Tylosin

Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Tylosin?

Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Tylosin

MeSH term MeSH ID Detail
Diarrhea D003967 32 associated lipids
Dysentery D004403 4 associated lipids
Enterotoxemia D004767 1 associated lipids
Erysipelothrix Infections D004889 1 associated lipids
Facial Dermatoses D005148 7 associated lipids
Foreign Bodies D005547 5 associated lipids
Hemolysis D006461 131 associated lipids
Hyperplasia D006965 34 associated lipids
Keratoconjunctivitis, Infectious D007639 2 associated lipids
Liver Abscess D008100 6 associated lipids
Per page 10 20 50 | Total 47

PubChem Associated disorders and diseases

What pathways are associated with Tylosin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Tylosin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Tylosin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Tylosin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Tylosin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Tylosin?

Knock-out

Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Tylosin

Download all related citations
Per page 10 20 50 100 | Total 931
Authors Title Published Journal PubMed Link
Poehlsgaard J et al. Visualizing the 16-membered ring macrolides tildipirosin and tilmicosin bound to their ribosomal site. 2012 ACS Chem. Biol. pmid:22563863
Eguchi K et al. Establishment of evaluation method to determine effects of veterinary medicinal products on manure fermentation using small-scale composting apparatus. 2012 J. Biosci. Bioeng. pmid:22595343
Pakpour S et al. Frequency of antibiotic resistance in a swine facility 2.5 years after a ban on antibiotics. 2012 Microb. Ecol. pmid:21997543
Rérat M et al. Bovine respiratory disease: efficacy of different prophylactic treatments in veal calves and antimicrobial resistance of isolated Pasteurellaceae. 2012 Prev. Vet. Med. pmid:21945813
Apley MD et al. Use estimates of in-feed antimicrobials in swine production in the United States. 2012 Foodborne Pathog. Dis. pmid:22324295
Vandenberge V et al. Transfer of flubendazole and tylosin from feed at cross-contamination levels to various poultry matrices. 2012 Poult. Sci. pmid:22912473
Andersen NM et al. Inhibition of protein synthesis on the ribosome by tildipirosin compared with other veterinary macrolides. 2012 Antimicrob. Agents Chemother. pmid:22926570
Liu Y et al. Transcriptional profiling of Haemophilus parasuis SH0165 response to tilmicosin. 2012 Microb. Drug Resist. pmid:22935051
Kim HB et al. Microbial shifts in the swine distal gut in response to the treatment with antimicrobial growth promoter, tylosin. 2012 Proc. Natl. Acad. Sci. U.S.A. pmid:22955886
Menge M et al. Pharmacokinetics of tildipirosin in bovine plasma, lung tissue, and bronchial fluid (from live, nonanesthetized cattle). 2012 J. Vet. Pharmacol. Ther. pmid:22188102
Granados-Chinchilla F et al. A novel green chemistry method for nonaqueous extraction and high-performance liquid chromatography detection of first-, second-, and third-generation tetracyclines, 4-epitetracycline, and tylosin in animal feeds. 2012 J. Agric. Food Chem. pmid:22738432
Persoons D et al. Antimicrobial use in Belgian broiler production. 2012 Prev. Vet. Med. pmid:22459488
Kim HY et al. Biochemical effects of veterinary antibiotics on proliferation and cell cycle arrest of human HEK293 cells. 2012 Bull Environ Contam Toxicol pmid:22673765
Blondeau JM et al. Comparative minimum inhibitory and mutant prevention drug concentrations of enrofloxacin, ceftiofur, florfenicol, tilmicosin and tulathromycin against bovine clinical isolates of Mannheimia haemolytica. 2012 Vet. Microbiol. pmid:22677482
Sakai A et al. Production of a hybrid 16-membered macrolide antibiotic by genetic engineering of Micromonospora sp. TPMA0041. 2012 J. Ind. Microbiol. Biotechnol. pmid:22842988
Srinivasan P et al. Development of an HPLC method to analyze four veterinary antibiotics in soils and aqueous media and validation through fate studies. 2012 J Environ Sci Health A Tox Hazard Subst Environ Eng pmid:22871010
Er A and Yazar E Effects of tylosin, tilmicosin and tulathromycin on inflammatory mediators in bronchoalveolar lavage fluid of lipopolysaccharide-induced lung injury. 2012 Acta Vet. Hung. pmid:23160029
Westermarck E and Wiberg M Exocrine pancreatic insufficiency in the dog: historical background, diagnosis, and treatment. 2012 Top Companion Anim Med pmid:23148848
Peng D et al. Development and validation of an indirect competitive enzyme-linked immunosorbent assay for the screening of tylosin and tilmicosin in muscle, liver, milk, honey and eggs. 2012 J. Agric. Food Chem. pmid:22136611
Kim KR et al. Decline in extractable antibiotics in manure-based composts during composting. 2012 Waste Manag pmid:21865024