Tylosin

Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Tylosin?

Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Tylosin

MeSH term MeSH ID Detail
Digital Dermatitis D058066 3 associated lipids
Bovine Respiratory Disease Complex D048090 2 associated lipids
Pneumonia of Calves, Enzootic D048089 2 associated lipids
Desulfovibrionaceae Infections D045824 5 associated lipids
Pneumonia of Swine, Mycoplasmal D045729 2 associated lipids
Porcine Reproductive and Respiratory Syndrome D019318 4 associated lipids
Primate Diseases D018419 2 associated lipids
Pneumonia, Bacterial D018410 16 associated lipids
Neisseriaceae Infections D016870 3 associated lipids
Ureaplasma Infections D016869 5 associated lipids
Bacillaceae Infections D016863 1 associated lipids
Mycotoxicosis D015651 5 associated lipids
Weight Gain D015430 101 associated lipids
Vasculitis D014657 14 associated lipids
Treponemal Infections D014211 3 associated lipids
Tracheal Diseases D014133 3 associated lipids
Swine Diseases D013553 16 associated lipids
Staphylococcal Skin Infections D013207 9 associated lipids
Pasteurellosis, Pneumonic D012766 3 associated lipids
Pyoderma D011711 5 associated lipids
Poultry Diseases D011201 21 associated lipids
Pneumonia, Mycoplasma D011019 6 associated lipids
Pasteurella Infections D010326 8 associated lipids
Occupational Diseases D009784 42 associated lipids
Mycoplasmatales Infections D009180 6 associated lipids
Mycoplasma Infections D009175 13 associated lipids
Lymphadenitis D008199 8 associated lipids
Liver Abscess D008100 6 associated lipids
Keratoconjunctivitis, Infectious D007639 2 associated lipids
Hyperplasia D006965 34 associated lipids
Hemolysis D006461 131 associated lipids
Foreign Bodies D005547 5 associated lipids
Facial Dermatoses D005148 7 associated lipids
Erysipelothrix Infections D004889 1 associated lipids
Enterotoxemia D004767 1 associated lipids
Dysentery D004403 4 associated lipids
Diarrhea D003967 32 associated lipids
Conjunctivitis, Viral D003236 1 associated lipids
Colitis D003092 69 associated lipids
Clostridium Infections D003015 5 associated lipids
Cattle Diseases D002418 24 associated lipids
Campylobacter Infections D002169 13 associated lipids
Body Weight D001835 333 associated lipids
Bacteriuria D001437 7 associated lipids
Bacterial Infections D001424 21 associated lipids
Ataxia D001259 20 associated lipids
Asthma D001249 52 associated lipids
Per page 10 20 50 | Total 47

PubChem Associated disorders and diseases

What pathways are associated with Tylosin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Tylosin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Tylosin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Tylosin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Tylosin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Tylosin?

