Tylosin

Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Tylosin?

Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Tylosin

MeSH term MeSH ID Detail
Enterotoxemia D004767 1 associated lipids
Bacillaceae Infections D016863 1 associated lipids
Erysipelothrix Infections D004889 1 associated lipids
Conjunctivitis, Viral D003236 1 associated lipids
Bovine Respiratory Disease Complex D048090 2 associated lipids
Primate Diseases D018419 2 associated lipids
Pneumonia of Calves, Enzootic D048089 2 associated lipids
Keratoconjunctivitis, Infectious D007639 2 associated lipids
Pneumonia of Swine, Mycoplasmal D045729 2 associated lipids
Pasteurellosis, Pneumonic D012766 3 associated lipids
Tracheal Diseases D014133 3 associated lipids
Treponemal Infections D014211 3 associated lipids
Neisseriaceae Infections D016870 3 associated lipids
Digital Dermatitis D058066 3 associated lipids
Dysentery D004403 4 associated lipids
Porcine Reproductive and Respiratory Syndrome D019318 4 associated lipids
Ureaplasma Infections D016869 5 associated lipids
Foreign Bodies D005547 5 associated lipids
Desulfovibrionaceae Infections D045824 5 associated lipids
Pyoderma D011711 5 associated lipids
Clostridium Infections D003015 5 associated lipids
Mycotoxicosis D015651 5 associated lipids
Pneumonia, Mycoplasma D011019 6 associated lipids
Liver Abscess D008100 6 associated lipids
Mycoplasmatales Infections D009180 6 associated lipids
Facial Dermatoses D005148 7 associated lipids
Bacteriuria D001437 7 associated lipids
Pasteurella Infections D010326 8 associated lipids
Lymphadenitis D008199 8 associated lipids
Staphylococcal Skin Infections D013207 9 associated lipids
Campylobacter Infections D002169 13 associated lipids
Mycoplasma Infections D009175 13 associated lipids
Vasculitis D014657 14 associated lipids
Swine Diseases D013553 16 associated lipids
Pneumonia, Bacterial D018410 16 associated lipids
Ataxia D001259 20 associated lipids
Poultry Diseases D011201 21 associated lipids
Bacterial Infections D001424 21 associated lipids
Cattle Diseases D002418 24 associated lipids
Diarrhea D003967 32 associated lipids
Hyperplasia D006965 34 associated lipids
Occupational Diseases D009784 42 associated lipids
Asthma D001249 52 associated lipids
Colitis D003092 69 associated lipids
Weight Gain D015430 101 associated lipids
Hemolysis D006461 131 associated lipids
Body Weight D001835 333 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Tylosin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Tylosin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Tylosin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Tylosin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Tylosin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Tylosin?

Knock-out

Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Tylosin

Download all related citations
Per page 10 20 50 100 | Total 931
Authors Title Published Journal PubMed Link
Cernicchiaro N et al. Meta-analysis of the effects of laidlomycin propionate, fed alone or in combination with chlortetracycline, compared with monensin sodium, fed alone or in combination with tylosin, on growth performance, health, and carcass outcomes in finishing steers in North America. 2016 J. Anim. Sci. pmid:27136025
Kim J et al. Effects of the Antibiotics Growth Promoter Tylosin on Swine Gut Microbiota. 2016 J. Microbiol. Biotechnol. pmid:26869601
Brown K et al. Antimicrobial growth promoters modulate host responses in mice with a defined intestinal microbiota. 2016 Sci Rep pmid:27929072
Cleary DW et al. Long-term antibiotic exposure in soil is associated with changes in microbial community structure and prevalence of class 1 integrons. 2016 FEMS Microbiol. Ecol. pmid:27495240
Molognoni L et al. Development of a LC-MS/MS method for the simultaneous determination of sorbic acid, natamycin and tylosin in Dulce de leche. 2016 Food Chem pmid:27283692
Canning P et al. Concentrations of tylvalosin and 3-O-acetyltylosin attained in the synovial fluid of swine after administration by oral gavage at 50 and 5 mg/kg. 2016 J. Vet. Pharmacol. Ther. pmid:27086612
Mendoza J et al. Concentrations of tilmicosin in mammary gland secretions of dairy cows following subcutaneous administration of one or two doses of an experimental preparation of tilmicosin and its efficacy against intramammary infections caused by Staphylococcus aureus. 2016 Am. J. Vet. Res. pmid:27580103
Kim E et al. Characterization of the Two Methylation Steps Involved in the Biosynthesis of Mycinose in Tylosin. 2016 J. Nat. Prod. pmid:27453999
Kline A and Pinckney JL Size-selective toxicity effects of the antimicrobial tylosin on estuarine phytoplankton communities. 2016 Environ. Pollut. pmid:27376985
Besserer F et al. Tilmicosin toxicity: a case of accidental human tilmicosin injection managed with calcium, high-dose insulin and intravenous lipid emulsion therapy. 2016 Clin Toxicol (Phila) pmid:27207720
Guo X et al. Sorption of tylosin and sulfamethazine on solid humic acid. 2016 J Environ Sci (China) pmid:27155426
Crepieux T et al. Randomized, non-inferiority trial comparing a nitric oxide releasing solution with a macrolide antibiotic for control of bovine respiratory disease in beef feedlot calves at high-risk of developing respiratory tract disease. 2016 Res. Vet. Sci. pmid:27033936
Confer AW et al. Clinical disease and lung lesions in calves experimentally inoculated with Histophilus somni five days after metaphylactic administration of tildipirosin or tulathromycin. 2016 Am. J. Vet. Res. pmid:27027834
Torres F et al. Pharmacokinetics of tildipirosin in pig tonsils. 2016 J. Vet. Pharmacol. Ther. pmid:26935349
El-Ela FI et al. Investigating the potential role of vitamin E in modulating the immunosuppressive effects of tylvalosin and florfenicol in broiler chickens. 2016 Res. Vet. Sci. pmid:27663366
Krokidis M et al. The slow dissociation rate of K-1602 contributes to the enhanced inhibitory activity of this novel alkyl-aryl-bearing fluoroketolide. 2016 J Enzyme Inhib Med Chem pmid:25807301
Amarakoon ID et al. Dissipation of Antimicrobials in a Seasonally Frozen Soil after Beef Cattle Manure Application. 2016 J. Environ. Qual. pmid:27695746
Whitehead TR and Cotta MA Examination of the Aerobic Microflora of Swine Feces and Stored Swine Manure. 2016 J. Environ. Qual. pmid:27065407
Amarakoon ID et al. Dissipation of Antimicrobials in Feedlot Manure Compost after Oral Administration versus Fortification after Excretion. 2016 J. Environ. Qual. pmid:27065397
García-Sánchez L et al. Tylosin effect on methanogenesis in an anaerobic biomass from swine wastewater treatment. 2016 Water Sci. Technol. pmid:26819401