Tylosin

Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Tylosin?

Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Tylosin

MeSH term MeSH ID Detail
Poultry Diseases D011201 21 associated lipids
Pneumonia, Mycoplasma D011019 6 associated lipids
Pasteurella Infections D010326 8 associated lipids
Occupational Diseases D009784 42 associated lipids
Mycoplasmatales Infections D009180 6 associated lipids
Mycoplasma Infections D009175 13 associated lipids
Lymphadenitis D008199 8 associated lipids
Liver Abscess D008100 6 associated lipids
Keratoconjunctivitis, Infectious D007639 2 associated lipids
Hyperplasia D006965 34 associated lipids
Hemolysis D006461 131 associated lipids
Foreign Bodies D005547 5 associated lipids
Facial Dermatoses D005148 7 associated lipids
Erysipelothrix Infections D004889 1 associated lipids
Enterotoxemia D004767 1 associated lipids
Dysentery D004403 4 associated lipids
Diarrhea D003967 32 associated lipids
Conjunctivitis, Viral D003236 1 associated lipids
Colitis D003092 69 associated lipids
Clostridium Infections D003015 5 associated lipids
Per page 10 20 50 | Total 47

PubChem Associated disorders and diseases

What pathways are associated with Tylosin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Tylosin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Tylosin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Tylosin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Tylosin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Tylosin?

Knock-out

Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Tylosin

Download all related citations
Per page 10 20 50 100 | Total 931
Authors Title Published Journal PubMed Link
Meisel ML et al. Tylosin inhibits the steroidogenesis in mouse Leydig cells "in vitro". 1993 Life Sci. pmid:8390595
Kageyama S et al. Synthesis of 3-deoxy-3,4-didehydro derivatives of 5-O-mycaminosyltylonolide, 5-O-(4-deoxymycaminosyl) tylonolide, and desmycosin. 1993 J. Antibiot. pmid:8407589
Roets E et al. Quantitative analysis of tylosin by column liquid chromatography. 1993 J. Chromatogr. pmid:8445000
Migaki TT et al. Efficacy of danofloxacin and tylosin in the control of mycoplasmosis in chicks infected with tylosin-susceptible or tylosin-resistant field isolates of Mycoplasma gallisepticum. 1993 Apr-Jun Avian Dis. pmid:8395803
Tanner AC et al. A comparison of danofloxacin and tylosin in the control of induced Mycoplasma gallisepticum infection in broiler chicks. 1993 Apr-Jun Avian Dis. pmid:8395804
Meisel ML et al. Effects of tylosin on the pituitary-gonadal axis in male rats. 1993 Apr-May Pharmacol. Toxicol. pmid:8372057
Coleman MR et al. The need for larger analytical samples with granulated feed additives. 1993 Sep-Oct J AOAC Int pmid:8241822
McGuigan MA Human exposures to tilmicosin (MICOTIL). 1994 Vet Hum Toxicol pmid:7975134
Arisawa A et al. Cloning of the macrolide antibiotic biosynthesis gene acyA, which encodes 3-O-acyltransferase, from Streptomyces thermotolerans and its use for direct fermentative production of a hybrid macrolide antibiotic. 1994 Appl. Environ. Microbiol. pmid:8074537
Wardlaw AC et al. Bactericidal activity in the pig roundworm Ascaris suum. 1994 J. Appl. Bacteriol. pmid:8144403
Inouye M et al. Cloning and sequences of two macrolide-resistance-encoding genes from mycinamicin-producing Micromonospora griseorubida. 1994 Gene pmid:8163173
Scott PR Field study of undifferentiated respiratory disease in housed beef calves. 1994 Vet. Rec. pmid:8203107
Coronato S et al. A simple method to eliminate mycoplasma from cell cultures. 1994 J. Virol. Methods pmid:8175949
Kageyama S and Tsuchiya T Synthesis of 2-C-methyl derivatives of 3,4'-dideoxymycaminosyltylonolide, a novel type of 16-membered macrolide antibiotic. 1994 J. Antibiot. pmid:7928687
Trovatelli LD et al. The effect of some antibiotics on Enterococcus faecium SF 68 inoculated in germ-free mice. 1994 Microbiol. Res. pmid:7987613
Merson-Davies LA and Cundliffe E Analysis of five tylosin biosynthetic genes from the tyllBA region of the Streptomyces fradiae genome. 1994 Mol. Microbiol. pmid:7984112
Kelemen GH et al. Transcriptional attenuation control of the tylosin-resistance gene tlrA in Streptomyces fradiae. 1994 Mol. Microbiol. pmid:7534372
Caraffini S et al. Tylosin, an airborne contact allergen in veterinarians. 1994 Contact Derm. pmid:7867337
Lee SH and Lee KJ Kinetics of the repression of tylosin biosynthesis by ammonium ion in Streptomyces fradiae. 1994 J. Biotechnol. pmid:7764561
Danese P et al. Occupational contact dermatitis from tylosin. 1994 Contact Derm. pmid:8187499