Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.
To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Tylosin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Wardlaw AC et al. | Bactericidal activity in the pig roundworm Ascaris suum. | 1994 | J. Appl. Bacteriol. | pmid:8144403 |
Inouye M et al. | Cloning and sequences of two macrolide-resistance-encoding genes from mycinamicin-producing Micromonospora griseorubida. | 1994 | Gene | pmid:8163173 |
Scott PR | Field study of undifferentiated respiratory disease in housed beef calves. | 1994 | Vet. Rec. | pmid:8203107 |
Coronato S et al. | A simple method to eliminate mycoplasma from cell cultures. | 1994 | J. Virol. Methods | pmid:8175949 |
Tang L et al. | Amino acid catabolism and antibiotic synthesis: valine is a source of precursors for macrolide biosynthesis in Streptomyces ambofaciens and Streptomyces fradiae. | 1994 | J. Bacteriol. | pmid:7928973 |
Merson-Davies LA and Cundliffe E | Analysis of five tylosin biosynthetic genes from the tyllBA region of the Streptomyces fradiae genome. | 1994 | Mol. Microbiol. | pmid:7984112 |
Inamoto T et al. | Antibacterial activity of tilmicosin against Pasteurella multocida and Actinobacillus pleuropneumoniae isolated from pneumonic lesions in swine. | 1994 | J. Vet. Med. Sci. | pmid:7865594 |
Caraffini S et al. | Tylosin, an airborne contact allergen in veterinarians. | 1994 | Contact Derm. | pmid:7867337 |
Lee SH and Lee KJ | Kinetics of the repression of tylosin biosynthesis by ammonium ion in Streptomyces fradiae. | 1994 | J. Biotechnol. | pmid:7764561 |
Danese P et al. | Occupational contact dermatitis from tylosin. | 1994 | Contact Derm. | pmid:8187499 |
Tan ZL et al. | Serum neutralizing antibodies against Fusobacterium necrophorum leukotoxin in cattle with experimentally induced or naturally developed hepatic abscesses. | 1994 | J. Anim. Sci. | pmid:8157537 |
Buller NB and Hampson DJ | Antimicrobial susceptibility testing of Serpulina hyodysenteriae. | 1994 | Aust. Vet. J. | pmid:7945100 |
Shryock TR et al. | Effect of bentonite incorporated in a feed ration with tilmicosin in the prevention of induced Mycoplasma gallisepticum airsacculitis in broiler chickens. | 1994 Jul-Sep | Avian Dis. | pmid:7832702 |
Chan W et al. | Determination of tylosin and tilmicosin residues in animal tissues by reversed-phase liquid chromatography. | 1994 Mar-Apr | J AOAC Int | pmid:8199468 |
Nguyen LT et al. | The tylosin producer, Streptomyces fradiae, contains a second valine dehydrogenase. | 1995 | Microbiology (Reading, Engl.) | pmid:7773408 |
Paesen J et al. | Isolation of decomposition products of tylosin using liquid chromatography. | 1995 | J Chromatogr A | pmid:7757214 |
Shryock TR et al. | Proposed quality control guidelines for antimicrobial susceptibility tests using tilmicosin. | 1995 | J. Clin. Microbiol. | pmid:7714188 |
Bobillot S et al. | Chemical modification of tylosin. | 1995 | J. Antibiot. | pmid:7649866 |
Creemer LC et al. | Synthesis, antimicrobial activity and in vivo fluorine NMR of a hexafluorinated derivative of tilmicosin. | 1995 | J. Antibiot. | pmid:7649867 |
Narandja A et al. | 10,11,12,13-Tetrahydro derivatives of tylosin. II. Synthesis, antibacterial activity and tissue of 4'-deoxy-10,11,12,13-tetrahydrodesmycosin. | 1995 | J. Antibiot. | pmid:7730160 |
Paesen J et al. | Study of the stability of tylosin A in aqueous solutions. | 1995 | J Pharm Biomed Anal | pmid:8573642 |
Ziv G et al. | Disposition kinetics of tylosin tartrate administered intravenously and intramuscularly to normal and water-deprived camels. | 1995 | J. Vet. Pharmacol. Ther. | pmid:8583543 |
Ziv G et al. | Tilmicosin antibacterial activity and pharmacokinetics in cows. | 1995 | J. Vet. Pharmacol. Ther. | pmid:8587151 |
Brown SA et al. | Characterization of plasma and lung concentrations after ceftiofur sodium and tilmicosin phosphate administered subcutaneously to mice. | 1995 | J. Vet. Pharmacol. Ther. | pmid:8587160 |
Blackall PJ et al. | In-vitro antibacterial properties of tilmicosin against Australian isolates of Pasteurella multocida and Actinobacillus pleuropneumoniae from pigs. | 1995 | Aust. Vet. J. | pmid:8787526 |
