Tylosin

Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Tylosin?

Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Tylosin

MeSH term MeSH ID Detail
Lymphadenitis D008199 8 associated lipids
Mycoplasma Infections D009175 13 associated lipids
Mycoplasmatales Infections D009180 6 associated lipids
Occupational Diseases D009784 42 associated lipids
Pasteurella Infections D010326 8 associated lipids
Pneumonia, Mycoplasma D011019 6 associated lipids
Poultry Diseases D011201 21 associated lipids
Pyoderma D011711 5 associated lipids
Pasteurellosis, Pneumonic D012766 3 associated lipids
Staphylococcal Skin Infections D013207 9 associated lipids
Swine Diseases D013553 16 associated lipids
Tracheal Diseases D014133 3 associated lipids
Treponemal Infections D014211 3 associated lipids
Vasculitis D014657 14 associated lipids
Weight Gain D015430 101 associated lipids
Mycotoxicosis D015651 5 associated lipids
Bacillaceae Infections D016863 1 associated lipids
Ureaplasma Infections D016869 5 associated lipids
Neisseriaceae Infections D016870 3 associated lipids
Pneumonia, Bacterial D018410 16 associated lipids
Per page 10 20 50 | Total 47

PubChem Associated disorders and diseases

What pathways are associated with Tylosin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Tylosin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Tylosin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Tylosin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Tylosin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Tylosin?

