Tylosin

Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Tylosin?

Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Tylosin

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Diarrhea D003967 32 associated lipids
Bacterial Infections D001424 21 associated lipids
Colitis D003092 69 associated lipids
Cattle Diseases D002418 24 associated lipids
Body Weight D001835 333 associated lipids
Facial Dermatoses D005148 7 associated lipids
Occupational Diseases D009784 42 associated lipids
Asthma D001249 52 associated lipids
Weight Gain D015430 101 associated lipids
Foreign Bodies D005547 5 associated lipids
Hyperplasia D006965 34 associated lipids
Clostridium Infections D003015 5 associated lipids
Ataxia D001259 20 associated lipids
Staphylococcal Skin Infections D013207 9 associated lipids
Bacteriuria D001437 7 associated lipids
Pasteurella Infections D010326 8 associated lipids
Swine Diseases D013553 16 associated lipids
Poultry Diseases D011201 21 associated lipids
Vasculitis D014657 14 associated lipids
Pyoderma D011711 5 associated lipids
Lymphadenitis D008199 8 associated lipids
Campylobacter Infections D002169 13 associated lipids
Mycoplasma Infections D009175 13 associated lipids
Pasteurellosis, Pneumonic D012766 3 associated lipids
Pneumonia, Bacterial D018410 16 associated lipids
Liver Abscess D008100 6 associated lipids
Treponemal Infections D014211 3 associated lipids
Dysentery D004403 4 associated lipids
Mycoplasmatales Infections D009180 6 associated lipids
Mycotoxicosis D015651 5 associated lipids
Porcine Reproductive and Respiratory Syndrome D019318 4 associated lipids
Ureaplasma Infections D016869 5 associated lipids
Pneumonia, Mycoplasma D011019 6 associated lipids
Tracheal Diseases D014133 3 associated lipids
Bacillaceae Infections D016863 1 associated lipids
Erysipelothrix Infections D004889 1 associated lipids
Keratoconjunctivitis, Infectious D007639 2 associated lipids
Neisseriaceae Infections D016870 3 associated lipids
Conjunctivitis, Viral D003236 1 associated lipids
Enterotoxemia D004767 1 associated lipids
Bovine Respiratory Disease Complex D048090 2 associated lipids
Desulfovibrionaceae Infections D045824 5 associated lipids
Primate Diseases D018419 2 associated lipids
Pneumonia of Calves, Enzootic D048089 2 associated lipids
Pneumonia of Swine, Mycoplasmal D045729 2 associated lipids
Digital Dermatitis D058066 3 associated lipids
Per page 10 20 50 | Total 47

PubChem Associated disorders and diseases

What pathways are associated with Tylosin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Tylosin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Tylosin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Tylosin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Tylosin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Tylosin?

Knock-out

Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

NCBI Entrez Crosslinks

All references with Tylosin

Download all related citations
Per page 10 20 50 100 | Total 931
Authors Title Published Journal PubMed Link
Cummings TS et al. Effect of medicated feed on tracheal infection and population of Mycoplasma gallisepticum in chickens. 1986 Jul-Sep Avian Dis. pmid:3767816
Stipkovits L et al. In vitro testing of the anti-mycoplasma effect of some anti-coccidial drugs. 1987 Vet. Microbiol. pmid:3439016
Blaha T et al. Swine dysentery control in the German Democratic Republic and the suitability of injections of tiamulin for the programme. 1987 Vet. Rec. pmid:3424604
Rodionova II et al. [Effect of protoplast formation on the antibiotic activity of the Streptomyces fradiae 165 strain--a producer of tylosin]. 1987 Antibiot. Med. Biotekhnol. pmid:2830838
Kaukas A et al. The effect of ampicillin and tylosin on the faecal enterococci of healthy young chickens. 1987 J. Appl. Bacteriol. pmid:3112089
Nagaraja TG and Taylor MB Susceptibility and resistance of ruminal bacteria to antimicrobial feed additives. 1987 Appl. Environ. Microbiol. pmid:3116929
Fishman SE et al. Cloning genes for the biosynthesis of a macrolide antibiotic. 1987 Proc. Natl. Acad. Sci. U.S.A. pmid:3479787
Ose EE In vitro antibacterial properties of EL-870, a new semi-synthetic macrolide antibiotic. 1987 J. Antibiot. pmid:3570967
Wiley PF et al. Enzymatic phosphorylation of macrolide antibiotics. 1987 J. Antibiot. pmid:3570968
Kiyoshima K et al. New tylosin analogs produced by mutants of Streptomyces fradiae. 1987 J. Antibiot. pmid:3680024
Takeuchi T et al. 4''-O-(4-methoxyphenyl)-acetyltylosin, a new macrolide derivative of therapeutic importance. 1987 J. Antibiot. pmid:3680047
Greer RT and Ryoo JP Development of ocular inserts for cattle. 1987 Scanning Microsc. pmid:3616580
Ball HJ and McCaughey WJ Experimental intramuscular inoculation of tylosin in the elimination of ureaplasmas from ewes. 1987 Vet. Rec. pmid:3617407
Westerbeek JA and Jaartsveld FH [Mycoplasma infection on a cattle farm]. 1987 Tijdschr Diergeneeskd pmid:3603536
Vancura A et al. Fatty acids and production of tylosin-like compounds in Streptomyces fradiae. 1987 J. Basic Microbiol. pmid:3625475
Bauer NJ et al. Purification, characterization, and kinetic mechanism of S-adenosyl-L-methionine:macrocin O-methyltransferase from Streptomyces fradiae. 1988 J. Biol. Chem. pmid:3170601
Kreuzman AJ et al. Two distinctive O-methyltransferases catalyzing penultimate and terminal reactions of macrolide antibiotic (tylosin) biosynthesis. Substrate specificity, enzyme inhibition, and kinetic mechanism. 1988 J. Biol. Chem. pmid:3170602
Kirst HA et al. Synthesis and evaluation of tylosin-related macrolides modified at the aldehyde function: a new series of orally effective antibiotics. 1988 J. Med. Chem. pmid:3398001
Kirst HA et al. In vitro and in vivo evaluation of C-20- and C-23-modified derivatives of tylosin against veterinary pathogens. 1988 J. Antibiot. pmid:3417566
Ose EE and Tonkinson LV Single-dose treatment of neonatal calf pneumonia with the new macrolide antibiotic tilmicosin. 1988 Vet. Rec. pmid:3195026