Knock-out

Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Tylosin

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Per page 10 20 50 100 | Total 931
Authors Title Published Journal PubMed Link
Hartman EG and Geryl J Comparison between the minimal inhibitory concentration of tilmicosin and oxytetracycline for bovine pneumonic Pasteurella haemolytica isolates. 1993 Vet Q pmid:8122359
Takhirov MT et al. [Determination of tylosin in the water supply using a chromatographic method]. 1993 Gig Sanit pmid:8244081
Tanner AC et al. Adaptation of the Sensititre broth microdilution technique to antimicrobial susceptibility testing of Mycoplasma hyopneumoniae. 1993 Vet. Microbiol. pmid:8273275
Stephens CP et al. In-vitro antibacterial properties of tilmicosin against Australian isolates of Pasteurella multocida and Pasteurella haemolytica from cattle. 1993 Aust. Vet. J. pmid:8257321
Westermarck E et al. Effect of treatment on the jejunal and colonic bacterial flora of dogs with exocrine pancreatic insufficiency. 1993 Pancreas pmid:8302792
Cooper AC et al. In vitro activity of danofloxacin, tylosin and oxytetracycline against mycoplasmas of veterinary importance. 1993 Res. Vet. Sci. pmid:8393208
Huang SL et al. Purification and properties of NADPH-dependent tylosin reductase from Streptomyces fradiae. 1993 J. Biol. Chem. pmid:8360186
Binder S et al. [The effectiveness of tilmicosin in respiratory diseases of swine]. 1993 Berl. Munch. Tierarztl. Wochenschr. pmid:8431202
Cester CC et al. Effect of stage of oestrous cycle on tylosin disposition in genital tract secretions of cows. 1993 Res. Vet. Sci. pmid:8434145
Jordan FT et al. A comparison of the efficacy of danofloxacin and tylosin in the control of Mycoplasma gallisepticum infection in broiler chicks. 1993 J. Vet. Pharmacol. Ther. pmid:8386777
Meisel ML et al. Tylosin inhibits the steroidogenesis in mouse Leydig cells "in vitro". 1993 Life Sci. pmid:8390595
Kageyama S et al. Synthesis of 3-deoxy-3,4-didehydro derivatives of 5-O-mycaminosyltylonolide, 5-O-(4-deoxymycaminosyl) tylonolide, and desmycosin. 1993 J. Antibiot. pmid:8407589
Roets E et al. Quantitative analysis of tylosin by column liquid chromatography. 1993 J. Chromatogr. pmid:8445000
Danielson ND et al. Simple methods for the qualitative identification and quantitative determination of macrolide antibiotics. 1993 J Pharm Biomed Anal pmid:8504183
Lee SH and Lee KJ Aspartate aminotransferase and tylosin biosynthesis in Streptomyces fradiae. 1993 Appl. Environ. Microbiol. pmid:8481008
Morck DW et al. Prophylactic efficacy of tilmicosin for bovine respiratory tract disease. 1993 J. Am. Vet. Med. Assoc. pmid:8428833
Arisawa A et al. Cloning and nucleotide sequences of two genes involved in the 4''-O-acylation of macrolide antibiotics from Streptomyces thermotolerans. 1993 Biosci. Biotechnol. Biochem. pmid:7764361
Riddell KP et al. Antibiotic treatment of bovine embryos. 1993 J. Assist. Reprod. Genet. pmid:8069094
Clary EM et al. Supplemental fat and ionophores in finishing diets: feedlot performance and ruminal digesta kinetics in steers. 1993 J. Anim. Sci. pmid:8270535
Chuard C et al. In-vitro and in-vivo evaluation of the antistaphylococcal activity of S-5556, a new 16-membered macrolide. 1992 J. Antimicrob. Chemother. pmid:1452498
Kádár-Pauncz J et al. Isolation and structure elucidation of new antibiotics related to angolamycin. 1992 J. Antibiot. pmid:1399843
Kageyama S et al. Synthesis of 3,4'-dideoxymycaminosyl tylonolide, a novel type of macrolide derivative. 1992 J. Antibiot. pmid:1548187
Mathieson PW et al. Mercuric chloride-treated brown Norway rats develop widespread tissue injury including necrotizing vasculitis. 1992 Lab. Invest. pmid:1625442
Arzey GG and Arzey KE Successful treatment of mycoplasmosis in layer chickens with single dose therapy. 1992 Aust. Vet. J. pmid:1379426
