Tylosin

Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Tylosin?

Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Tylosin

MeSH term MeSH ID Detail
Foreign Bodies D005547 5 associated lipids
Hyperplasia D006965 34 associated lipids
Clostridium Infections D003015 5 associated lipids
Ataxia D001259 20 associated lipids
Staphylococcal Skin Infections D013207 9 associated lipids
Bacteriuria D001437 7 associated lipids
Pasteurella Infections D010326 8 associated lipids
Swine Diseases D013553 16 associated lipids
Poultry Diseases D011201 21 associated lipids
Vasculitis D014657 14 associated lipids
Per page 10 20 50 | Total 47

PubChem Associated disorders and diseases

What pathways are associated with Tylosin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Tylosin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Tylosin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Tylosin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Tylosin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Tylosin?

Knock-out

Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Tylosin

Download all related citations
Per page 10 20 50 100 | Total 931
Authors Title Published Journal PubMed Link
Jost BH et al. A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes. 2004 Antimicrob. Agents Chemother. pmid:14982756
Dotzlaf JE et al. Incorporation of amino acid-derived carbon into tylactone by Streptomyces fradiae GS14. 1984 Antimicrob. Agents Chemother. pmid:6424562
Collier CT et al. Effects of tylosin on bacterial mucolysis, Clostridium perfringens colonization, and intestinal barrier function in a chick model of necrotic enteritis. 2003 Antimicrob. Agents Chemother. pmid:14506046
Elkins CA and Mullis LB Substrate competition studies using whole-cell accumulation assays with the major tripartite multidrug efflux pumps of Escherichia coli. 2007 Antimicrob. Agents Chemother. pmid:17210767
Kobayashi H et al. Macrolide susceptibility of Mycoplasma hyorhinis isolated from piglets. 1996 Antimicrob. Agents Chemother. pmid:8849222
Shakya T and Wright GD Nucleotide selectivity of antibiotic kinases. 2010 Antimicrob. Agents Chemother. pmid:20231391
Hidalgo Á et al. Trends towards lower antimicrobial susceptibility and characterization of acquired resistance among clinical isolates of Brachyspira hyodysenteriae in Spain. 2011 Antimicrob. Agents Chemother. pmid:21555771
Rodionova II et al. [Effect of protoplast formation on the antibiotic activity of the Streptomyces fradiae 165 strain--a producer of tylosin]. 1987 Antibiot. Med. Biotekhnol. pmid:2830838
Panfilova ZI et al. [Obtaining of mutants of Streptomyces fradiae producing tylosin by action of nitrosomethylurea on synchronously germinating spores]. 1990 Antibiot. Khimioter. pmid:2383150
Malanicheva IA et al. [Protoplast fusion in Streptomyces fradiae strains producing neomycin and tylosin]. 1992 Antibiot. Khimioter. pmid:1296531