Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.
To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Tylosin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Womble A et al. | Pulmonary disposition of tilmicosin in foals and in vitro activity against Rhodococcus equi and other common equine bacterial pathogens. | 2006 | J. Vet. Pharmacol. Ther. | pmid:17083461 |
Booker CW et al. | An evaluation of the metaphylactic effect of ceftiofur crystalline free Acid in feedlot calves. | 2006 | Vet. Ther. | pmid:17039449 |
MartÃnez MF and Barth AD | Early detection and treatment of vesicular adenitis in bulls. | 2007 | Anim. Reprod. Sci. | pmid:17027202 |
McAllister TA et al. | Shedding of escherichia coli O157:H7 by cattle fed diets containing monensin or tylosin. | 2006 | J. Food Prot. | pmid:16995508 |
Peng Z and Bang-Ce Y | Small molecule microarrays for drug residue detection in foodstuffs. | 2006 | J. Agric. Food Chem. | pmid:16968051 |
Bate N et al. | Regulation of tylosin biosynthesis involving 'SARP-helper' activity. | 2006 | Mol. Microbiol. | pmid:16942604 |
Industry guidance on the administration of tilmicosin. | 2006 | Vet. Rec. | pmid:16924727 | |
Chun S et al. | Influence of agricultural antibiotics and 17beta-estradiol on the microbial community of soil. | 2006 | J Environ Sci Health B | pmid:16893780 |
Residues of some veterinary drugs in animals and foods. Monographs prepared by the thirty-eighth meeting of the Joint FAO/WHO Expert Committee on Food Additives. | 1991 | FAO Food Nutr Pap | pmid:1687815 | |
Karahalios P et al. | On the mechanism of action of 9-O-arylalkyloxime derivatives of 6-O-mycaminosyltylonolide, a new class of 16-membered macrolide antibiotics. | 2006 | Mol. Pharmacol. | pmid:16873579 |
DiLorenzo N et al. | Effects of feeding polyclonal antibody preparations on ruminal bacterial populations and ruminal pH of steers fed high-grain diets. | 2006 | J. Anim. Sci. | pmid:16864880 |
Jiang H et al. | Residue depletion of tilmicosin in cattle after subcutaneous administration. | 2006 | J. Agric. Food Chem. | pmid:16819937 |
Allaire SE et al. | Sorption kinetics of chlortetracyline and tylosin on sandy loam and heavy clay soils. | 2006 Jul-Aug | J. Environ. Qual. | pmid:16738380 |
Yang S et al. | Trace analysis and occurrence of anhydroerythromycin and tylosin in influent and effluent wastewater by liquid chromatography combined with electrospray tandem mass spectrometry. | 2006 | Anal Bioanal Chem | pmid:16715282 |
GarcÃa-Mayor MA et al. | Liquid chromatography-UV diode-array detection method for multi-residue determination of macrolide antibiotics in sheep's milk. | 2006 | J Chromatogr A | pmid:16682049 |
Cao XY et al. | Tilmicosin and tylosin have anti-inflammatory properties via modulation of COX-2 and iNOS gene expression and production of cytokines in LPS-induced macrophages and monocytes. | 2006 | Int. J. Antimicrob. Agents | pmid:16647840 |
Dingwell RT et al. | Influence of the genotype of Staphylococcus aureus, determined by pulsed-field gel electrophoresis, on dry-period elimination of subclinical mastitis in Canadian dairy herds. | 2006 | Can. J. Vet. Res. | pmid:16639943 |
Terui Y et al. | Synthesis of 2-methyl 16-membered macrolide derived from tylosin. | 2006 | J. Antibiot. | pmid:16629410 |
ter Laak TL et al. | Estimation of soil sorption coefficients of veterinary pharmaceuticals from soil properties. | 2006 | Environ. Toxicol. Chem. | pmid:16629132 |
ter Laak TL et al. | The effect of pH and ionic strength on the sorption of sulfachloropyridazine, tylosin, and oxytetracycline to soil. | 2006 | Environ. Toxicol. Chem. | pmid:16629129 |
Shakeri-Nejad K and Stahlmann R | Drug interactions during therapy with three major groups of antimicrobial agents. | 2006 | Expert Opin Pharmacother | pmid:16556082 |
Nozal Nalda MJ et al. | Trace analysis of antibacterial tylosin A, B, C and D in honey by liquid chromatography-electrospray ionization-mass spectrometry. | 2006 | J Sep Sci | pmid:16544883 |
Carlson JC and Mabury SA | Dissipation kinetics and mobility of chlortetracycline, tylosin, and monensin in an agricultural soil in Northumberland County, Ontario, Canada. | 2006 | Environ. Toxicol. Chem. | pmid:16494218 |
Jung WS et al. | Heterologous expression of tylosin polyketide synthase and production of a hybrid bioactive macrolide in Streptomyces venezuelae. | 2006 | Appl. Microbiol. Biotechnol. | pmid:16493552 |
