Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.
To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Tylosin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Salamakha OV et al. | [The study of the growth of tylosin producer using differential centrifugation of mycelium in a sucrose density gradient]. | 1989 Sep-Oct | Mikrobiologiia | pmid:2635267 |
Matsushima P et al. | Transduction and transformation of plasmid DNA in Streptomyces fradiae strains that express different levels of restriction. | 1989 | J. Bacteriol. | pmid:2542216 |
Debono M et al. | Synthesis and antimicrobial evaluation of 20-deoxo-20-(3,5-dimethylpiperidin-1-yl)desmycosin (tilmicosin, EL-870) and related cyclic amino derivatives. | 1989 | J. Antibiot. | pmid:2668243 |
Zalacain M and Cundliffe E | Methylation of 23S rRNA caused by tlrA (ermSF), a tylosin resistance determinant from Streptomyces fradiae. | 1989 | J. Bacteriol. | pmid:2753855 |
Synek M et al. | [Immunologic aspects of macrolide antibiotics]. | 1989 | Cas. Lek. Cesk. | pmid:2731206 |
Ryoo JP et al. | Data acquisition and processing system for drug release characterization by thin layer chromatography. | 1989 | Biomed Sci Instrum | pmid:2742974 |
Marshall VP et al. | Enzymic inactivation of lincosaminide and macrolide antibiotics: divalent metal cation and coenzyme specificities. | 1989 | J. Antibiot. | pmid:2722691 |
de Zwart MA et al. | Synthesis and copper-dependent antimycoplasmal activity of 1-amino-3-(2-pyridyl)isoquinoline derivatives. 2. Amidines. | 1989 | J. Med. Chem. | pmid:2913309 |
Ball HJ and Campbell JN | Antibiotic treatment of experimental Mycoplasma californicum mastitis. | 1989 | Vet. Rec. | pmid:2815518 |
Yao RC and Mahoney DF | Enzyme immunoassay for macrolide antibiotics: characterization of an antibody to 23-amino-O-mycaminosyltylonolide. | 1989 | Appl. Environ. Microbiol. | pmid:2764563 |