Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.
To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Tylosin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Anti-infective drug use in relation to the risk of agranulocytosis and aplastic anemia. A report from the International Agranulocytosis and Aplastic Anemia Study. | 1989 | Arch. Intern. Med. | pmid:2785785 | |
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Buller NB and Hampson DJ | Antimicrobial susceptibility testing of Serpulina hyodysenteriae. | 1994 | Aust. Vet. J. | pmid:7945100 |
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Skelly BJ et al. | Prophylactic efficacy of 3-acetyl-4''-isovaleryl tylosin in a Mycoplasma gallisepticum-induced airsacculitis infection. | 1986 Jul-Sep | Avian Dis. | pmid:3767811 |
Cummings TS et al. | Effect of medicated feed on tracheal infection and population of Mycoplasma gallisepticum in chickens. | 1986 Jul-Sep | Avian Dis. | pmid:3767816 |
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Korshunova GA et al. | [Peptide derivatives of tylosin-related macrolides]. | 2007 Mar-Apr | Bioorg. Khim. | pmid:17476984 |
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Choi DB et al. | Effects of rapessed oil on activity of methylmalonyl-CoA carboxyltransferase in culture of Streptomyces fradiae. | 1998 | Biosci. Biotechnol. Biochem. | pmid:9648221 |
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Shimada T et al. | Effects of the antimicrobial tylosin on the microbial community structure of an anaerobic sequencing batch reactor. | 2011 | Biotechnol. Bioeng. | pmid:20830676 |
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Gollins WJ | Occupational asthma due to tylosin tartrate. | 1989 | Br J Ind Med | pmid:2611166 |
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Atef M et al. | Disposition of tylosin in goats. | 1991 May-Jun | Br. Vet. J. | pmid:1878767 |
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DOORNENBAL H | CLINICAL EVALUATION OF TYLOSIN AS A TREATMENT OF VIBRIONIC DYSENTERY IN SWINE. | 1965 | Can J Comp Med Vet Sci | pmid:14300858 |
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Abdel-Daim MM et al. | Synergistic protective role of mirazid (Commiphora molmol) and ascorbic acid against tilmicosin-induced cardiotoxicity in mice. | 2015 | Can. J. Physiol. Pharmacol. | pmid:25429612 |
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Scott DW et al. | Efficacy of tylosin tablets for the treatment of pyoderma due to Staphylococcus intermedius infection in dogs. | 1994 | Can. Vet. J. | pmid:7994702 |
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Van Donkersgoed J et al. | The effect of administering long-acting oxytetracycline and tilmicosin either by dart gun or by hand on injection site lesions and drug residues in beef cattle. | 1999 | Can. Vet. J. | pmid:12001341 |
Schunich OC et al. | A comparison of prophylactic efficacy of tilmicosin and a new formulation of oxytetracycline in feedlot calves. | 2002 | Can. Vet. J. | pmid:12001501 |
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Barth AD and Wood MR | The effect of streptomycin, oxytetracycline, tilmicosin and phenylbutazone on spermatogenesis in bulls. | 1998 | Can. Vet. J. | pmid:10051958 |
Jim GK et al. | A comparison of florfenicol and tilmicosin for the treatment of undifferentiated fever in feedlot calves in western Canada. | 1999 | Can. Vet. J. | pmid:10086218 |