Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.
To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Tylosin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Moore GM et al. | Efficacy dose determination study of tilmicosin phosphate in feed for control of pneumonia caused by Actinobacillus pleuropneumoniae in swine. | 1996 | Am. J. Vet. Res. | pmid:8633812 |
Moore GM et al. | Clinical field trials with tilmicosin phosphate in feed for the control of naturally acquired pneumonia caused by Actinobacillus pleuropneumoniae and Pasteurella multocida in swine. | 1996 | Am. J. Vet. Res. | pmid:8633813 |
Shen J et al. | Pharmacokinetics of tilmicosin after oral administration in swine. | 2005 | Am. J. Vet. Res. | pmid:16008233 |
Mendoza J et al. | Concentrations of tilmicosin in mammary gland secretions of dairy cows following subcutaneous administration of one or two doses of an experimental preparation of tilmicosin and its efficacy against intramammary infections caused by Staphylococcus aureus. | 2016 | Am. J. Vet. Res. | pmid:27580103 |
Fajt VR et al. | Effect of danofloxacin and tilmicosin on body temperatures of beef calves with pneumonia experimentally induced by inoculation with Mannheimia haemolytica. | 2004 | Am. J. Vet. Res. | pmid:15141881 |
Confer AW et al. | Clinical disease and lung lesions in calves experimentally inoculated with Histophilus somni five days after metaphylactic administration of tildipirosin or tulathromycin. | 2016 | Am. J. Vet. Res. | pmid:27027834 |
Blondeau JM et al. | Bactericidal effects of various concentrations of enrofloxacin, florfenicol, tilmicosin phosphate, and tulathromycin on clinical isolates of Mannheimia haemolytica. | 2015 | Am. J. Vet. Res. | pmid:26413823 |
McOrist S et al. | Oral administration of tylosin phosphate for treatment and prevention of proliferative enteropathy in pigs. | 1997 | Am. J. Vet. Res. | pmid:9028475 |
Kim HB et al. | Effects of tylosin administration on C-reactive protein concentration and carriage of Salmonella enterica in pigs. | 2014 | Am. J. Vet. Res. | pmid:24762018 |
Jacks TM et al. | 3-Acetyl-4''-isovaleryl tylosin for prevention of swine dysentery. | 1986 | Am. J. Vet. Res. | pmid:3789492 |