Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.
To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Tylosin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Ramlachan N et al. | A comparative study on the effects of tylosin on select bacteria during continuous flow culture of mixed populations of gut microflora derived from a feral and a domestic pig. | 2008 | Foodborne Pathog. Dis. | pmid:18260812 |
Jacob ME et al. | Effects of feeding wet corn distillers grains with solubles with or without monensin and tylosin on the prevalence and antimicrobial susceptibilities of fecal foodborne pathogenic and commensal bacteria in feedlot cattle. | 2008 | J. Anim. Sci. | pmid:18192558 |
Achard A et al. | Emergence of macrolide resistance gene mph(B) in Streptococcus uberis and cooperative effects with rdmC-like gene. | 2008 | Antimicrob. Agents Chemother. | pmid:18519724 |
Shimada T et al. | Inhibitory effects of the macrolide antimicrobial tylosin on anaerobic treatment. | 2008 | Biotechnol. Bioeng. | pmid:18646223 |
Caldwell DB et al. | Development, stability, and molecular mechanisms of macrolide resistance in Campylobacter jejuni. | 2008 | Antimicrob. Agents Chemother. | pmid:18779354 |
Giadinis ND et al. | Mortality in adult goats attributed to Mycoplasma capricolum subspecies capricolum. | 2008 | Vet. Rec. | pmid:18757908 |
Parker KI et al. | Quarter-level analysis of subclinical and clinical mastitis in primiparous heifers following the use of a teat sealant or an injectable antibiotic, or both, precalving. | 2008 | J. Dairy Sci. | pmid:18096938 |
Crespo R and McMillan R | Facial cellulitis induced in chickens by Mycoplasma gallisepticum bacterin and its treatment. | 2008 | Avian Dis. | pmid:19166067 |
Van Donkersgoed J et al. | Comparative efficacy of tilmicosin versus tulathromycin as a metaphylactic antimicrobial in feedlot calves at moderate risk for respiratory disease. | 2008 | Vet. Ther. | pmid:19177334 |
Lilia G et al. | Circadian serum concentrations of tylosin in broilers after feed or water medication. | 2008 | Br. Poult. Sci. | pmid:18836909 |
Cundliffe E | Control of tylosin biosynthesis in Streptomyces fradiae. | 2008 | J. Microbiol. Biotechnol. | pmid:18852501 |
Fricke JA et al. | Pharmacokinetics and tissue depletion of tilmicosin in turkeys. | 2008 | J. Vet. Pharmacol. Ther. | pmid:19000285 |
Beltran-Alcrudo D et al. | A persistent outbreak of ulcerative enteritis in bobwhite quail (Colinus virginianus). | 2008 | Avian Dis. | pmid:18939648 |
Weber TE and Kerr BJ | Effect of sodium butyrate on growth performance and response to lipopolysaccharide in weanling pigs. | 2008 | J. Anim. Sci. | pmid:17998428 |
Pol-Hofstad I et al. | Collaborative study of a microbiological screening method (three-plate) for the banned antimicrobial growth promotors tylosin, virginiamycin, spiramycin, zinc bacitracin and avoparcin in animal feed. | 2008 | Food Addit Contam Part A Chem Anal Control Expo Risk Assess | pmid:19680856 |
Blackwood RS et al. | Effects of the macrolide drug tylosin on chronic diarrhea in rhesus macaques (Macaca mulatta). | 2008 | Comp. Med. | pmid:19793461 |
Demoling LA and Bååth E | No long-term persistence of bacterial pollution-induced community tolerance in tylosin-polluted soil. | 2008 | Environ. Sci. Technol. | pmid:18853809 |
Castonguay R et al. | Stereospecificity of ketoreductase domains 1 and 2 of the tylactone modular polyketide synthase. | 2008 | J. Am. Chem. Soc. | pmid:18693734 |
Petropoulos AD et al. | Stepwise binding of tylosin and erythromycin to Escherichia coli ribosomes, characterized by kinetic and footprinting analysis. | 2008 | J. Biol. Chem. | pmid:18079110 |
Akhter S et al. | Effect of antibiotics in extender on bacterial and spermatozoal quality of cooled buffalo (Bubalus bubalis) bull semen. | 2008 | Reprod. Domest. Anim. | pmid:18042206 |
Bailey M et al. | Induction of erm(C) expression by noninducing antibiotics. | 2008 | Antimicrob. Agents Chemother. | pmid:18086834 |
Diagnosis | pasteurellosis. | 2008 | Lab Anim (NY) | pmid:18094697 | |
Wagner BA et al. | Effect of antimicrobial dosage regimen on Salmonella and Escherichia coli isolates from feeder swine. | 2008 | Appl. Environ. Microbiol. | pmid:18223115 |
Kim MH et al. | Comparative pharmacokinetics of tylosin or florfenicol after a single intramuscular administration at two different doses of tylosin-florfenicol combination in pigs. | 2008 | J. Vet. Med. Sci. | pmid:18250580 |
