Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.
To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Tylosin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Besserer F et al. | Tilmicosin toxicity: a case of accidental human tilmicosin injection managed with calcium, high-dose insulin and intravenous lipid emulsion therapy. | 2016 | Clin Toxicol (Phila) | pmid:27207720 |
Guo X et al. | Sorption of tylosin and sulfamethazine on solid humic acid. | 2016 | J Environ Sci (China) | pmid:27155426 |
Cernicchiaro N et al. | Meta-analysis of the effects of laidlomycin propionate, fed alone or in combination with chlortetracycline, compared with monensin sodium, fed alone or in combination with tylosin, on growth performance, health, and carcass outcomes in finishing steers in North America. | 2016 | J. Anim. Sci. | pmid:27136025 |
Canning P et al. | Concentrations of tylvalosin and 3-O-acetyltylosin attained in the synovial fluid of swine after administration by oral gavage at 50 and 5Â mg/kg. | 2016 | J. Vet. Pharmacol. Ther. | pmid:27086612 |
Whitehead TR and Cotta MA | Examination of the Aerobic Microflora of Swine Feces and Stored Swine Manure. | 2016 | J. Environ. Qual. | pmid:27065407 |
Amarakoon ID et al. | Dissipation of Antimicrobials in Feedlot Manure Compost after Oral Administration versus Fortification after Excretion. | 2016 | J. Environ. Qual. | pmid:27065397 |
Crepieux T et al. | Randomized, non-inferiority trial comparing a nitric oxide releasing solution with a macrolide antibiotic for control of bovine respiratory disease in beef feedlot calves at high-risk of developing respiratory tract disease. | 2016 | Res. Vet. Sci. | pmid:27033936 |
Confer AW et al. | Clinical disease and lung lesions in calves experimentally inoculated with Histophilus somni five days after metaphylactic administration of tildipirosin or tulathromycin. | 2016 | Am. J. Vet. Res. | pmid:27027834 |
Torres F et al. | Pharmacokinetics of tildipirosin in pig tonsils. | 2016 | J. Vet. Pharmacol. Ther. | pmid:26935349 |
Luby EM et al. | Fate and transport of tylosin-resistant bacteria and macrolide resistance genes in artificially drained agricultural fields receiving swine manure. | 2016 | Sci. Total Environ. | pmid:26874610 |
Kim J et al. | Effects of the Antibiotics Growth Promoter Tylosin on Swine Gut Microbiota. | 2016 | J. Microbiol. Biotechnol. | pmid:26869601 |
Kirst HA et al. | Structure-activity studies of 20-deoxo-20-amino derivatives of tylosin-related macrolides. | 1989 | J. Antibiot. | pmid:2684947 |
GarcÃa-Sánchez L et al. | Tylosin effect on methanogenesis in an anaerobic biomass from swine wastewater treatment. | 2016 | Water Sci. Technol. | pmid:26819401 |
Entorf M et al. | Comparative erythromycin and tylosin susceptibility testing of streptococci from bovine mastitis. | 2016 | Vet. Microbiol. | pmid:26732695 |
Debono M et al. | Synthesis and antimicrobial evaluation of 20-deoxo-20-(3,5-dimethylpiperidin-1-yl)desmycosin (tilmicosin, EL-870) and related cyclic amino derivatives. | 1989 | J. Antibiot. | pmid:2668243 |
Xia X et al. | Proteomic analysis of tylosin-resistant Mycoplasma gallisepticum reveals enzymatic activities associated with resistance. | 2015 | Sci Rep | pmid:26584633 |
Rose M et al. | A microbiological assay to estimate the antimicrobial activity of parenteral tildipirosin against foodborne pathogens and commensals in the colon of beef cattle and pigs. | 2016 | J. Vet. Pharmacol. Ther. | pmid:26538405 |
Lu C et al. | Identification of novel tylosin analogues generated by a wblA disruption mutant of Streptomyces ansochromogenes. | 2015 | Microb. Cell Fact. | pmid:26525981 |
El-Mahmoudy A and Gheith I | The anti-nociceptive potential of tilmicosin against chemical-induced but not thermal-induced pain in mice. | 2016 | Int J Immunopathol Pharmacol | pmid:26519523 |
Sehati N et al. | Application of hollow fiber membrane mediated with titanium dioxide nanowire/reduced graphene oxide nanocomposite in preconcentration of clotrimazole and tylosin. | 2015 | J Chromatogr A | pmid:26477522 |