Tylosin

Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Tylosin?

Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Tylosin

MeSH term MeSH ID Detail
Bacillaceae Infections D016863 1 associated lipids
Mycotoxicosis D015651 5 associated lipids
Weight Gain D015430 101 associated lipids
Vasculitis D014657 14 associated lipids
Treponemal Infections D014211 3 associated lipids
Tracheal Diseases D014133 3 associated lipids
Swine Diseases D013553 16 associated lipids
Staphylococcal Skin Infections D013207 9 associated lipids
Pasteurellosis, Pneumonic D012766 3 associated lipids
Pyoderma D011711 5 associated lipids
Per page 10 20 50 | Total 47

PubChem Associated disorders and diseases

What pathways are associated with Tylosin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Tylosin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Tylosin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Tylosin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Tylosin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Tylosin?

Knock-out

Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Tylosin

Download all related citations
Per page 10 20 50 100 | Total 931
Authors Title Published Journal PubMed Link
Abdel-Daim MM et al. Synergistic protective role of mirazid (Commiphora molmol) and ascorbic acid against tilmicosin-induced cardiotoxicity in mice. 2015 Can. J. Physiol. Pharmacol. pmid:25429612
Paradis MA et al. Efficacy of tilmicosin in the control of experimentally induced Actinobacillus pleuropneumoniae infection in swine. 2004 Can. J. Vet. Res. pmid:14979429
Fittipaldi N et al. Assessment of the efficacy of tilmicosin phosphate to eliminate Actinobacillus pleuropneumoniae from carrier pigs. 2005 Can. J. Vet. Res. pmid:15971680
Goubau S et al. Tilmicosin does not inhibit interleukin-8 gene expression in the bovine lung experimentally infected with Mannheimia (Pasteurella) haemolytica. 2000 Can. J. Vet. Res. pmid:11041503
Dingwell RT et al. Influence of the genotype of Staphylococcus aureus, determined by pulsed-field gel electrophoresis, on dry-period elimination of subclinical mastitis in Canadian dairy herds. 2006 Can. J. Vet. Res. pmid:16639943
Brumbaugh GW et al. Susceptibility of Mycobacterium avium sbsp paratuberculosis to monensin sodium or tilmicosin phosphate in vitro and resulting infectivity in a murine model. 2004 Can. J. Vet. Res. pmid:15352541
Morck DW et al. Treatment of experimentally induced pneumonic pasteurellosis of young calves with tilmicosin. 1997 Can. J. Vet. Res. pmid:9242998
Buret AG Immuno-modulation and anti-inflammatory benefits of antibiotics: the example of tilmicosin. 2010 Can. J. Vet. Res. pmid:20357951
Burrows GE et al. Antibiotic disposition in experimental pneumonic pasteurellosis: gentamicin and tylosin. 1986 Can. J. Vet. Res. pmid:3756673
Scott DW et al. Efficacy of tylosin tablets for the treatment of pyoderma due to Staphylococcus intermedius infection in dogs. 1994 Can. Vet. J. pmid:7994702
Van Lunen TA Growth performance of pigs fed diets with and without tylosin phosphate supplementation and reared in a biosecure all-in all-out housing system. 2003 Can. Vet. J. pmid:12892287
Croft A et al. The effect of tilmicosin administered to ewes prior to lambing on incidence of clinical mastitis and subsequent lamb performance. 2000 Can. Vet. J. pmid:10769768
Van Donkersgoed J et al. The effect of administering long-acting oxytetracycline and tilmicosin either by dart gun or by hand on injection site lesions and drug residues in beef cattle. 1999 Can. Vet. J. pmid:12001341
Schunich OC et al. A comparison of prophylactic efficacy of tilmicosin and a new formulation of oxytetracycline in feedlot calves. 2002 Can. Vet. J. pmid:12001501
Abutarbush SM et al. Comparison of enrofloxacin and ceftiofur sodium for the treatment of relapse of undifferentiated fever/bovine respiratory disease in feedlot cattle. 2012 Can. Vet. J. pmid:22753964
Scott DW et al. Further studies on the efficacy of tylosin tablets for the treatment of pyoderma due to Staphylococcus intermedius infection in dogs. 1996 Can. Vet. J. pmid:8896878
Christodoulopoulos G Adverse outcome of using tilmicosin in a lamb with multiple ventricular septal defects. 2009 Can. Vet. J. pmid:19337615
Hoar BR et al. A comparison of the clinical field efficacy and safety of florfenicol and tilmicosin for the treatment of undifferentiated bovine respiratory disease of cattle in western Canada. 1998 Can. Vet. J. pmid:9524721
Barth AD and Wood MR The effect of streptomycin, oxytetracycline, tilmicosin and phenylbutazone on spermatogenesis in bulls. 1998 Can. Vet. J. pmid:10051958
Jim GK et al. A comparison of florfenicol and tilmicosin for the treatment of undifferentiated fever in feedlot calves in western Canada. 1999 Can. Vet. J. pmid:10086218