Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.
To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Tylosin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Gandecha AR et al. | Analysis of four tylosin biosynthetic genes from the tylLM region of the Streptomyces fradiae genome. | 1997 | Gene | pmid:9031628 |
Baltz RH et al. | Applications of transposition mutagenesis in antibiotic producing streptomycetes. | 1997 | Antonie Van Leeuwenhoek | pmid:9049029 |
McFarland JW et al. | Repromicin derivatives with potent antibacterial activity against Pasteurella multocida. | 1997 | J. Med. Chem. | pmid:9083494 |
McFarland JW et al. | Quantitative structure-activity relationships among macrolide antibacterial agents: in vitro and in vivo potency against Pasteurella multocida. | 1997 | J. Med. Chem. | pmid:9135031 |
Memili E and Weisblum B | Essential role of endogenously synthesized tylosin for induction of ermSF in Streptomyces fradiae. | 1997 | Antimicrob. Agents Chemother. | pmid:9145902 |
Ramadan A | Pharmacokinetics of tilmicosin in serum and milk of goats. | 1997 Jan-Feb | Res. Vet. Sci. | pmid:9160424 |
Mironov VA et al. | [Effect of Ca2+ ions on biosynthesis and component composition of tylosin in Streptomyces fradiae]. | 1997 | Antibiot. Khimioter. | pmid:9182505 |
Morck DW et al. | Treatment of experimentally induced pneumonic pasteurellosis of young calves with tilmicosin. | 1997 | Can. J. Vet. Res. | pmid:9242998 |
Residues of some veterinary drugs in animals and foods. Monographs prepared by the Forty-Seventh meeting of the Joint FAO/WHO Expert Committee on Food Additives. Rome, 4-13 June 1996. | 1997 | FAO Food Nutr Pap | pmid:9253593 | |
Naranda A et al. | New dihydro and tetrahydro derivatives of desmycosin. III. The opening of oxirane ring of 12,13-epoxydesmycosin. | 1997 | J. Antibiot. | pmid:9402992 |