Knock-out

Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Tylosin

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Per page 10 20 50 100 | Total 931
Authors Title Published Journal PubMed Link
Womble A et al. Pulmonary disposition of tilmicosin in foals and in vitro activity against Rhodococcus equi and other common equine bacterial pathogens. 2006 J. Vet. Pharmacol. Ther. pmid:17083461
Booker CW et al. An evaluation of the metaphylactic effect of ceftiofur crystalline free Acid in feedlot calves. 2006 Vet. Ther. pmid:17039449
Martínez MF and Barth AD Early detection and treatment of vesicular adenitis in bulls. 2007 Anim. Reprod. Sci. pmid:17027202
McAllister TA et al. Shedding of escherichia coli O157:H7 by cattle fed diets containing monensin or tylosin. 2006 J. Food Prot. pmid:16995508
Peng Z and Bang-Ce Y Small molecule microarrays for drug residue detection in foodstuffs. 2006 J. Agric. Food Chem. pmid:16968051
Bate N et al. Regulation of tylosin biosynthesis involving 'SARP-helper' activity. 2006 Mol. Microbiol. pmid:16942604
Industry guidance on the administration of tilmicosin. 2006 Vet. Rec. pmid:16924727
Chun S et al. Influence of agricultural antibiotics and 17beta-estradiol on the microbial community of soil. 2006 J Environ Sci Health B pmid:16893780
Residues of some veterinary drugs in animals and foods. Monographs prepared by the thirty-eighth meeting of the Joint FAO/WHO Expert Committee on Food Additives. 1991 FAO Food Nutr Pap pmid:1687815
Karahalios P et al. On the mechanism of action of 9-O-arylalkyloxime derivatives of 6-O-mycaminosyltylonolide, a new class of 16-membered macrolide antibiotics. 2006 Mol. Pharmacol. pmid:16873579
DiLorenzo N et al. Effects of feeding polyclonal antibody preparations on ruminal bacterial populations and ruminal pH of steers fed high-grain diets. 2006 J. Anim. Sci. pmid:16864880
Jiang H et al. Residue depletion of tilmicosin in cattle after subcutaneous administration. 2006 J. Agric. Food Chem. pmid:16819937
Allaire SE et al. Sorption kinetics of chlortetracyline and tylosin on sandy loam and heavy clay soils. 2006 Jul-Aug J. Environ. Qual. pmid:16738380
Yang S et al. Trace analysis and occurrence of anhydroerythromycin and tylosin in influent and effluent wastewater by liquid chromatography combined with electrospray tandem mass spectrometry. 2006 Anal Bioanal Chem pmid:16715282
García-Mayor MA et al. Liquid chromatography-UV diode-array detection method for multi-residue determination of macrolide antibiotics in sheep's milk. 2006 J Chromatogr A pmid:16682049
Cao XY et al. Tilmicosin and tylosin have anti-inflammatory properties via modulation of COX-2 and iNOS gene expression and production of cytokines in LPS-induced macrophages and monocytes. 2006 Int. J. Antimicrob. Agents pmid:16647840
Dingwell RT et al. Influence of the genotype of Staphylococcus aureus, determined by pulsed-field gel electrophoresis, on dry-period elimination of subclinical mastitis in Canadian dairy herds. 2006 Can. J. Vet. Res. pmid:16639943
Terui Y et al. Synthesis of 2-methyl 16-membered macrolide derived from tylosin. 2006 J. Antibiot. pmid:16629410
ter Laak TL et al. Estimation of soil sorption coefficients of veterinary pharmaceuticals from soil properties. 2006 Environ. Toxicol. Chem. pmid:16629132
ter Laak TL et al. The effect of pH and ionic strength on the sorption of sulfachloropyridazine, tylosin, and oxytetracycline to soil. 2006 Environ. Toxicol. Chem. pmid:16629129
Shakeri-Nejad K and Stahlmann R Drug interactions during therapy with three major groups of antimicrobial agents. 2006 Expert Opin Pharmacother pmid:16556082
Nozal Nalda MJ et al. Trace analysis of antibacterial tylosin A, B, C and D in honey by liquid chromatography-electrospray ionization-mass spectrometry. 2006 J Sep Sci pmid:16544883
Carlson JC and Mabury SA Dissipation kinetics and mobility of chlortetracycline, tylosin, and monensin in an agricultural soil in Northumberland County, Ontario, Canada. 2006 Environ. Toxicol. Chem. pmid:16494218
Jung WS et al. Heterologous expression of tylosin polyketide synthase and production of a hybrid bioactive macrolide in Streptomyces venezuelae. 2006 Appl. Microbiol. Biotechnol. pmid:16493552
Jacobsen AM and Halling-Sørensen B Multi-component analysis of tetracyclines, sulfonamides and tylosin in swine manure by liquid chromatography-tandem mass spectrometry. 2006 Anal Bioanal Chem pmid:16485090
Chelliapan S et al. Performance of an up-flow anaerobic stage reactor (UASR) in the treatment of pharmaceutical wastewater containing macrolide antibiotics. 2006 Water Res. pmid:16387347
Westermarck E et al. Effect of diet and tylosin on chronic diarrhea in beagles. 2005 Nov-Dec J. Vet. Intern. Med. pmid:16355675
Fu H et al. Synthesis and in vitro antibiotic activity of 16-membered 9-O-arylalkyloxime macrolides. 2006 Bioorg. Med. Chem. Lett. pmid:16343900
Beier RC et al. Production and characterization of monoclonal antibodies against the antibiotic tilmicosin. 2005 J. Agric. Food Chem. pmid:16332115
Ayling RD et al. Assessing the in vitro effectiveness of antimicrobials against Mycoplasma mycoides subsp. mycoides small-colony type to reduce contagious bovine pleuropneumonia infection. 2005 Antimicrob. Agents Chemother. pmid:16304194
Jensen LB and Aarestrup FM Regulation of the erm(C) gene in Staphylococci from reservoir with different usage of macrolides. 2005 Acta Vet. Scand. pmid:16261929
Mathieson PW et al. Mercuric chloride-treated brown Norway rats develop widespread tissue injury including necrotizing vasculitis. 1992 Lab. Invest. pmid:1625442
Pringle M et al. Tiamulin resistance in porcine Brachyspira pilosicoli isolates. 2006 Res. Vet. Sci. pmid:16253666
Rozeboom DW et al. Effects of mannan oligosaccharide and an antimicrobial product in nursery diets on performance of pigs reared on three different farms. 2005 J. Anim. Sci. pmid:16230663
Kumar K et al. Antibiotic uptake by plants from soil fertilized with animal manure. 2005 Nov-Dec J. Environ. Qual. pmid:16221828
Chander Y et al. Antibacterial activity of soil-bound antibiotics. 2005 Nov-Dec J. Environ. Qual. pmid:16221813
Brumbaugh GW et al. Effect of tilmicosin on chemotactic, phagocytic, and bactericidal activities of bovine and porcine alveolar macrophages. 2002 Am. J. Vet. Res. pmid:16206777
Clay SA et al. Tylosin sorption to silty clay loam soils, swine manure, and sand. 2005 J Environ Sci Health B pmid:16194921
Chun S et al. Effect of agricultural antibiotics on the persistence and transformation of 17beta-estradiol in a Sequatchie loam. 2005 J Environ Sci Health B pmid:16190018
Caldow M et al. Development and validation of an optical SPR biosensor assay for tylosin residues in honey. 2005 J. Agric. Food Chem. pmid:16159159
Skogerboe TL et al. Comparative efficacy of tulathromycin versus florfenicol and tilmicosin against undifferentiated bovine respiratory disease in feedlot cattle. 2005 Vet. Ther. pmid:16094565
Nutsch RG et al. Comparative efficacy of tulathromycin, tilmicosin, and florfenicol in the treatment of bovine respiratory disease in stocker cattle. 2005 Vet. Ther. pmid:16094564
Rooney KA et al. Efficacy of tulathromycin compared with tilmicosin and florfenicol for the control of respiratory disease in cattle at high risk of developing bovine respiratory disease. 2005 Vet. Ther. pmid:16094563
Kilgore WR et al. Therapeutic efficacy of tulathromycin, a novel triamilide antimicrobial, against bovine respiratory disease in feeder calves. 2005 Vet. Ther. pmid:16094562
Kilgore WR et al. Clinical effectiveness of tulathromycin, a novel triamilide antimicrobial, for the control of respiratory disease in cattle at high risk for developing bovine respiratory disease. 2005 Vet. Ther. pmid:16094561
Godinho KS et al. Efficacy of tulathromycin in the treatment and prevention of natural outbreaks of bovine respiratory disease in European cattle. 2005 Vet. Ther. pmid:16094560
Patterson J et al. Selected culturable enteric bacterial populations are modified by diet acidification and the growth promotant Tylosin. 2005 Lett. Appl. Microbiol. pmid:16033507
Shen J et al. Pharmacokinetics of tilmicosin after oral administration in swine. 2005 Am. J. Vet. Res. pmid:16008233
Forrester MB Human exposures to tilmicosin reported to poison centres, Texas, 1998-2003. 2005 Hum Exp Toxicol pmid:16004193
Fang XM et al. [A study on space mutation of Streptomyces fradiae]. 2005 Space Med Med Eng (Beijing) pmid:15977391