Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.
To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with Tylosin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
---|
Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).
Model | Cross reference | Weighted score | Related literatures |
---|
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Rabølle M and Spliid NH | Sorption and mobility of metronidazole, olaquindox, oxytetracycline and tylosin in soil. | 2000 | Chemosphere | pmid:10705549 |
Guo X et al. | Sorption properties of tylosin on four different microplastics. | 2018 | Chemosphere | pmid:29933160 |
Stromer BS et al. | Tylosin sorption to diatomaceous earth described by Langmuir isotherm and Freundlich isotherm models. | 2018 | Chemosphere | pmid:29874766 |
Yin Y et al. | Iron and manganese oxides modified maize straw to remove tylosin from aqueous solutions. | 2018 | Chemosphere | pmid:29689529 |
Halling-Sørensen B | Algal toxicity of antibacterial agents used in intensive farming. | 2000 | Chemosphere | pmid:10705551 |
Grdisa M et al. | Effect of a 17-member azalide on tumor cell growth. | 1998 Sep-Oct | Chemotherapy | pmid:9732149 |
Besserer F et al. | Tilmicosin toxicity: a case of accidental human tilmicosin injection managed with calcium, high-dose insulin and intravenous lipid emulsion therapy. | 2016 | Clin Toxicol (Phila) | pmid:27207720 |
Blackwood RS et al. | Effects of the macrolide drug tylosin on chronic diarrhea in rhesus macaques (Macaca mulatta). | 2008 | Comp. Med. | pmid:19793461 |
Tuomi ML and Räsänen L | Contact allergy to tylosin and cobalt in a pig-farmer. | 1995 | Contact Derm. | pmid:8654098 |
Caraffini S et al. | Tylosin, an airborne contact allergen in veterinarians. | 1994 | Contact Derm. | pmid:7867337 |
Danese P et al. | Occupational contact dermatitis from tylosin. | 1994 | Contact Derm. | pmid:8187499 |
Whitehead TR and Cotta MA | Sequence analyses of a broad host-range plasmid containing ermT from a tylosin-resistant Lactobacillus sp. Isolated from swine feces. | 2001 | Curr. Microbiol. | pmid:11375658 |
Zhang AJ and Warshaw EM | Pet Consort Dermatitis: The Importance of Asking About Pets. | Dermatitis | pmid:29901502 | |
Malaiyandi V et al. | Airborne allergic contact dermatitis from tylosin in pharmacy compounders and cross-sensitization to macrolide antibiotics. | 2012 Sep-Oct | Dermatitis | pmid:23010831 |
Jung HD | [Occupationally-induced contact eczema by tylosin (Tylan)]. | 1983 | Dermatol Monatsschr | pmid:6222923 |
Song M et al. | The controlled release of tilmicosin from silica nanoparticles. | 2011 | Drug Dev Ind Pharm | pmid:21204738 |
Atef M et al. | Effect of albendazole administration on pharmacokinetic aspects of tylosin in lactating goats. | 2009 | Drug Metab Lett | pmid:19702546 |
Atef M et al. | Disposition of tylosin in goats. | 1991 | DTW. Dtsch. Tierarztl. Wochenschr. | pmid:1790764 |
Atef M et al. | Elimination of tilmicosin in lactating ewes. | 1999 | DTW. Dtsch. Tierarztl. Wochenschr. | pmid:10481373 |
el-Sayed MG et al. | Pharmacokinetic profile of tylosin in mastitic cows. | 1986 | DTW. Dtsch. Tierarztl. Wochenschr. | pmid:3530702 |