Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.
To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Tylosin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Thomas E et al. | A field comparison of the efficacy and tolerance of marbofloxacin in the treatment of bovine respiratory disease. | 2001 | J. Vet. Pharmacol. Ther. | pmid:11696086 |
Draisci R et al. | A new electrochemical enzyme-linked immunosorbent assay for the screening of macrolide antibiotic residues in bovine meat. | 2001 | Analyst | pmid:11763071 |
Hoflack G et al. | Efficacy of tilmicosin phosphate (Pulmotil premix) in feed for the treatment of a clinical outbreak of Actinobacillus pleuropneumoniae infection in growing-finishing pigs. | 2001 | J. Vet. Med. B Infect. Dis. Vet. Public Health | pmid:11765801 |
Cundliffe E et al. | The tylosin-biosynthetic genes of Streptomyces fradiae. | 2001 | Antonie Van Leeuwenhoek | pmid:11816964 |
Prats C et al. | Determination of tylosin residues in different animal tissues by high performance liquid chromatography. | 2002 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:11820296 |
Zhang YX et al. | Genome shuffling leads to rapid phenotypic improvement in bacteria. | 2002 | Nature | pmid:11832946 |
Stratigopoulos G and Cundliffe E | Expression analysis of the tylosin-biosynthetic gene cluster: pivotal regulatory role of the tylQ product. | 2002 | Chem. Biol. | pmid:11841940 |
Mateusen B et al. | A comparative study of the preventive use of tilmicosin phosphate (Pulmotil premix) and Mycoplasma hyopneumoniae vaccination in a pig herd with chronic respiratory disease. | 2001 | J. Vet. Med. B Infect. Dis. Vet. Public Health | pmid:11846018 |
Saurit AR et al. | Some comparative aspects of the pharmacokinetics of tylosin in buffaloes and cattle. | 2002 | Vet. Res. Commun. | pmid:11860087 |
Brumm MC et al. | Effect of wean-to-finish management on pig performance. | 2002 | J. Anim. Sci. | pmid:11881920 |