Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.
To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with Tylosin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
---|
Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).
Model | Cross reference | Weighted score | Related literatures |
---|
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Davies R and Roberts TA | Antimicrobial susceptibility of enterococci recovered from commercial swine carcasses: effect of feed additives. | 1999 | Lett. Appl. Microbiol. | pmid:10664974 |
Short CR | Comparative pharmacokinetics--sorting the sheep from the goats. | 1999 | Vet. J. | pmid:10558834 |
Taha AA et al. | Disposition kinetics of tylosin administered intravenously and intramuscularly in desert sheep and Nubian goats. | 1999 | Vet. J. | pmid:10558841 |
Baltadzhieva D et al. | [Analysis of immunological indices of occupational sensibilization to tylosin]. | 1999 | Med Tr Prom Ekol | pmid:10605285 |
Henderson JP and Ball HJ | Polyarthritis due to Mycoplasma bovis infection in adult dairy cattle in Northern Ireland. | 1999 | Vet. Rec. | pmid:10573196 |
Mandić Z et al. | Tylosin derivatives. V. Electrochemical opening of oxirane ring. | 1999 | J. Antibiot. | pmid:10695679 |
Visser IJ et al. | Failure of antibiotics gentamycin, tylosin, lincomycin and spectinomycin to eliminate Mycoplasma bovis in artificially infected frozen bovine semen. | 1999 | Theriogenology | pmid:10728994 |
Butler AR et al. | Impact of thioesterase activity on tylosin biosynthesis in Streptomyces fradiae. | 1999 | Chem. Biol. | pmid:10322123 |
Naranda A and Lopotar N | New derivatives of tylosin. IV. Dihydro and tetrahydro desmycosin oximes. | 1999 | J. Antibiot. | pmid:10092201 |
Owens WE et al. | Efficacy of parenterally or intramammarily administered tilmicosin or ceftiofur against Staphylococcus aureus mastitis during lactation. | 1999 | J. Dairy Sci. | pmid:10194686 |
Karlsson M et al. | Genetic basis of macrolide and lincosamide resistance in Brachyspira (Serpulina) hyodysenteriae. | 1999 | FEMS Microbiol. Lett. | pmid:10188254 |
Jim GK et al. | A comparison of florfenicol and tilmicosin for the treatment of undifferentiated fever in feedlot calves in western Canada. | 1999 | Can. Vet. J. | pmid:10086218 |
Crown LA and Smith RB | Accidental veterinary antibiotic injection into a farm worker. | 1999 | Tenn Med | pmid:10474305 |
Atef M et al. | Elimination of tilmicosin in lactating ewes. | 1999 | DTW. Dtsch. Tierarztl. Wochenschr. | pmid:10481373 |
Tobback K et al. | Micellar electrokinetic capillary chromatography of macrolide antibiotics. Separation of tylosin, erythromycin and their related substances. | 1999 | J Chromatogr A | pmid:10536850 |
Bate N et al. | Multiple regulatory genes in the tylosin biosynthetic cluster of Streptomyces fradiae. | 1999 | Chem. Biol. | pmid:10467127 |
Nagaraja TG et al. | Effects of tylosin on concentrations of Fusobacterium necrophorum and fermentation products in the rumen of cattle fed a high-concentrate diet. | 1999 | Am. J. Vet. Res. | pmid:10490072 |
Diarra MS et al. | Postantibiotic and physiological effects of tilmicosin, tylosin, and apramycin at subminimal and suprainhibitory concentrations on some swine and bovine respiratory tract pathogens. | 1999 | Int. J. Antimicrob. Agents | pmid:10461841 |
Scorneaux B and Shryock TR | Intracellular accumulation, subcellular distribution, and efflux of tilmicosin in bovine mammary, blood, and lung cells. | 1999 | J. Dairy Sci. | pmid:10386306 |
Wilson VT and Cundliffe E | Molecular analysis of tlrB, an antibiotic-resistance gene from tylosin-producing Streptomyces fradiae, and discovery of a novel resistance mechanism. | 1999 | J. Antibiot. | pmid:10348045 |