Tylosin
Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Tylosin?
Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (6)
- Appl. Environ. Microbiol. (2)
- Proc. Natl. Acad. Sci. U.S.A. (2)
- Others (6)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Tylosin
PubChem Associated disorders and diseases
What pathways are associated with Tylosin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Tylosin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Tylosin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Tylosin?
There are no associated biomedical information in the current reference collection.
What genes are associated with Tylosin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (9)
- Microbiology (Reading, Engl.) (3)
- Proc. Natl. Acad. Sci. U.S.A. (2)
- Others (13)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Tylosin?
Knock-out
Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with Tylosin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Lu L et al. | Autoinducer 2-like activity in poultry-associated enteric bacteria in response to subtherapeutic antibiotic exposure. | 2005 | Avian Dis. | pmid:15839416 |
| Migaki TT et al. | Efficacy of danofloxacin and tylosin in the control of mycoplasmosis in chicks infected with tylosin-susceptible or tylosin-resistant field isolates of Mycoplasma gallisepticum. | 1993 Apr-Jun | Avian Dis. | pmid:8395803 |
| Tanner AC et al. | A comparison of danofloxacin and tylosin in the control of induced Mycoplasma gallisepticum infection in broiler chicks. | 1993 Apr-Jun | Avian Dis. | pmid:8395804 |
| Jordan FT and Horrocks BK | The minimum inhibitory concentration of tilmicosin and tylosin for mycoplasma gallisepticum and Mycoplasma synoviae and a comparison of their efficacy in the control of Mycoplasma gallisepticum infection in broiler chicks. | 1996 Apr-Jun | Avian Dis. | pmid:8790882 |
| Carpenter TE et al. | The effect of Mycoplasma meleagridis infection and egg dipping on the weight-gain performance of turkey poults. | 1982 Apr-Jun | Avian Dis. | pmid:7103888 |
| Mathers JJ et al. | Inhibition of resistance plasmid transfer in Escherichia coli by ionophores, chlortetracycline, bacitracin, and ionophore/antimicrobial combinations. | 2004 Apr-Jun | Avian Dis. | pmid:15283418 |
| Crespo R and McMillan R | Facial cellulitis induced in chickens by Mycoplasma gallisepticum bacterin and its treatment. | 2008 | Avian Dis. | pmid:19166067 |
| Beltran-Alcrudo D et al. | A persistent outbreak of ulcerative enteritis in bobwhite quail (Colinus virginianus). | 2008 | Avian Dis. | pmid:18939648 |
| Jordan FT et al. | The comparison of an aqueous preparation of tilmicosin with tylosin in the treatment of Mycoplasma gallisepticum infection of turkey poults. | 1999 Jul-Sep | Avian Dis. | pmid:10494422 |
| Evans RD et al. | Field evaluation of tylosin premix in layers previously vaccinated with a live Mycoplasma gallisepticum vaccine. | 2002 Jan-Mar | Avian Dis. | pmid:11922337 |
| Cerdá RO et al. | In vitro antibiotic susceptibility of field isolates of Mycoplasma synoviae in Argentina. | 2002 Jan-Mar | Avian Dis. | pmid:11922338 |
| Luo H et al. | Identification of ribosomal RNA methyltransferase gene ermF in Riemerella anatipestifer. | 2015 | Avian Pathol. | pmid:25690020 |
| Forrester CA et al. | Mycoplasma gallisepticum in pheasants and the efficacy of tylvalosin to treat the disease. | 2011 | Avian Pathol. | pmid:22107092 |
| Binder S et al. | [The effectiveness of tilmicosin in respiratory diseases of swine]. | 1993 | Berl. Munch. Tierarztl. Wochenschr. | pmid:8431202 |
| Vissiennon T et al. | Effect of avilamycin, tylosin and ionophore anticoccidials on Clostridium perfringens enterotoxaemia in chickens. | 2000 | Berl. Munch. Tierarztl. Wochenschr. | pmid:10684178 |
| Omura S et al. | Biosynthesis of tylosin: oxidations of 5-O-mycaminosylprotylonolide at C-20 and C-23 with a cell-free extract from Streptomyces fradiae. | 1982 | Biochem. Biophys. Res. Commun. | pmid:7126228 |
| Zhao Z et al. | Tylvalosin exhibits anti-inflammatory property and attenuates acute lung injury in different models possibly through suppression of NF-κB activation. | 2014 | Biochem. Pharmacol. | pmid:24792436 |
| Dinos GP and Kalpaxis DL | Kinetic studies on the interaction between a ribosomal complex active in peptide bond formation and the macrolide antibiotics tylosin and erythromycin. | 2000 | Biochemistry | pmid:10995229 |
| Makarov GI et al. | Structural Insight into Interaction between C20 Phenylalanyl Derivative of Tylosin and Ribosomal Tunnel. | 2017 | Biochemistry Mosc. | pmid:28941460 |
| Sumbatyan NV et al. | Peptide derivatives of antibiotics tylosin and desmycosin, protein synthesis inhibitors. | 2003 | Biochemistry Mosc. | pmid:14616087 |