Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.
To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Tylosin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Navashin SM et al. | [Genetic and biochemical control of biosynthesis of macrolide antibiotics]. | 1990 | Antibiot. Khimioter. | pmid:2078074 |
Tikhomirova LA et al. | [Cytomorphological and cultural characteristics of tylosin-producing strains with different antibiotic activity]. | 1991 | Antibiot. Khimioter. | pmid:1755702 |
Panfilova ZI et al. | [Obtaining of mutants of Streptomyces fradiae producing tylosin by action of nitrosomethylurea on synchronously germinating spores]. | 1990 | Antibiot. Khimioter. | pmid:2383150 |
Esipov SE | [Novel mathematical approach to determination of antibiotics concentration by agar diffusion method. Analysis of graphical, table and mathematical options of relative biological activity estimation]. | 1998 | Antibiot. Khimioter. | pmid:9606490 |
Malanicheva IA et al. | [Protoplast fusion in Streptomyces fradiae strains producing neomycin and tylosin]. | 1992 | Antibiot. Khimioter. | pmid:1296531 |
Pai MP et al. | Macrolide drug interactions: an update. | 2000 | Ann Pharmacother | pmid:10772438 |
Berque I et al. | [Stereoselective synthesis of biologically active macrolides. Total synthesis of tylosine]. | 1998 | Ann Pharm Fr | pmid:9770007 |
Kawai K et al. | Antimicrobial susceptibilities of Mycoplasma isolated from bovine mastitis in Japan. | 2014 | Anim. Sci. J. | pmid:24261609 |
MartÃnez MF and Barth AD | Early detection and treatment of vesicular adenitis in bulls. | 2007 | Anim. Reprod. Sci. | pmid:17027202 |
Parker RM and Patel RK | Determination of tilmicosin in ovine milk using high-performance liquid chromatography. | 1994 | Analyst | pmid:7879857 |
Delepine B et al. | Identification of tylosin in bovine muscle at the maximum residue limit level by liquid chromatography-mass spectrometry, using a particle beam interface. | 1994 | Analyst | pmid:7879883 |
De Liguoro M et al. | Determination of tylosin residues in pig tissues using high-performance liquid chromatography. | 1998 | Analyst | pmid:9764508 |
Ammida NH et al. | Analysis of erythromycin and tylosin in bovine muscle using disposable screen printed electrodes. | 2004 | Analyst | pmid:14737577 |
Draisci R et al. | A new electrochemical enzyme-linked immunosorbent assay for the screening of macrolide antibiotic residues in bovine meat. | 2001 | Analyst | pmid:11763071 |
Zheng Y et al. | Molecularly imprinted solid-phase extraction for determination of tilmicosin in feed using high performance liquid chromatography. | 2011 | Anal. Chim. Acta | pmid:21435486 |
Bohm DA et al. | Preparation and characterisation of in-house reference material of tylosin in honey and results of a proficiency test. | 2011 | Anal. Chim. Acta | pmid:21742117 |
Thompson TS et al. | Degradation of incurred tylosin to desmycosin--implications for residue analysis of honey. | 2007 | Anal. Chim. Acta | pmid:17386728 |
Jacobsen AM and Halling-Sørensen B | Multi-component analysis of tetracyclines, sulfonamides and tylosin in swine manure by liquid chromatography-tandem mass spectrometry. | 2006 | Anal Bioanal Chem | pmid:16485090 |
Yang S et al. | Trace analysis and occurrence of anhydroerythromycin and tylosin in influent and effluent wastewater by liquid chromatography combined with electrospray tandem mass spectrometry. | 2006 | Anal Bioanal Chem | pmid:16715282 |
Moore GM et al. | Efficacy dose determination study of tilmicosin phosphate in feed for control of pneumonia caused by Actinobacillus pleuropneumoniae in swine. | 1996 | Am. J. Vet. Res. | pmid:8633812 |