Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.
To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Tylosin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Scott DW et al. | Further studies on the efficacy of tylosin tablets for the treatment of pyoderma due to Staphylococcus intermedius infection in dogs. | 1996 | Can. Vet. J. | pmid:8896878 |
Houglum JE and Tasler MK | Liquid chromatographic assay of tylosin in animal feeds. | 1996 Mar-Apr | J AOAC Int | pmid:8920123 |
Delépine B et al. | Multiresidue method for confirmation of macrolide antibiotics in bovine muscle by liquid chromatography/mass spectrometry. | 1996 Mar-Apr | J AOAC Int | pmid:8920126 |
Zuzulova M et al. | In vitro activity of tylosin and its derivatives against Ureaplasma urealyticum. | 1995 | Arzneimittelforschung | pmid:8929244 |
Markakis PK | Microbiological method for determining macrolides in animal feeds in the presence of other drugs by thin-layer chromatography detection. | 1996 Nov-Dec | J AOAC Int | pmid:8946704 |
Kobayashi H et al. | In vitro susceptibility of Mycoplasma hyosynoviae and M. hyorhinis to antimicrobial agents. | 1996 | J. Vet. Med. Sci. | pmid:8959659 |
Fish SA and Cundliffe E | Structure-activity studies of tylosin-related macrolides. | 1996 | J. Antibiot. | pmid:8968399 |
Gandecha AR and Cundliffe E | Molecular analysis of tlrD, an MLS resistance determinant from the tylosin producer, Streptomyces fradiae. | 1996 | Gene | pmid:8973363 |
Kuhstoss S et al. | Production of a novel polyketide through the construction of a hybrid polyketide synthase. | 1996 | Gene | pmid:8996112 |
McOrist S et al. | Oral administration of tylosin phosphate for treatment and prevention of proliferative enteropathy in pigs. | 1997 | Am. J. Vet. Res. | pmid:9028475 |