Tylosin
Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Tylosin?
Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (6)
- Proc. Natl. Acad. Sci. U.S.A. (2)
- Appl. Environ. Microbiol. (2)
- Others (6)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Tylosin
PubChem Associated disorders and diseases
What pathways are associated with Tylosin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Tylosin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Tylosin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Tylosin?
There are no associated biomedical information in the current reference collection.
What genes are associated with Tylosin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (9)
- Microbiology (Reading, Engl.) (3)
- Proc. Natl. Acad. Sci. U.S.A. (2)
- Others (13)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Tylosin?
Knock-out
Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with Tylosin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Solliec M et al. | Analysis of trimethoprim, lincomycin, sulfadoxin and tylosin in swine manure using laser diode thermal desorption-atmospheric pressure chemical ionization-tandem mass spectrometry. | 2014 | Talanta | pmid:25059125 |
| Chopra S et al. | Characterization of impurities in tylosin using dual liquid chromatography combined with ion trap mass spectrometry. | 2013 | Talanta | pmid:23598092 |
| Crown LA and Smith RB | Accidental veterinary antibiotic injection into a farm worker. | 1999 | Tenn Med | pmid:10474305 |
| Doak GA | Failure of antibiotics gentamicin, tylosin, lincomycin and spectinomycin (GTLS) to eliminate Mycoplasma bovis in artificially infected frozen bovine semen. | 2000 | Theriogenology | pmid:10990358 |
| Kim S | Failure of antibiotics gentamicin, tylosin, lincomycin and spectinomycin to eliminate Mycoplasma bovis in artificially infected frozen bovine semen. | 2000 | Theriogenology | pmid:10990359 |
| Rosenbusch RF | Failure of antibiotics gentamicin, tylosin, lincomycin and spectinomycin (GTLS) to eliminate Mycoplasma bovis in artificially infected frozen bovine semen. | 2000 | Theriogenology | pmid:10990360 |
| Thomas CB | Failure of antibiotics gentamicin, tylosin, lincomycin and spectinomycin (GTLS) to eliminate Mycoplasma bovis in artificially infected frozen bovine semen. | 2000 | Theriogenology | pmid:10990361 |
| Visser IJ et al. | Failure of antibiotics gentamycin, tylosin, lincomycin and spectinomycin to eliminate Mycoplasma bovis in artificially infected frozen bovine semen. | 1999 | Theriogenology | pmid:10728994 |
| Boissevain I | [Punishment after the fact]. | 2007 | Tijdschr Diergeneeskd | pmid:17939495 |
| Westerbeek JA and Jaartsveld FH | [Mycoplasma infection on a cattle farm]. | 1987 | Tijdschr Diergeneeskd | pmid:3603536 |
| Westermarck E and Wiberg M | Exocrine pancreatic insufficiency in the dog: historical background, diagnosis, and treatment. | 2012 | Top Companion Anim Med | pmid:23148848 |
| Devreese M et al. | An in vitro model using the IPEC-J2 cell line for efficacy and drug interaction testing of mycotoxin detoxifying agents. | 2013 | Toxicol In Vitro | pmid:23078954 |
| Gershon P and Howells RE | Synergy of four macrolide antibiotics with chloroquine against chloroquine-resistant Plasmodium falciparum in vitro. | 1986 | Trans. R. Soc. Trop. Med. Hyg. | pmid:3299891 |
| McGuigan MA | Human exposures to tilmicosin (MICOTIL). | 1994 | Vet Hum Toxicol | pmid:7975134 |
| Jordan WH et al. | A review of the toxicology of the antibiotic MICOTIL 300. | 1993 | Vet Hum Toxicol | pmid:8470360 |
| Donev B et al. | [Intramammary drug forms of neotil in treating mastitis during lactation]. | 1982 | Vet Med Nauki | pmid:7157656 |
| Dilov P et al. | [Comparative studies on the resorption, anti-anemic action and growth effect of FV-82 and dextrofer-100 on pigs]. | 1984 | Vet Med Nauki | pmid:6474828 |
| Dilov P et al. | [Toxicity, tolerance and blood concentrations of iron and tylosin with the use of preparation FV-82]. | 1983 | Vet Med Nauki | pmid:6623919 |
| Donev B et al. | [Toxicological studies of a combination of technical tylosin phosphate with bentonite (farmazin TB)]. | 1983 | Vet Med Nauki | pmid:6659350 |
| Hopper RJ and Miller ML | Efficacy of swine erysipelas vaccine given simultaneously with medicated rations. | 1981 | Vet Med Small Anim Clin | pmid:6916559 |
| Hartman EG and Geryl J | Comparison between the minimal inhibitory concentration of tilmicosin and oxytetracycline for bovine pneumonic Pasteurella haemolytica isolates. | 1993 | Vet Q | pmid:8122359 |
| Voeten AC and Litjens JB | The hygienic treatment of turkey eggs by dipping in an antibiotic and disinfectant solution. | 1982 | Vet Q | pmid:7112889 |
| Nagaraja TG and Lechtenberg KF | Liver abscesses in feedlot cattle. | 2007 | Vet. Clin. North Am. Food Anim. Pract. | pmid:17606156 |
