| MeSH term | MeSH ID | Detail |
|---|---|---|
| Bacillaceae Infections | D016863 | 1 associated lipids |
| Mycotoxicosis | D015651 | 5 associated lipids |
| Weight Gain | D015430 | 101 associated lipids |
| Vasculitis | D014657 | 14 associated lipids |
| Treponemal Infections | D014211 | 3 associated lipids |
| Tracheal Diseases | D014133 | 3 associated lipids |
| Swine Diseases | D013553 | 16 associated lipids |
| Staphylococcal Skin Infections | D013207 | 9 associated lipids |
| Pasteurellosis, Pneumonic | D012766 | 3 associated lipids |
| Pyoderma | D011711 | 5 associated lipids |
Tylosin
Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Tylosin?
Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (6)
- Appl. Environ. Microbiol. (2)
- Proc. Natl. Acad. Sci. U.S.A. (2)
- Others (6)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Tylosin
PubChem Associated disorders and diseases
What pathways are associated with Tylosin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Tylosin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Tylosin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Tylosin?
There are no associated biomedical information in the current reference collection.
What genes are associated with Tylosin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (9)
- Microbiology (Reading, Engl.) (3)
- Proc. Natl. Acad. Sci. U.S.A. (2)
- Others (13)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Tylosin?
Knock-out
Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with Tylosin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Lee SW et al. | Prevalence of porcine proliferative enteropathy and its control with tylosin in Korea. | 2001 | J. Vet. Sci. | pmid:12441690 |
| Kim D et al. | In vitro susceptibilities of Leptospira spp. and Borrelia burgdorferi isolates to amoxicillin, tilmicosin, and enrofloxacin. | 2006 | J. Vet. Sci. | pmid:17106227 |
| Fajt VR et al. | The effects of danofloxacin and tilmicosin on neutrophil function and lung consolidation in beef heifer calves with induced Pasteurella (Mannheimia) haemolytica pneumonia. | 2003 | J. Vet. Pharmacol. Ther. | pmid:12755900 |
| Fajt VR et al. | Effects of danofloxacin and tilmicosin on circulating neutrophils in beef heifers. | 2000 | J. Vet. Pharmacol. Ther. | pmid:11110107 |
| Ziv G et al. | Disposition kinetics of tylosin tartrate administered intravenously and intramuscularly to normal and water-deprived camels. | 1995 | J. Vet. Pharmacol. Ther. | pmid:8583543 |
| Ziv G et al. | Tilmicosin antibacterial activity and pharmacokinetics in cows. | 1995 | J. Vet. Pharmacol. Ther. | pmid:8587151 |
| Brown SA et al. | Characterization of plasma and lung concentrations after ceftiofur sodium and tilmicosin phosphate administered subcutaneously to mice. | 1995 | J. Vet. Pharmacol. Ther. | pmid:8587160 |
| Main BW et al. | Cardiovascular effects of the macrolide antibiotic tilmicosin, administered alone and in combination with propranolol or dobutamine, in conscious unrestrained dogs. | 1996 | J. Vet. Pharmacol. Ther. | pmid:8803881 |
| Canning P et al. | Concentrations of tylvalosin and 3-O-acetyltylosin attained in the synovial fluid of swine after administration by oral gavage at 50 and 5Â mg/kg. | 2016 | J. Vet. Pharmacol. Ther. | pmid:27086612 |
| Ling Z et al. | Preparation, characterization, and pharmacokinetics of tilmicosin- and florfenicol-loaded hydrogenated castor oil-solid lipid nanoparticles. | 2017 | J. Vet. Pharmacol. Ther. | pmid:27687707 |
| Menge M et al. | Pharmacokinetics of tildipirosin in bovine plasma, lung tissue, and bronchial fluid (from live, nonanesthetized cattle). | 2012 | J. Vet. Pharmacol. Ther. | pmid:22188102 |
| Wang J et al. | Pharmacokinetics of tildipirosin in beagle dogs. | 2018 | J. Vet. Pharmacol. Ther. | pmid:28892155 |
| Mohammadsadegh M | Impact of intramammary tilmicosin infusion as a dry cow therapy. | 2018 | J. Vet. Pharmacol. Ther. | pmid:28600854 |
| Han C et al. | Hydrogenated castor oil nanoparticles as carriers for the subcutaneous administration of tilmicosin: in vitro and in vivo studies. | 2009 | J. Vet. Pharmacol. Ther. | pmid:19290940 |
| Scorneaux B and Shryock TR | Intracellular accumulation, subcellular distribution and efflux of tilmicosin in swine phagocytes. | 1998 | J. Vet. Pharmacol. Ther. | pmid:9731947 |
| Scorneaux B and Shryock TR | The determination of the cellular volume of avian, porcine and bovine phagocytes and bovine mammary epithelial cells and its relationship to uptake of tilmicosin. | 1999 | J. Vet. Pharmacol. Ther. | pmid:10211711 |
| Cerdá RO et al. | Impact of the type of catheter on the absorption of tylvalosin (acetylvaleryltylosin) administered orally to broiler chickens. | 2010 | J. Vet. Pharmacol. Ther. | pmid:20444046 |
| Lombardi KR et al. | Pharmacokinetics of tilmicosin in beef cattle following intravenous and subcutaneous administration. | 2011 | J. Vet. Pharmacol. Ther. | pmid:21323676 |
| Modric S et al. | Pharmacokinetics and pharmacodynamics of tilmicosin in sheep and cattle. | 1998 | J. Vet. Pharmacol. Ther. | pmid:9885967 |
| Foster DM et al. | Comparison of direct sampling and brochoalveolar lavage for determining active drug concentrations in the pulmonary epithelial lining fluid of calves injected with enrofloxacin or tilmicosin. | 2017 | J. Vet. Pharmacol. Ther. | pmid:28457009 |