Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.
To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Tylosin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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De Liguoro M et al. | Determination of tylosin residues in pig tissues using high-performance liquid chromatography. | 1998 | Analyst | pmid:9764508 |
Nagaraja TG and Chengappa MM | Liver abscesses in feedlot cattle: a review. | 1998 | J. Anim. Sci. | pmid:9464910 |
Oh TG et al. | Induction of ermAMR from a clinical strain of Enterococcus faecalis by 16-membered-ring macrolide antibiotics. | 1998 | J. Bacteriol. | pmid:9791136 |
Berque I et al. | [Stereoselective synthesis of biologically active macrolides. Total synthesis of tylosine]. | 1998 | Ann Pharm Fr | pmid:9770007 |
Scorneaux B and Shryock TR | Intracellular accumulation, subcellular distribution, and efflux of tilmicosin in chicken phagocytes. | 1998 | Poult. Sci. | pmid:9776059 |
Scorneaux B and Shryock TR | Intracellular accumulation, subcellular distribution and efflux of tilmicosin in swine phagocytes. | 1998 | J. Vet. Pharmacol. Ther. | pmid:9731947 |
Aarestrup FM and Friis NF | Antimicrobial susceptibility testing of Mycoplasma hyosynoviae isolated from pigs during 1968 to 1971 and during 1995 and 1996. | 1998 | Vet. Microbiol. | pmid:9646463 |
Wilson VT and Cundliffe E | Characterization and targeted disruption of a glycosyltransferase gene in the tylosin producer, Streptomyces fradiae. | 1998 | Gene | pmid:9651492 |
Gotoh Y et al. | Chemical transformation of tylosin derivatives into neutral macrolides having a 3'-methoxyl group. | 1998 | Carbohydr. Res. | pmid:9720235 |
Vogel GJ et al. | Effects of tilmicosin on acute undifferentiated respiratory tract disease in newly arrived feedlot cattle. | 1998 | J. Am. Vet. Med. Assoc. | pmid:9638194 |
Barth AD and Wood MR | The effect of streptomycin, oxytetracycline, tilmicosin and phenylbutazone on spermatogenesis in bulls. | 1998 | Can. Vet. J. | pmid:10051958 |
Kempf I et al. | Efficacy of tilmicosin in the control of experimental Mycoplasma gallisepticum infection in chickens. | 1997 Oct-Dec | Avian Dis. | pmid:9454912 |
Readnour RS et al. | Liquid chromatographic determination of tilmicosin in swine feed at 200-400 mg/kg level: interlaboratory study. | 1997 Nov-Dec | J AOAC Int | pmid:9419853 |
Readnour RS et al. | Determination of tilmicosin in swine feeds by liquid chromatography. | 1997 Nov-Dec | J AOAC Int | pmid:9419854 |
Moran JW et al. | Determination of tilmicosin in bovine and porcine sera by liquid chromatography. | 1997 Nov-Dec | J AOAC Int | pmid:9419857 |
Yeh WK | Evolving enzyme technology for pharmaceutical applications: case studies. | 1997 Nov-Dec | J. Ind. Microbiol. Biotechnol. | pmid:9451830 |
Ramadan A | Pharmacokinetics of tilmicosin in serum and milk of goats. | 1997 Jan-Feb | Res. Vet. Sci. | pmid:9160424 |
Residues of some veterinary drugs in animals and foods. Monographs prepared by the Forty-Seventh meeting of the Joint FAO/WHO Expert Committee on Food Additives. Rome, 4-13 June 1996. | 1997 | FAO Food Nutr Pap | pmid:9253593 | |
Mironov VA et al. | [Effect of Ca2+ ions on biosynthesis and component composition of tylosin in Streptomyces fradiae]. | 1997 | Antibiot. Khimioter. | pmid:9182505 |
McFarland JW et al. | Quantitative structure-activity relationships among macrolide antibacterial agents: in vitro and in vivo potency against Pasteurella multocida. | 1997 | J. Med. Chem. | pmid:9135031 |