Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.
To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Tylosin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Aarestrup FM and Carstensen B | Effect of tylosin used as a growth promoter on the occurrence of macrolide-resistant enterococci and staphylococci in pigs. | 1998 | Microb. Drug Resist. | pmid:9988049 |
Modric S et al. | Pharmacokinetics and pharmacodynamics of tilmicosin in sheep and cattle. | 1998 | J. Vet. Pharmacol. Ther. | pmid:9885967 |
Jordan FT et al. | In vitro and in vivo comparisons of valnemulin, tiamulin, tylosin, enrofloxacin, and lincomycin/spectinomycin against Mycoplasma gallisepticum. | 1998 Oct-Dec | Avian Dis. | pmid:9876842 |
Koenen-Dierick K and De Beer JO | Optimization of an antibiotic residue screening test, based on inhibition of Bacillus subtilis BGA, with experimental design. | 1998 | Food Addit Contam | pmid:9829036 |
Oh TG et al. | Induction of ermAMR from a clinical strain of Enterococcus faecalis by 16-membered-ring macrolide antibiotics. | 1998 | J. Bacteriol. | pmid:9791136 |
Scorneaux B and Shryock TR | Intracellular accumulation, subcellular distribution, and efflux of tilmicosin in chicken phagocytes. | 1998 | Poult. Sci. | pmid:9776059 |
Berque I et al. | [Stereoselective synthesis of biologically active macrolides. Total synthesis of tylosine]. | 1998 | Ann Pharm Fr | pmid:9770007 |
De Liguoro M et al. | Determination of tylosin residues in pig tissues using high-performance liquid chromatography. | 1998 | Analyst | pmid:9764508 |
Baba T et al. | Effect of tylosin tartrate (Tylan Soluble) on cellular immune responses in chickens. | 1998 | Poult. Sci. | pmid:9733118 |
Grdisa M et al. | Effect of a 17-member azalide on tumor cell growth. | 1998 Sep-Oct | Chemotherapy | pmid:9732149 |
Scorneaux B and Shryock TR | Intracellular accumulation, subcellular distribution and efflux of tilmicosin in swine phagocytes. | 1998 | J. Vet. Pharmacol. Ther. | pmid:9731947 |
Gotoh Y et al. | Chemical transformation of tylosin derivatives into neutral macrolides having a 3'-methoxyl group. | 1998 | Carbohydr. Res. | pmid:9720235 |
Beharka AA and Nagaraja TG | Effect of Aspergillus oryzae extract alone or in combination with antimicrobial compounds on ruminal bacteria. | 1998 | J. Dairy Sci. | pmid:9684165 |
Baba T et al. | Effect of tylosin tartrate on humoral immune responses in chickens. | 1998 | Zentralblatt Veterinarmedizin Reihe B | pmid:9673579 |
Wilson VT and Cundliffe E | Characterization and targeted disruption of a glycosyltransferase gene in the tylosin producer, Streptomyces fradiae. | 1998 | Gene | pmid:9651492 |
Choi DB et al. | Effects of rapessed oil on activity of methylmalonyl-CoA carboxyltransferase in culture of Streptomyces fradiae. | 1998 | Biosci. Biotechnol. Biochem. | pmid:9648221 |
Shryock TR et al. | Antimicrobial susceptibility of Moraxella bovis. | 1998 | Vet. Microbiol. | pmid:9646479 |
Aarestrup FM and Friis NF | Antimicrobial susceptibility testing of Mycoplasma hyosynoviae isolated from pigs during 1968 to 1971 and during 1995 and 1996. | 1998 | Vet. Microbiol. | pmid:9646463 |
Vogel GJ et al. | Effects of tilmicosin on acute undifferentiated respiratory tract disease in newly arrived feedlot cattle. | 1998 | J. Am. Vet. Med. Assoc. | pmid:9638194 |
Esipov SE | [Novel mathematical approach to determination of antibiotics concentration by agar diffusion method. Analysis of graphical, table and mathematical options of relative biological activity estimation]. | 1998 | Antibiot. Khimioter. | pmid:9606490 |