Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.
To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Tylosin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Lee SH and Rho YT | Improvement of tylosin fermentation by mutation and medium optimization. | 1999 | Lett. Appl. Microbiol. | pmid:10206653 |
Pedersen KB | Some growth promoters in animals do confer antimicrobial resistance in humans. | 1999 | BMJ | pmid:10205122 |
Baltadzhieva D et al. | [Tylosin-specific proliferation in vitro of the peripheral blood mononuclear cells in occupational tylosin allergy]. | 1997 | Probl Khig | pmid:10202771 |
Owens WE et al. | Efficacy of parenterally or intramammarily administered tilmicosin or ceftiofur against Staphylococcus aureus mastitis during lactation. | 1999 | J. Dairy Sci. | pmid:10194686 |
Karlsson M et al. | Genetic basis of macrolide and lincosamide resistance in Brachyspira (Serpulina) hyodysenteriae. | 1999 | FEMS Microbiol. Lett. | pmid:10188254 |
Naranda A and Lopotar N | New derivatives of tylosin. IV. Dihydro and tetrahydro desmycosin oximes. | 1999 | J. Antibiot. | pmid:10092201 |
Zweers-Zeilmaker WM et al. | In vitro complex formation and inhibition of hepatic cytochrome P450 activity by different macrolides and tiamulin in goats and cattle. | 1999 | Res. Vet. Sci. | pmid:10088712 |
Jim GK et al. | A comparison of florfenicol and tilmicosin for the treatment of undifferentiated fever in feedlot calves in western Canada. | 1999 | Can. Vet. J. | pmid:10086218 |
Aarestrup FM and Jensen NE | Susceptibility testing of Actinobacillus pleuropneumoniae in Denmark. Evaluation of three different media of MIC-determinations and tablet diffusion tests. | 1999 | Vet. Microbiol. | pmid:10063535 |
Barth AD and Wood MR | The effect of streptomycin, oxytetracycline, tilmicosin and phenylbutazone on spermatogenesis in bulls. | 1998 | Can. Vet. J. | pmid:10051958 |
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