hollow fiber membrane as a novel solid/liquid-phase microextraction technique. | 2014 | J Sep Sci | pmid:24890459 |
Ferrag-Siagh F et al. | Electro-Fenton pretreatment for the improvement of tylosin biodegradability. | 2014 | Environ Sci Pollut Res Int | pmid:24705893 |
Entorf M et al. | Tylosin susceptibility of Staphylococci from bovine mastitis. | 2014 | Vet. Microbiol. | pmid:24461550 |
Ji LW et al. | Comparative pharmacokinetics and bioavailability of tylosin tartrate and tylosin phosphate after a single oral and i.v. administration in chickens. | 2014 | J. Vet. Pharmacol. Ther. | pmid:24325541 |
Buß M et al. | Quality control ranges for tylosin 30 μg and 15 μg discs applicable to Staphylococcus aureus ATCC(R) 25923. | 2014 | J. Antimicrob. Chemother. | pmid:23928021 |
Guo X et al. | The influences of pH and ionic strength on the sorption of tylosin on goethite. | 2014 | Environ Sci Pollut Res Int | pmid:24197966 |
Pei Z et al. | Effects of copper and aluminum on the adsorption of sulfathiazole and tylosin on peat and soil. | 2014 | Environ. Pollut. | pmid:24201036 |
Khaliq S et al. | Characterization of mutations in regulatory genes of Tyl cluster leading to overexpression of tylosin in mutant γ-1 of Streptomyces fradiae NRRL-2702. | 2014 | Appl. Microbiol. Biotechnol. | pmid:24270892 |
Kolanović BS et al. | Tylosin content in meat and honey samples over a two-year period in Croatia. | 2014 | J Immunoassay Immunochem | pmid:24063615 |
Zhao Z et al. | Tylvalosin exhibits anti-inflammatory property and attenuates acute lung injury in different models possibly through suppression of NF-κB activation. | 2014 | Biochem. Pharmacol. | pmid:24792436 |
VoeÄkova TA et al. | [Bion-M1. Biological activities of microorganisms under the conditions of a 30-day space flight]. | 2014 | Aviakosm Ekolog Med | pmid:25365877 |
Kim HB et al. | Effects of tylosin administration on C-reactive protein concentration and carriage of Salmonella enterica in pigs. | 2014 | Am. J. Vet. Res. | pmid:24762018 |
Lerner U et al. | Acquired resistance to the 16-membered macrolides tylosin and tilmicosin by Mycoplasma bovis. | 2014 | Vet. Microbiol. | pmid:24393633 |
Amrine DE et al. | Pulmonary lesions and clinical disease response to Mannheimia haemolytica challenge 10 days following administration of tildipirosin or tulathromycin. | 2014 | J. Anim. Sci. | pmid:24243906 |
Srinivasan P et al. | Sorption of selected veterinary antibiotics onto dairy farming soils of contrasting nature. | 2014 | Sci. Total Environ. | pmid:24326064 |
Muñoz R et al. | Withdrawal times of oxytetracycline and tylosin in eggs of laying hens after oral administration. | 2014 | J. Food Prot. | pmid:24853528 |
Meyer NF et al. | Effects of monensin and tylosin in finishing diets containing corn wet distillers grains with solubles with differing corn processing methods. | 2013 | J. Anim. Sci. | pmid:23422007 |
Garcés-Narro C et al. | Efficacy of low-dose tylvalosin for the control of clostridiosis in broilers and its effect on productive parameters. | 2013 | Poult. Sci. | pmid:23472021 |
Mitchell JD et al. | In vitro pharmacodynamics of gamithromycin against Mycoplasma mycoides subspecies mycoides Small Colony. | 2013 | Vet. J. | pmid:23810743 |
Chopra S et al. | Characterization of impurities in tylosin using dual liquid chromatography combined with ion trap mass spectrometry. | 2013 | Talanta | pmid:23598092 |
Amachawadi RG et al. | Occurrence of the transferable copper resistance gene tcrB among fecal enterococci of U.S. feedlot cattle fed copper-supplemented diets. | 2013 | Appl. Environ. Microbiol. | pmid:23666328 |
Whitehead TR and Cotta MA | Stored swine manure and swine faeces as reservoirs of antibiotic resistance genes. | 2013 | Lett. Appl. Microbiol. | pmid:23297734 |
Hao H et al. | Mutational and transcriptomic changes involved in the development of macrolide resistance in Campylobacter jejuni. | 2013 | Antimicrob. Agents Chemother. | pmid:23274667 |
Tsutsui A et al. | Antimalarial C-9 oxime derivatives from desmycosin, produced by click chemistry. | 2013 | J. Antibiot. | pmid:23232930 |
Mitchell SM et al. | The effects of the antibiotics ampicillin, florfenicol, sulfamethazine, and tylosin on biogas production and their degradation efficiency during anaerobic digestion. | 2013 | Bioresour. Technol. | pmid:24113548 |
Lin J et al. | Response of intestinal microbiota to antibiotic growth promoters in chickens. | 2013 | Foodborne Pathog. Dis. | pmid:23461609 |
Shishkina A et al. | Conjugates of amino acids and peptides with 5-o-mycaminosyltylonolide and their interaction with the ribosomal exit tunnel. | 2013 | Bioconjug. Chem. | pmid:24090034 |
Pinckney JL et al. | Sublethal effects of the antibiotic tylosin on estuarine benthic microalgal communities. | 2013 | Mar. Pollut. Bull. | pmid:23398744 |
Pilcher CM et al. | Impact of tylosin phosphate and distillers dried grains with solubles on energy and nutrient digestibility and flow through the gastrointestinal tract in growing pigs. | 2013 | J. Anim. Sci. | pmid:24126274 |