Jacobsen AM and Halling-Sørensen B | Multi-component analysis of tetracyclines, sulfonamides and tylosin in swine manure by liquid chromatography-tandem mass spectrometry. | 2006 | Anal Bioanal Chem | pmid:16485090 |
Chelliapan S et al. | Performance of an up-flow anaerobic stage reactor (UASR) in the treatment of pharmaceutical wastewater containing macrolide antibiotics. | 2006 | Water Res. | pmid:16387347 |
Westermarck E et al. | Effect of diet and tylosin on chronic diarrhea in beagles. | 2005 Nov-Dec | J. Vet. Intern. Med. | pmid:16355675 |
Fu H et al. | Synthesis and in vitro antibiotic activity of 16-membered 9-O-arylalkyloxime macrolides. | 2006 | Bioorg. Med. Chem. Lett. | pmid:16343900 |
Beier RC et al. | Production and characterization of monoclonal antibodies against the antibiotic tilmicosin. | 2005 | J. Agric. Food Chem. | pmid:16332115 |
Ayling RD et al. | Assessing the in vitro effectiveness of antimicrobials against Mycoplasma mycoides subsp. mycoides small-colony type to reduce contagious bovine pleuropneumonia infection. | 2005 | Antimicrob. Agents Chemother. | pmid:16304194 |
Jensen LB and Aarestrup FM | Regulation of the erm(C) gene in Staphylococci from reservoir with different usage of macrolides. | 2005 | Acta Vet. Scand. | pmid:16261929 |
Mathieson PW et al. | Mercuric chloride-treated brown Norway rats develop widespread tissue injury including necrotizing vasculitis. | 1992 | Lab. Invest. | pmid:1625442 |
Pringle M et al. | Tiamulin resistance in porcine Brachyspira pilosicoli isolates. | 2006 | Res. Vet. Sci. | pmid:16253666 |
Rozeboom DW et al. | Effects of mannan oligosaccharide and an antimicrobial product in nursery diets on performance of pigs reared on three different farms. | 2005 | J. Anim. Sci. | pmid:16230663 |
Kumar K et al. | Antibiotic uptake by plants from soil fertilized with animal manure. | 2005 Nov-Dec | J. Environ. Qual. | pmid:16221828 |
Chander Y et al. | Antibacterial activity of soil-bound antibiotics. | 2005 Nov-Dec | J. Environ. Qual. | pmid:16221813 |
Brumbaugh GW et al. | Effect of tilmicosin on chemotactic, phagocytic, and bactericidal activities of bovine and porcine alveolar macrophages. | 2002 | Am. J. Vet. Res. | pmid:16206777 |
Clay SA et al. | Tylosin sorption to silty clay loam soils, swine manure, and sand. | 2005 | J Environ Sci Health B | pmid:16194921 |
Chun S et al. | Effect of agricultural antibiotics on the persistence and transformation of 17beta-estradiol in a Sequatchie loam. | 2005 | J Environ Sci Health B | pmid:16190018 |
Caldow M et al. | Development and validation of an optical SPR biosensor assay for tylosin residues in honey. | 2005 | J. Agric. Food Chem. | pmid:16159159 |
Skogerboe TL et al. | Comparative efficacy of tulathromycin versus florfenicol and tilmicosin against undifferentiated bovine respiratory disease in feedlot cattle. | 2005 | Vet. Ther. | pmid:16094565 |
Nutsch RG et al. | Comparative efficacy of tulathromycin, tilmicosin, and florfenicol in the treatment of bovine respiratory disease in stocker cattle. | 2005 | Vet. Ther. | pmid:16094564 |
Rooney KA et al. | Efficacy of tulathromycin compared with tilmicosin and florfenicol for the control of respiratory disease in cattle at high risk of developing bovine respiratory disease. | 2005 | Vet. Ther. | pmid:16094563 |
Kilgore WR et al. | Therapeutic efficacy of tulathromycin, a novel triamilide antimicrobial, against bovine respiratory disease in feeder calves. | 2005 | Vet. Ther. | pmid:16094562 |
Kilgore WR et al. | Clinical effectiveness of tulathromycin, a novel triamilide antimicrobial, for the control of respiratory disease in cattle at high risk for developing bovine respiratory disease. | 2005 | Vet. Ther. | pmid:16094561 |
Godinho KS et al. | Efficacy of tulathromycin in the treatment and prevention of natural outbreaks of bovine respiratory disease in European cattle. | 2005 | Vet. Ther. | pmid:16094560 |
Patterson J et al. | Selected culturable enteric bacterial populations are modified by diet acidification and the growth promotant Tylosin. | 2005 | Lett. Appl. Microbiol. | pmid:16033507 |
Shen J et al. | Pharmacokinetics of tilmicosin after oral administration in swine. | 2005 | Am. J. Vet. Res. | pmid:16008233 |
Forrester MB | Human exposures to tilmicosin reported to poison centres, Texas, 1998-2003. | 2005 | Hum Exp Toxicol | pmid:16004193 |
Fang XM et al. | [A study on space mutation of Streptomyces fradiae]. | 2005 | Space Med Med Eng (Beijing) | pmid:15977391 |