Angenent LT et al. | Effect of the presence of the antimicrobial tylosin in swine waste on anaerobic treatment. | 2008 | Water Res. | pmid:18258277 |
Korshunova GA et al. | [Peptide derivatives of tylosin-related macrolides]. | 2007 Mar-Apr | Bioorg. Khim. | pmid:17476984 |
Sassman SA et al. | Sorption of tylosin A, D, and A-aldol and degradation of tylosin A in soils. | 2007 | Environ. Toxicol. Chem. | pmid:17702335 |
Ladely SR et al. | Development of macrolide-resistant Campylobacter in broilers administered subtherapeutic or therapeutic concentrations of tylosin. | 2007 | J. Food Prot. | pmid:17803155 |
MartÃnez MF and Barth AD | Early detection and treatment of vesicular adenitis in bulls. | 2007 | Anim. Reprod. Sci. | pmid:17027202 |
Lüthje P and Schwarz S | Molecular analysis of constitutively expressed erm(C) genes selected in vitro in the presence of the non-inducers pirlimycin, spiramycin and tylosin. | 2007 | J. Antimicrob. Chemother. | pmid:17085767 |
Szczepanowski R et al. | Novel macrolide resistance module carried by the IncP-1beta resistance plasmid pRSB111, isolated from a wastewater treatment plant. | 2007 | Antimicrob. Agents Chemother. | pmid:17101677 |
Booker CW et al. | Evaluation of the efficacy of tulathromycin as a metaphylactic antimicrobial in feedlot calves. | 2007 | Vet. Ther. | pmid:17926304 |
Boissevain I | [Punishment after the fact]. | 2007 | Tijdschr Diergeneeskd | pmid:17939495 |
González de la Huebra MJ et al. | Sample preparation strategy for the simultaneous determination of macrolide antibiotics in animal feedingstuffs by liquid chromatography with electrochemical detection (HPLC-ECD). | 2007 | J Pharm Biomed Anal | pmid:17257795 |
Kart A et al. | The possible protective effect of L-carnitine on tilmicosin-induced cardiotoxicity in mice. | 2007 | J Vet Med A Physiol Pathol Clin Med | pmid:17381679 |
Lin J et al. | Effect of macrolide usage on emergence of erythromycin-resistant Campylobacter isolates in chickens. | 2007 | Antimicrob. Agents Chemother. | pmid:17353243 |
Litterio NJ et al. | Microbiological screening test validation for detection of tylosin excretion in milk of cows with low and high somatic cell counts. | 2007 | J Vet Med A Physiol Pathol Clin Med | pmid:17359452 |
Thompson TS et al. | Degradation of incurred tylosin to desmycosin--implications for residue analysis of honey. | 2007 | Anal. Chim. Acta | pmid:17386728 |
Hu D and Coats JR | Aerobic degradation and photolysis of tylosin in water and soil. | 2007 | Environ. Toxicol. Chem. | pmid:17521133 |
Song W et al. | Determination of amprolium, carbadox, monensin, and tylosin in surface water by liquid chromatography/tandem mass spectrometry. | 2007 | Rapid Commun. Mass Spectrom. | pmid:17510929 |
Vincent U et al. | Validation of an analytical method for the determination of spiramycin, virginiamycin and tylosin in feeding-stuffs by thin-layer chromatography and bio-autography. | 2007 | Food Addit Contam | pmid:17454108 |
Berrang ME et al. | Subtherapeutic tylosin phosphate in broiler feed affects Campylobacter on carcasses during processing. | 2007 | Poult. Sci. | pmid:17495097 |
Herrera M et al. | Quantitative determination of tilmicosin in canine serum by high performance liquid chromatography-tandem mass spectrometry. | 2007 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:17627909 |
Xie W et al. | [Determination of five macrolide antibiotic residues in royal jelly samples by using high performance liquid chromatography tandem mass spectrometry]. | 2007 | Se Pu | pmid:17679440 |
Werner JJ et al. | Environmental photochemistry of tylosin: efficient, reversible photoisomerization to a less-active isomer, followed by photolysis. | 2007 | J. Agric. Food Chem. | pmid:17655244 |
Antunes NT et al. | In vitro susceptibilities of Mycoplasma putrefaciens field isolates. | 2007 | Antimicrob. Agents Chemother. | pmid:17638695 |
Nagaraja TG and Lechtenberg KF | Liver abscesses in feedlot cattle. | 2007 | Vet. Clin. North Am. Food Anim. Pract. | pmid:17606156 |
Murphy MW et al. | Airborne antibiotic concentrations in a swine feeding operation. | 2007 | J Agric Saf Health | pmid:18075012 |
Choi D et al. | Tylosin production by Streptomyces fradiae using raw cornmeal in airlift bioreactor. | 2007 | J. Microbiol. Biotechnol. | pmid:18051315 |
Nouri M and Constable PD | Effect of parenteral administration of erythromycin, tilmicosin, and tylosin on abomasal emptying rate in suckling calves. | 2007 | Am. J. Vet. Res. | pmid:18052746 |