Tuomi ML and Räsänen L | Contact allergy to tylosin and cobalt in a pig-farmer. | 1995 | Contact Derm. | pmid:8654098 |
Lee SH and Lee KJ | Threonine dehydratases in different strains of Streptomyces fradiae. | 1995 | J. Biotechnol. | pmid:8562022 |
Kirchgessner M et al. | [Effect of avilamycin and tylosin on the metabolizable energy in growing and finishing pigs]. | 1995 | Arch Tierernahr | pmid:8526732 |
Kiehl DE and Kennington AS | Analysis of tilmicosin in swine liver extracts by liquid chromatography/atmospheric pressure chemical ionization mass spectrometry. | 1995 | Rapid Commun. Mass Spectrom. | pmid:8527821 |
Harvey RB et al. | Influence of the antibiotics lincomycin and tylosin on aflatoxicosis when added to aflatoxin-contaminated diets of growing swine. | 1995 | J. Vet. Diagn. Invest. | pmid:7578454 |
Stock RA et al. | Effect of monensin and monensin and tylosin combination on feed intake variation of feedlot steers. | 1995 | J. Anim. Sci. | pmid:7601752 |
Zuzulova M et al. | In vitro activity of tylosin and its derivatives against Ureaplasma urealyticum. | 1995 | Arzneimittelforschung | pmid:8929244 |
Galyean ML et al. | Effects of arrival medication with tilmicosin phosphate on health and performance of newly received beef cattle. | 1995 | J. Anim. Sci. | pmid:7665351 |
Scott PR | Efficacy of strategic tilmicosin injection during an outbreak of respiratory disease in housed beef calves. | 1995 Sep-Oct | Br. Vet. J. | pmid:8556318 |
Moore GM et al. | Efficacy dose determination study of tilmicosin phosphate in feed for control of pneumonia caused by Actinobacillus pleuropneumoniae in swine. | 1996 | Am. J. Vet. Res. | pmid:8633812 |
Moore GM et al. | Clinical field trials with tilmicosin phosphate in feed for the control of naturally acquired pneumonia caused by Actinobacillus pleuropneumoniae and Pasteurella multocida in swine. | 1996 | Am. J. Vet. Res. | pmid:8633813 |
Day FG | The value of tilmicosin in production medicine. | 1996 | J. Am. Vet. Med. Assoc. | pmid:8617615 |
Solenberg PJ et al. | Transposition mutagenesis in Streptomyces fradiae: identification of a neutral site for the stable insertion of DNA by transposon exchange. | 1996 | Gene | pmid:8626067 |
Arisawa A et al. | Direct fermentative production of acyltylosins by genetically-engineered strains of Streptomyces fradiae. | 1996 | J. Antibiot. | pmid:8641997 |
Main BW et al. | Cardiovascular effects of the macrolide antibiotic tilmicosin, administered alone and in combination with propranolol or dobutamine, in conscious unrestrained dogs. | 1996 | J. Vet. Pharmacol. Ther. | pmid:8803881 |
Katoh T et al. | The fractional inhibitory concentration index of antimicrobial agents for bacteria and Mycoplasma isolated from the nasal swabs of cattle with respiratory diseases. | 1996 | J. Vet. Med. Sci. | pmid:8877979 |
Katoh T et al. | Effect of a combination of antimicrobial agents for the treatment of respiratory disease in cattle. | 1996 | J. Vet. Med. Sci. | pmid:8877980 |
McKay SG et al. | Use of tilmicosin for treatment of pasteurellosis in rabbits. | 1996 | Am. J. Vet. Res. | pmid:8836371 |
Shryock TR et al. | Minimum inhibitory concentration breakpoints and disk diffusion inhibitory zone interpretive criteria for tilmicosin susceptibility testing against Pasteurella spp. associated with bovine respiratory disease. | 1996 | J. Vet. Diagn. Invest. | pmid:8844577 |
Scott DW et al. | Further studies on the efficacy of tylosin tablets for the treatment of pyoderma due to Staphylococcus intermedius infection in dogs. | 1996 | Can. Vet. J. | pmid:8896878 |
Harvey RG | Tylosin in the treatment of canine superficial pyoderma. | 1996 | Vet. Rec. | pmid:8873399 |
Kobayashi H et al. | Macrolide susceptibility of Mycoplasma hyorhinis isolated from piglets. | 1996 | Antimicrob. Agents Chemother. | pmid:8849222 |
Kobayashi H et al. | In vitro susceptibility of Mycoplasma hyosynoviae and M. hyorhinis to antimicrobial agents. | 1996 | J. Vet. Med. Sci. | pmid:8959659 |
Molnár L | Sensitivity of strains of Serpulina hyodysenteriae isolated in Hungary to chemotherapeutic drugs. | 1996 | Vet. Rec. | pmid:8677605 |
Kuhstoss S et al. | Production of a novel polyketide through the construction of a hybrid polyketide synthase. | 1996 | Gene | pmid:8996112 |