Tylosin

Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Tylosin?

Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Tylosin

MeSH term MeSH ID Detail
Lymphadenitis D008199 8 associated lipids
Mycoplasma Infections D009175 13 associated lipids
Mycoplasmatales Infections D009180 6 associated lipids
Occupational Diseases D009784 42 associated lipids
Pasteurella Infections D010326 8 associated lipids
Pneumonia, Mycoplasma D011019 6 associated lipids
Poultry Diseases D011201 21 associated lipids
Pyoderma D011711 5 associated lipids
Pasteurellosis, Pneumonic D012766 3 associated lipids
Staphylococcal Skin Infections D013207 9 associated lipids
Swine Diseases D013553 16 associated lipids
Tracheal Diseases D014133 3 associated lipids
Treponemal Infections D014211 3 associated lipids
Vasculitis D014657 14 associated lipids
Weight Gain D015430 101 associated lipids
Mycotoxicosis D015651 5 associated lipids
Bacillaceae Infections D016863 1 associated lipids
Ureaplasma Infections D016869 5 associated lipids
Neisseriaceae Infections D016870 3 associated lipids
Pneumonia, Bacterial D018410 16 associated lipids
Per page 10 20 50 | Total 47

PubChem Associated disorders and diseases

What pathways are associated with Tylosin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Tylosin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Tylosin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Tylosin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Tylosin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Tylosin?

Knock-out

Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Tylosin

Download all related citations
Per page 10 20 50 100 | Total 931
Authors Title Published Journal PubMed Link
Salamakha OV et al. [The study of the growth of tylosin producer using differential centrifugation of mycelium in a sucrose density gradient]. 1989 Sep-Oct Mikrobiologiia pmid:2635267
Cacciapuoti AF et al. Microbiological and pharmacokinetic studies of acyl demycinosyltylosin and related tylosin derivatives. 1990 J. Antibiot. pmid:2145254
Navashin SM et al. [Genetic and biochemical control of biosynthesis of macrolide antibiotics]. 1990 Antibiot. Khimioter. pmid:2078074
Fujiwara T and Takenaka S Bioconversion of 19-deformyl-5-O-desosaminyl tylonolide to 19-deformyl-4'-deoxydesmycosin (TMC-016). 1990 FEMS Microbiol. Lett. pmid:2379808
Roudaut B and Moretain JP Residues of macrolide antibiotics in eggs following medication of laying hens. 1990 Br. Poult. Sci. pmid:2245358
Morris FE et al. Effect of rotating monensin plus tylosin and lasalocid on performance, ruminal fermentation, and site and extent of digestion in feedlot cattle. 1990 J. Anim. Sci. pmid:2254185
MiliavskiÄ­ EB et al. [Electrophoretic separation of spores of producers of kanamycin and tylosin]. 1990 Antibiot. Khimioter. pmid:2334246
Fujiwara T et al. Absorption, tissue distribution and excretion of 19-deformyldesmycosin derivatives, new 16-membered macrolides, in mice. 1990 J. Antibiot. pmid:2324015
Panfilova ZI et al. [Obtaining of mutants of Streptomyces fradiae producing tylosin by action of nitrosomethylurea on synchronously germinating spores]. 1990 Antibiot. Khimioter. pmid:2383150
Collington GK et al. The influence of inclusion of either an antibiotic or a probiotic in the diet on the development of digestive enzyme activity in the pig. 1990 Br. J. Nutr. pmid:2119223
Huber ML et al. Branched-chain fatty acids produced by mutants of Streptomyces fradiae, putative precursors of the lactone ring of tylosin. 1990 Antimicrob. Agents Chemother. pmid:2221862
Coleman MR and Mowrey DH Turbidimetric assay of tylosin in animal feeds containing urea. 1990 Nov-Dec J Assoc Off Anal Chem pmid:2289924
Nakura H et al. Formation of an antibacterial metabolite from a new macrolide compound 23-O-benzyl-5-mycaminosyl-tylonolide (TMC-101), by a hepatic microsomal drug-metabolizing enzyme system. 1991 J. Pharmacobio-dyn. pmid:1802985
Rezanka T et al. Isobutyrate as a precursor of n-butyrate in the biosynthesis of tylosine and fatty acids. 1991 FEMS Microbiol. Lett. pmid:1769552
Rosteck PR et al. Homology between proteins controlling Streptomyces fradiae tylosin resistance and ATP-binding transport. 1991 Gene pmid:1864505
Lee SH and Lee KJ Relationship between threonine dehydratase and biosynthesis of tylosin in Streptomyces fradiae. 1991 J. Gen. Microbiol. pmid:1783901
Atef M et al. Disposition of tylosin in goats. 1991 DTW. Dtsch. Tierarztl. Wochenschr. pmid:1790764
Hue KK and Bechhofer DH Effect of ermC leader region mutations on induced mRNA stability. 1991 J. Bacteriol. pmid:1711026
Laven R and Andrews AH Long-acting antibiotic formulations in the treatment of calf pneumonia: a comparative study of tilmicosin and oxytetracycline. 1991 Vet. Rec. pmid:1926728
de Zwart MA et al. Synthesis and copper-dependent antimycoplasmal activity of amides and amidines derived from 2-amino-1,10-phenanthroline. 1991 J. Med. Chem. pmid:2002460