Kempf I et al. Efficacy of danofloxacin in the therapy of experimental mycoplasmosis in chicks. 1992 Res. Vet. Sci. pmid:1332154
Malanicheva IA et al. [Protoplast fusion in Streptomyces fradiae strains producing neomycin and tylosin]. 1992 Antibiot. Khimioter. pmid:1296531
Baltz RH et al. Transposition of Tn5096 and related transposons in Streptomyces species. 1992 Gene pmid:1319378
Brahimi-Horn MC et al. Synthesis of hydrolytic enzymes during production of tylosin by Streptomyces fradiae. 1992 J. Ind. Microbiol. pmid:1381591
Gummow B et al. The diagnosis and treatment of bovine genital ureaplasmosis: a case study. 1992 J S Afr Vet Assoc pmid:1404223
Chin NX and Neu HC In vitro activity of MC-352, a new 16-membered macrolide. 1992 Antimicrob. Agents Chemother. pmid:1416853
Galyean ML et al. Performance of feedlot steers fed diets containing laidlomycin propionate or monensin plus tylosin, and effects of laidlomycin propionate concentration on intake patterns and ruminal fermentation in beef steers during adaptation to a high-concentrate diet. 1992 J. Anim. Sci. pmid:1429270
Atef M et al. Disposition of tylosin in goats. 1991 May-Jun Br. Vet. J. pmid:1878767
Nakura H et al. Formation of an antibacterial metabolite from a new macrolide compound 23-O-benzyl-5-mycaminosyl-tylonolide (TMC-101), by a hepatic microsomal drug-metabolizing enzyme system. 1991 J. Pharmacobio-dyn. pmid:1802985
Rezanka T et al. Isobutyrate as a precursor of n-butyrate in the biosynthesis of tylosine and fatty acids. 1991 FEMS Microbiol. Lett. pmid:1769552
Rosteck PR et al. Homology between proteins controlling Streptomyces fradiae tylosin resistance and ATP-binding transport. 1991 Gene pmid:1864505
Lee SH and Lee KJ Relationship between threonine dehydratase and biosynthesis of tylosin in Streptomyces fradiae. 1991 J. Gen. Microbiol. pmid:1783901
Atef M et al. Disposition of tylosin in goats. 1991 DTW. Dtsch. Tierarztl. Wochenschr. pmid:1790764
Hue KK and Bechhofer DH Effect of ermC leader region mutations on induced mRNA stability. 1991 J. Bacteriol. pmid:1711026
Tikhomirova LA et al. [Cytomorphological and cultural characteristics of tylosin-producing strains with different antibiotic activity]. 1991 Antibiot. Khimioter. pmid:1755702
Residues of some veterinary drugs in animals and foods. Monographs prepared by the thirty-eighth meeting of the Joint FAO/WHO Expert Committee on Food Additives. 1991 FAO Food Nutr Pap pmid:1687815
Zalacain M and Cundliffe E Cloning of tlrD, a fourth resistance gene, from the tylosin producer, Streptomyces fradiae. 1991 Gene pmid:1995426
Dzapo V and Reiner G [The nutritive effect of avilamycin in swine breeding and fattening]. 1991 DTW. Dtsch. Tierarztl. Wochenschr. pmid:1954859
Catchpole I and Dyke KG Replication mutants of Staphylococcus aureus macrolide-lincosamide-streptogramin B resistance plasmid pT48. 1991 Mol. Microbiol. pmid:1906970
Smith SC et al. In-vitro antimicrobial susceptibility of Australian isolates of Treponema hyodysenteriae. 1991 Aust. Vet. J. pmid:1839652
Schumann FJ et al. Prophylactic medication of feedlot calves with tilmicosin. 1991 Vet. Rec. pmid:2038809
Laven R and Andrews AH Long-acting antibiotic formulations in the treatment of calf pneumonia: a comparative study of tilmicosin and oxytetracycline. 1991 Vet. Rec. pmid:1926728
de Zwart MA et al. Synthesis and copper-dependent antimycoplasmal activity of amides and amidines derived from 2-amino-1,10-phenanthroline. 1991 J. Med. Chem. pmid:2002460
Picavet T et al. Efficacy of tilmicosin in treatment of pulmonary infections in calves. 1991 Vet. Rec. pmid:1837391
Mee JF and O'Farrell K Tilmicosin and calf pneumonia. 1991 Vet. Rec. pmid:1858280
Coleman MR and Mowrey DH Turbidimetric assay of tylosin in animal feeds containing urea. 1990 Nov-Dec J Assoc Off Anal Chem pmid:2289924