Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.
To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with Tylosin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
---|
Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).
Model | Cross reference | Weighted score | Related literatures |
---|
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
pmid: | ||||
Barth AD and Wood MR | The effect of streptomycin, oxytetracycline, tilmicosin and phenylbutazone on spermatogenesis in bulls. | 1998 | Can. Vet. J. | pmid:10051958 |
Aarestrup FM and Jensen NE | Susceptibility testing of Actinobacillus pleuropneumoniae in Denmark. Evaluation of three different media of MIC-determinations and tablet diffusion tests. | 1999 | Vet. Microbiol. | pmid:10063535 |
Jim GK et al. | A comparison of florfenicol and tilmicosin for the treatment of undifferentiated fever in feedlot calves in western Canada. | 1999 | Can. Vet. J. | pmid:10086218 |
Zweers-Zeilmaker WM et al. | In vitro complex formation and inhibition of hepatic cytochrome P450 activity by different macrolides and tiamulin in goats and cattle. | 1999 | Res. Vet. Sci. | pmid:10088712 |
Naranda A and Lopotar N | New derivatives of tylosin. IV. Dihydro and tetrahydro desmycosin oximes. | 1999 | J. Antibiot. | pmid:10092201 |
Karlsson M et al. | Genetic basis of macrolide and lincosamide resistance in Brachyspira (Serpulina) hyodysenteriae. | 1999 | FEMS Microbiol. Lett. | pmid:10188254 |
Owens WE et al. | Efficacy of parenterally or intramammarily administered tilmicosin or ceftiofur against Staphylococcus aureus mastitis during lactation. | 1999 | J. Dairy Sci. | pmid:10194686 |
Baltadzhieva D et al. | [Tylosin-specific proliferation in vitro of the peripheral blood mononuclear cells in occupational tylosin allergy]. | 1997 | Probl Khig | pmid:10202771 |
Pedersen KB | Some growth promoters in animals do confer antimicrobial resistance in humans. | 1999 | BMJ | pmid:10205122 |
Lee SH and Rho YT | Improvement of tylosin fermentation by mutation and medium optimization. | 1999 | Lett. Appl. Microbiol. | pmid:10206653 |
Scorneaux B and Shryock TR | The determination of the cellular volume of avian, porcine and bovine phagocytes and bovine mammary epithelial cells and its relationship to uptake of tilmicosin. | 1999 | J. Vet. Pharmacol. Ther. | pmid:10211711 |
Nickerson SC et al. | Comparison of tilmicosin and cephapirin as therapeutics for Staphylococcus aureus mastitis at dry-off. | 1999 | J. Dairy Sci. | pmid:10212455 |
Fouces R et al. | The tylosin biosynthetic cluster from Streptomyces fradiae: genetic organization of the left region. | 1999 | Microbiology (Reading, Engl.) | pmid:10220165 |
Robredo B et al. | From vanA Enterococcus hirae to vanA Enterococcus faecium: a study of feed supplementation with avoparcin and tylosin in young chickens. | 1999 | Antimicrob. Agents Chemother. | pmid:10223926 |
Huwyler U et al. | Efficacy evaluation of the use of oral tilmicosin in pneumonic calves. | 1999 | Schweiz. Arch. Tierheilkd. | pmid:10228400 |
Butler AR et al. | Impact of thioesterase activity on tylosin biosynthesis in Streptomyces fradiae. | 1999 | Chem. Biol. | pmid:10322123 |
Nagaraja TG et al. | Bacterial flora of liver abscesses in feedlot cattle fed tylosin or no tylosin. | 1999 | J. Anim. Sci. | pmid:10328365 |
Wilson VT and Cundliffe E | Molecular analysis of tlrB, an antibiotic-resistance gene from tylosin-producing Streptomyces fradiae, and discovery of a novel resistance mechanism. | 1999 | J. Antibiot. | pmid:10348045 |
Wallgren P et al. | Experimental infections with Actinobacillus pleuropneumoniae in pigs--II. Comparison of antibiotics for oral strategic treatment. | 1999 | Zentralblatt Veterinarmedizin Reihe B | pmid:10379236 |
Scorneaux B and Shryock TR | Intracellular accumulation, subcellular distribution, and efflux of tilmicosin in bovine mammary, blood, and lung cells. | 1999 | J. Dairy Sci. | pmid:10386306 |
Trefzer A et al. | Genes and enzymes involved in deoxysugar biosynthesis in bacteria. | 1999 | Nat Prod Rep | pmid:10399362 |
Modric S et al. | Effect of respiratory tract disease on pharmacokinetics of tilmicosin in rats. | 1999 | Lab. Anim. Sci. | pmid:10403438 |
Diarra MS et al. | Postantibiotic and physiological effects of tilmicosin, tylosin, and apramycin at subminimal and suprainhibitory concentrations on some swine and bovine respiratory tract pathogens. | 1999 | Int. J. Antimicrob. Agents | pmid:10461841 |
