Tylosin

Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Tylosin?

Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Tylosin

MeSH term MeSH ID Detail
Mycotoxicosis D015651 5 associated lipids
Ureaplasma Infections D016869 5 associated lipids
Liver Abscess D008100 6 associated lipids
Mycoplasmatales Infections D009180 6 associated lipids
Pneumonia, Mycoplasma D011019 6 associated lipids
Facial Dermatoses D005148 7 associated lipids
Bacteriuria D001437 7 associated lipids
Lymphadenitis D008199 8 associated lipids
Pasteurella Infections D010326 8 associated lipids
Staphylococcal Skin Infections D013207 9 associated lipids
Campylobacter Infections D002169 13 associated lipids
Mycoplasma Infections D009175 13 associated lipids
Vasculitis D014657 14 associated lipids
Swine Diseases D013553 16 associated lipids
Pneumonia, Bacterial D018410 16 associated lipids
Ataxia D001259 20 associated lipids
Poultry Diseases D011201 21 associated lipids
Bacterial Infections D001424 21 associated lipids
Cattle Diseases D002418 24 associated lipids
Diarrhea D003967 32 associated lipids
Per page 10 20 50 | Total 47

PubChem Associated disorders and diseases

What pathways are associated with Tylosin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Tylosin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Tylosin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Tylosin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Tylosin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Tylosin?

Knock-out

Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Tylosin

Download all related citations
Per page 10 20 50 100 | Total 931
Authors Title Published Journal PubMed Link
Hartman EG and Geryl J Comparison between the minimal inhibitory concentration of tilmicosin and oxytetracycline for bovine pneumonic Pasteurella haemolytica isolates. 1993 Vet Q pmid:8122359
Voeten AC and Litjens JB The hygienic treatment of turkey eggs by dipping in an antibiotic and disinfectant solution. 1982 Vet Q pmid:7112889
Nagaraja TG and Lechtenberg KF Liver abscesses in feedlot cattle. 2007 Vet. Clin. North Am. Food Anim. Pract. pmid:17606156
Barbour EK et al. Impact of synergism of calcium phosphomycin/tylosin tartarate supplements on the performance of broilers in the Lebanon. 2010 Jan-Mar Vet. Ital. pmid:20391366
Short CR Comparative pharmacokinetics--sorting the sheep from the goats. 1999 Vet. J. pmid:10558834
Taha AA et al. Disposition kinetics of tylosin administered intravenously and intramuscularly in desert sheep and Nubian goats. 1999 Vet. J. pmid:10558841
Fodor L et al. Efficacy evaluations of the use of oral tilmicosin in pneumonic calves. 2000 Vet. J. pmid:10712808
Montesissa C et al. Metabolism of tilmicosin by rabbit liver microsomes and hepatocytes. 2004 Vet. J. pmid:14623156
Teixeira AGV et al. Efficacy of tildipirosin metaphylaxis for the prevention of respiratory disease, otitis and mortality in pre-weaned Holstein calves. 2017 Vet. J. pmid:28093111
Kilpinen S et al. Oral tylosin administration is associated with an increase of faecal enterococci and lactic acid bacteria in dogs with tylosin-responsive diarrhoea. 2015 Vet. J. pmid:26049259
Devreese M et al. Interaction between tylosin and bentonite clay from a pharmacokinetic perspective. 2012 Vet. J. pmid:22749117
Mitchell JD et al. In vitro pharmacodynamics of gamithromycin against Mycoplasma mycoides subspecies mycoides Small Colony. 2013 Vet. J. pmid:23810743
Wang XF et al. Enhancement of antibacterial activity of tilmicosin against Staphylococcus aureus by solid lipid nanoparticles in vitro and in vivo. 2012 Vet. J. pmid:21900026
Marks SL and Kather EJ Antimicrobial susceptibilities of canine Clostridium difficile and Clostridium perfringens isolates to commonly utilized antimicrobial drugs. 2003 Vet. Microbiol. pmid:12742714
Alippi AM et al. In vitro and in vivo susceptibility of the honeybee bacterial pathogen Paenibacillus larvae subsp. larvae to the antibiotic tylosin. 2005 Vet. Microbiol. pmid:15951140
Stipkovits L et al. A comparison of the effect of tiamulin hydrogen fumarate and tylosin tartrate on mycoplasmas of ruminants and some animal ureaplasmas. 1984 Vet. Microbiol. pmid:6730305
Juntunen P et al. Antimicrobial resistance in Campylobacter coli selected by tylosin treatment at a pig farm. 2010 Vet. Microbiol. pmid:20684867
Svartström O et al. Characterization of Treponema spp. isolates from pigs with ear necrosis and shoulder ulcers. 2013 Vet. Microbiol. pmid:23948134
Cornick NA Tylosin and chlorotetracycline decrease the duration of fecal shedding of E. coli O157:H7 by swine. 2010 Vet. Microbiol. pmid:20018464
Aarestrup FM and Jensen NE Susceptibility testing of Actinobacillus pleuropneumoniae in Denmark. Evaluation of three different media of MIC-determinations and tablet diffusion tests. 1999 Vet. Microbiol. pmid:10063535