| Barbour EK et al. | Impact of synergism of calcium phosphomycin/tylosin tartarate supplements on the performance of broilers in the Lebanon. | 2010 Jan-Mar | Vet. Ital. | pmid:20391366 |
| Short CR | Comparative pharmacokinetics--sorting the sheep from the goats. | 1999 | Vet. J. | pmid:10558834 |
| Taha AA et al. | Disposition kinetics of tylosin administered intravenously and intramuscularly in desert sheep and Nubian goats. | 1999 | Vet. J. | pmid:10558841 |
| Fodor L et al. | Efficacy evaluations of the use of oral tilmicosin in pneumonic calves. | 2000 | Vet. J. | pmid:10712808 |
| Montesissa C et al. | Metabolism of tilmicosin by rabbit liver microsomes and hepatocytes. | 2004 | Vet. J. | pmid:14623156 |
| Teixeira AGV et al. | Efficacy of tildipirosin metaphylaxis for the prevention of respiratory disease, otitis and mortality in pre-weaned Holstein calves. | 2017 | Vet. J. | pmid:28093111 |
| Kilpinen S et al. | Oral tylosin administration is associated with an increase of faecal enterococci and lactic acid bacteria in dogs with tylosin-responsive diarrhoea. | 2015 | Vet. J. | pmid:26049259 |
| Devreese M et al. | Interaction between tylosin and bentonite clay from a pharmacokinetic perspective. | 2012 | Vet. J. | pmid:22749117 |
| Mitchell JD et al. | In vitro pharmacodynamics of gamithromycin against Mycoplasma mycoides subspecies mycoides Small Colony. | 2013 | Vet. J. | pmid:23810743 |
| Wang XF et al. | Enhancement of antibacterial activity of tilmicosin against Staphylococcus aureus by solid lipid nanoparticles in vitro and in vivo. | 2012 | Vet. J. | pmid:21900026 |
| Marks SL and Kather EJ | Antimicrobial susceptibilities of canine Clostridium difficile and Clostridium perfringens isolates to commonly utilized antimicrobial drugs. | 2003 | Vet. Microbiol. | pmid:12742714 |
| Alippi AM et al. | In vitro and in vivo susceptibility of the honeybee bacterial pathogen Paenibacillus larvae subsp. larvae to the antibiotic tylosin. | 2005 | Vet. Microbiol. | pmid:15951140 |
| Stipkovits L et al. | A comparison of the effect of tiamulin hydrogen fumarate and tylosin tartrate on mycoplasmas of ruminants and some animal ureaplasmas. | 1984 | Vet. Microbiol. | pmid:6730305 |
| Reynaldi FJ et al. | Effectiveness of tilmicosin against Paenibacillus larvae, the causal agent of American Foulbrood disease of honeybees. | 2008 | Vet. Microbiol. | pmid:18539412 |
| Juntunen P et al. | Antimicrobial resistance in Campylobacter coli selected by tylosin treatment at a pig farm. | 2010 | Vet. Microbiol. | pmid:20684867 |
| Woolums AR et al. | Multidrug resistant Mannheimia haemolytica isolated from high-risk beef stocker cattle after antimicrobial metaphylaxis and treatment for bovine respiratory disease. | 2018 | Vet. Microbiol. | pmid:29981701 |
| Juntunen P et al. | Longitudinal on-farm study of the development of antimicrobial resistance in Campylobacter coli from pigs before and after danofloxacin and tylosin treatments. | 2011 | Vet. Microbiol. | pmid:21397412 |
| Blondeau JM et al. | Comparative minimum inhibitory and mutant prevention drug concentrations of enrofloxacin, ceftiofur, florfenicol, tilmicosin and tulathromycin against bovine clinical isolates of Mannheimia haemolytica. | 2012 | Vet. Microbiol. | pmid:22677482 |
| Prats-van der Ham M et al. | Molecular resistance mechanisms of Mycoplasma agalactiae to macrolides and lincomycin. | 2017 | Vet. Microbiol. | pmid:29102109 |
| Svartström O et al. | Characterization of Treponema spp. isolates from pigs with ear necrosis and shoulder ulcers. | 2013 | Vet. Microbiol. | pmid:23948134 |
| Gautier-Bouchardon AV et al. | In vitro development of resistance to enrofloxacin, erythromycin, tylosin, tiamulin and oxytetracycline in Mycoplasma gallisepticum, Mycoplasma iowae and Mycoplasma synoviae. | 2002 | Vet. Microbiol. | pmid:12119137 |
| Kucerova Z et al. | Antimicrobial susceptibility of Actinobacillus pleuropneumoniae isolates from clinical outbreaks of porcine respiratory diseases. | 2011 | Vet. Microbiol. | pmid:21316872 |
| Aarestrup FM and Friis NF | Antimicrobial susceptibility testing of Mycoplasma hyosynoviae isolated from pigs during 1968 to 1971 and during 1995 and 1996. | 1998 | Vet. Microbiol. | pmid:9646463 |
| Cornick NA | Tylosin and chlorotetracycline decrease the duration of fecal shedding of E. coli O157:H7 by swine. | 2010 | Vet. Microbiol. | pmid:20018464 |
| Aarestrup FM and Jensen NE | Susceptibility testing of Actinobacillus pleuropneumoniae in Denmark. Evaluation of three different media of MIC-determinations and tablet diffusion tests. | 1999 | Vet. Microbiol. | pmid:10063535 |
| Shryock TR et al. | Antimicrobial susceptibility of Moraxella bovis. | 1998 | Vet. Microbiol. | pmid:9646479 |
| Stipkovits L et al. | In vitro testing of the anti-mycoplasma effect of some anti-coccidial drugs. | 1987 | Vet. Microbiol. | pmid:3439016 |