Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.
To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Tylosin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Zhang L et al. | Pharmacokinetics of tilmicosin in healthy pigs and in pigs experimentally infected with . | 2017 | J. Vet. Sci. | pmid:28385011 |
Abell KM et al. | A mixed treatment comparison meta-analysis of metaphylaxis treatments for bovine respiratory disease in beef cattle. | 2017 | J. Anim. Sci. | pmid:28380607 |
Rodionova II et al. | [Effect of protoplast formation on the antibiotic activity of the Streptomyces fradiae 165 strain--a producer of tylosin]. | 1987 | Antibiot. Med. Biotekhnol. | pmid:2830838 |
Nowakiewicz A et al. | Determination of antimicrobial resistance of Enterococcus strains isolated from pigs and their genotypic characterization by method of amplification of DNA fragments surrounding rare restriction sites (ADSRRS fingerprinting). | 2017 | J. Med. Microbiol. | pmid:28260584 |
Timsit E et al. | Effects of nasal instillation of a nitric oxide-releasing solution or parenteral administration of tilmicosin on the nasopharyngeal microbiota of beef feedlot cattle at high-risk of developing respiratory tract disease. | 2017 | Res. Vet. Sci. | pmid:28231472 |
Ray P et al. | Fate and Effect of Antibiotics in Beef and Dairy Manure during Static and Turned Composting. | 2017 | J. Environ. Qual. | pmid:28177414 |
De Mil T et al. | Influence of mycotoxin binders on the oral bioavailability of tylosin, doxycycline, diclazuril, and salinomycin in fed broiler chickens. | 2017 | Poult. Sci. | pmid:28160001 |
Ball HJ and Campbell JN | Antibiotic treatment of experimental Mycoplasma californicum mastitis. | 1989 | Vet. Rec. | pmid:2815518 |
Hume ME and Donskey CJ | Effect of Vancomycin, Tylosin, and Chlortetracycline on Vancomycin-Resistant Enterococcus faecium Colonization of Broiler Chickens During Grow-Out. | 2017 | Foodborne Pathog. Dis. | pmid:28128649 |
Weber NR et al. | Batch medication of intestinal infections in nursery pigs-A randomised clinical trial on the efficacy of treatment strategy, type of antibiotic and bacterial load on average daily weight gain. | 2017 | Prev. Vet. Med. | pmid:28107883 |
Teixeira AGV et al. | Efficacy of tildipirosin metaphylaxis for the prevention of respiratory disease, otitis and mortality in pre-weaned Holstein calves. | 2017 | Vet. J. | pmid:28093111 |
Zhang N et al. | Determination of the Mutant Selection Window and Evaluation of the Killing of Mycoplasma gallisepticum by Danofloxacin, Doxycycline, Tilmicosin, Tylvalosin and Valnemulin. | 2017 | PLoS ONE | pmid:28052123 |
Kempf I et al. | [Efficacy of spiramycin and tylosin in preventing mycoplasmosis in chicks experimentally infected with mycoplasma gallisepticum]. | 1989 | Pathol. Biol. | pmid:2797880 |
Ruggeri C et al. | Synthesis and antibacterial activity of 9-O-[(2-methoxyethoxy)methyl]-oximes of tylosin and demycarosyltylosin. | 1989 | J. Antibiot. | pmid:2793598 |
Liu B et al. | Copper exposure to soil under single and repeated application: Selection for the microbial community tolerance and effects on the dissipation of antibiotics. | 2017 | J. Hazard. Mater. | pmid:27930997 |
Brown K et al. | Antimicrobial growth promoters modulate host responses in mice with a defined intestinal microbiota. | 2016 | Sci Rep | pmid:27929072 |
Bébrová E et al. | [Immunologic reactivity of tylosin and erythromycin]. | 1989 | Cesk Epidemiol Mikrobiol Imunol | pmid:2790978 |
Tereshchenkov AG et al. | New Fluorescent Macrolide Derivatives for Studying Interactions of Antibiotics and Their Analogs with the Ribosomal Exit Tunnel. | 2016 | Biochemistry Mosc. | pmid:27908240 |
Anti-infective drug use in relation to the risk of agranulocytosis and aplastic anemia. A report from the International Agranulocytosis and Aplastic Anemia Study. | 1989 | Arch. Intern. Med. | pmid:2785785 | |
Cheng J et al. | Microstructure and antioxidative capacity of the microalgae mutant Chlorella PY-ZU1 during tilmicosin removal from wastewater under 15% CO. | 2017 | J. Hazard. Mater. | pmid:27829514 |