Bate N et al. | Multiple regulatory genes in the tylosin biosynthetic cluster of Streptomyces fradiae. | 1999 | Chem. Biol. | pmid:10467127 |
Crown LA and Smith RB | Accidental veterinary antibiotic injection into a farm worker. | 1999 | Tenn Med | pmid:10474305 |
Atef M et al. | Elimination of tilmicosin in lactating ewes. | 1999 | DTW. Dtsch. Tierarztl. Wochenschr. | pmid:10481373 |
Nagaraja TG et al. | Effects of tylosin on concentrations of Fusobacterium necrophorum and fermentation products in the rumen of cattle fed a high-concentrate diet. | 1999 | Am. J. Vet. Res. | pmid:10490072 |
Jordan FT et al. | The comparison of an aqueous preparation of tilmicosin with tylosin in the treatment of Mycoplasma gallisepticum infection of turkey poults. | 1999 Jul-Sep | Avian Dis. | pmid:10494422 |
Juhel-Gaugain M et al. | Multiresidue chromatographic method for the determination of macrolide residues in muscle by high-performance liquid chromatography with UV detection. | 1999 Sep-Oct | J AOAC Int | pmid:10513006 |
Tobback K et al. | Micellar electrokinetic capillary chromatography of macrolide antibiotics. Separation of tylosin, erythromycin and their related substances. | 1999 | J Chromatogr A | pmid:10536850 |
Short CR | Comparative pharmacokinetics--sorting the sheep from the goats. | 1999 | Vet. J. | pmid:10558834 |
Taha AA et al. | Disposition kinetics of tylosin administered intravenously and intramuscularly in desert sheep and Nubian goats. | 1999 | Vet. J. | pmid:10558841 |
Henderson JP and Ball HJ | Polyarthritis due to Mycoplasma bovis infection in adult dairy cattle in Northern Ireland. | 1999 | Vet. Rec. | pmid:10573196 |
Dudriková E et al. | Liquid chromatographic determination of tylosin in mastitic cow's milk following therapy. | 1999 Nov-Dec | J AOAC Int | pmid:10589481 |
Baltadzhieva D et al. | [Analysis of immunological indices of occupational sensibilization to tylosin]. | 1999 | Med Tr Prom Ekol | pmid:10605285 |
Bate N et al. | The mycarose-biosynthetic genes of Streptomyces fradiae, producer of tylosin. | 2000 | Microbiology (Reading, Engl.) | pmid:10658660 |
Davies R and Roberts TA | Antimicrobial susceptibility of enterococci recovered from commercial swine carcasses: effect of feed additives. | 1999 | Lett. Appl. Microbiol. | pmid:10664974 |
Vissiennon T et al. | Effect of avilamycin, tylosin and ionophore anticoccidials on Clostridium perfringens enterotoxaemia in chickens. | 2000 | Berl. Munch. Tierarztl. Wochenschr. | pmid:10684178 |
Mandić Z et al. | Tylosin derivatives. V. Electrochemical opening of oxirane ring. | 1999 | J. Antibiot. | pmid:10695679 |
Rabølle M and Spliid NH | Sorption and mobility of metronidazole, olaquindox, oxytetracycline and tylosin in soil. | 2000 | Chemosphere | pmid:10705549 |
Halling-Sørensen B | Algal toxicity of antibacterial agents used in intensive farming. | 2000 | Chemosphere | pmid:10705551 |
Baguer AJ et al. | Effects of the antibiotics oxytetracycline and tylosin on soil fauna. | 2000 | Chemosphere | pmid:10705553 |
Loke ML et al. | Stability of Tylosin A in manure containing test systems determined by high performance liquid chromatography. | 2000 | Chemosphere | pmid:10705554 |
Duff GC et al. | Effects of preshipping vs. arrival medication with tilmicosin phosphate and feeding chlortetracycline on health and performance of newly received beef cattle. | 2000 | J. Anim. Sci. | pmid:10709916 |
Fodor L et al. | Efficacy evaluations of the use of oral tilmicosin in pneumonic calves. | 2000 | Vet. J. | pmid:10712808 |
Visser IJ et al. | Failure of antibiotics gentamycin, tylosin, lincomycin and spectinomycin to eliminate Mycoplasma bovis in artificially infected frozen bovine semen. | 1999 | Theriogenology | pmid:10728994 |
Ayling RD et al. | Comparison of in vitro activity of danofloxacin, florfenicol, oxytetracycline, spectinomycin and tilmicosin against Mycoplasma mycoides subspecies mycoides small colony type. | 2000 | Vet. Rec. | pmid:10737293 |
Montesissa C et al. | Tylosin depletion in edible tissues of turkeys. | 1999 | Food Addit Contam | pmid:10755131 |
Croft A et al. | The effect of tilmicosin administered to ewes prior to lambing on incidence of clinical mastitis and subsequent lamb performance. | 2000 | Can. Vet. J. | pmid:10769768 |