Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.
To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Tylosin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Salamakha OV et al. | [The study of the growth of tylosin producer using differential centrifugation of mycelium in a sucrose density gradient]. | 1989 Sep-Oct | Mikrobiologiia | pmid:2635267 |
Cacciapuoti AF et al. | Microbiological and pharmacokinetic studies of acyl demycinosyltylosin and related tylosin derivatives. | 1990 | J. Antibiot. | pmid:2145254 |
Navashin SM et al. | [Genetic and biochemical control of biosynthesis of macrolide antibiotics]. | 1990 | Antibiot. Khimioter. | pmid:2078074 |
Fujiwara T and Takenaka S | Bioconversion of 19-deformyl-5-O-desosaminyl tylonolide to 19-deformyl-4'-deoxydesmycosin (TMC-016). | 1990 | FEMS Microbiol. Lett. | pmid:2379808 |
Roudaut B and Moretain JP | Residues of macrolide antibiotics in eggs following medication of laying hens. | 1990 | Br. Poult. Sci. | pmid:2245358 |
Morris FE et al. | Effect of rotating monensin plus tylosin and lasalocid on performance, ruminal fermentation, and site and extent of digestion in feedlot cattle. | 1990 | J. Anim. Sci. | pmid:2254185 |
MiliavskiÄ EB et al. | [Electrophoretic separation of spores of producers of kanamycin and tylosin]. | 1990 | Antibiot. Khimioter. | pmid:2334246 |
Fujiwara T et al. | Absorption, tissue distribution and excretion of 19-deformyldesmycosin derivatives, new 16-membered macrolides, in mice. | 1990 | J. Antibiot. | pmid:2324015 |
Panfilova ZI et al. | [Obtaining of mutants of Streptomyces fradiae producing tylosin by action of nitrosomethylurea on synchronously germinating spores]. | 1990 | Antibiot. Khimioter. | pmid:2383150 |
Collington GK et al. | The influence of inclusion of either an antibiotic or a probiotic in the diet on the development of digestive enzyme activity in the pig. | 1990 | Br. J. Nutr. | pmid:2119223 |
Huber ML et al. | Branched-chain fatty acids produced by mutants of Streptomyces fradiae, putative precursors of the lactone ring of tylosin. | 1990 | Antimicrob. Agents Chemother. | pmid:2221862 |
Coleman MR and Mowrey DH | Turbidimetric assay of tylosin in animal feeds containing urea. | 1990 Nov-Dec | J Assoc Off Anal Chem | pmid:2289924 |
Nakura H et al. | Formation of an antibacterial metabolite from a new macrolide compound 23-O-benzyl-5-mycaminosyl-tylonolide (TMC-101), by a hepatic microsomal drug-metabolizing enzyme system. | 1991 | J. Pharmacobio-dyn. | pmid:1802985 |
Rezanka T et al. | Isobutyrate as a precursor of n-butyrate in the biosynthesis of tylosine and fatty acids. | 1991 | FEMS Microbiol. Lett. | pmid:1769552 |
Rosteck PR et al. | Homology between proteins controlling Streptomyces fradiae tylosin resistance and ATP-binding transport. | 1991 | Gene | pmid:1864505 |
Lee SH and Lee KJ | Relationship between threonine dehydratase and biosynthesis of tylosin in Streptomyces fradiae. | 1991 | J. Gen. Microbiol. | pmid:1783901 |
Catchpole I and Dyke KG | Replication mutants of Staphylococcus aureus macrolide-lincosamide-streptogramin B resistance plasmid pT48. | 1991 | Mol. Microbiol. | pmid:1906970 |
Smith SC et al. | In-vitro antimicrobial susceptibility of Australian isolates of Treponema hyodysenteriae. | 1991 | Aust. Vet. J. | pmid:1839652 |
Schumann FJ et al. | Prophylactic medication of feedlot calves with tilmicosin. | 1991 | Vet. Rec. | pmid:2038809 |
Laven R and Andrews AH | Long-acting antibiotic formulations in the treatment of calf pneumonia: a comparative study of tilmicosin and oxytetracycline. | 1991 | Vet. Rec. | pmid:1926728 |