Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.
To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Tylosin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Kim S | Failure of antibiotics gentamicin, tylosin, lincomycin and spectinomycin to eliminate Mycoplasma bovis in artificially infected frozen bovine semen. | 2000 | Theriogenology | pmid:10990359 |
Rosenbusch RF | Failure of antibiotics gentamicin, tylosin, lincomycin and spectinomycin (GTLS) to eliminate Mycoplasma bovis in artificially infected frozen bovine semen. | 2000 | Theriogenology | pmid:10990360 |
Thomas CB | Failure of antibiotics gentamicin, tylosin, lincomycin and spectinomycin (GTLS) to eliminate Mycoplasma bovis in artificially infected frozen bovine semen. | 2000 | Theriogenology | pmid:10990361 |
Stobba-Wiley CM et al. | Determination of tilmicosin residues in chicken, cattle, swine, and sheep tissues by liquid chromatography. | 2000 Jul-Aug | J AOAC Int | pmid:10995110 |
Dinos GP and Kalpaxis DL | Kinetic studies on the interaction between a ribosomal complex active in peptide bond formation and the macrolide antibiotics tylosin and erythromycin. | 2000 | Biochemistry | pmid:10995229 |
Goubau S et al. | Tilmicosin does not inhibit interleukin-8 gene expression in the bovine lung experimentally infected with Mannheimia (Pasteurella) haemolytica. | 2000 | Can. J. Vet. Res. | pmid:11041503 |
Mackie DP et al. | Mixed mycoplasma mastitis outbreak in a dairy herd. | 2000 | Vet. Rec. | pmid:11058024 |
Poulsen SM et al. | Inhibition of the ribosomal peptidyl transferase reaction by the mycarose moiety of the antibiotics carbomycin, spiramycin and tylosin. | 2000 | J. Mol. Biol. | pmid:11090288 |
DeRosa DC et al. | In vitro susceptibility of porcine respiratory pathogens to tilmicosin. | 2000 | J. Vet. Diagn. Invest. | pmid:11108454 |
Fajt VR et al. | Effects of danofloxacin and tilmicosin on circulating neutrophils in beef heifers. | 2000 | J. Vet. Pharmacol. Ther. | pmid:11110107 |
Frank GH and Duff GC | Effects of tilmicosin phosphate, administered prior to transport or at time of arrival, and feeding of chlortetracycline, after arrival in a feedlot, on Mannheimia haemolytica in nasal secretions of transported steers. | 2000 | Am. J. Vet. Res. | pmid:11131584 |
Nolan PM et al. | Maintenance of a captive flock of house finches free of infection by Mycoplasma gallisepticum. | 2000 Oct-Dec | Avian Dis. | pmid:11195652 |
Ingerslev F and Halling-Sørensen B | Biodegradability of metronidazole, olaquindox, and tylosin and formation of tylosin degradation products in aerobic soil--manure slurries. | 2001 | Ecotoxicol. Environ. Saf. | pmid:11222042 |
Ragheb HS | Antibiotics in feeds. | 2001 Jan-Feb | J AOAC Int | pmid:11234833 |
Butler AR et al. | Feedback control of polyketide metabolism during tylosin production. | 2001 | Microbiology (Reading, Engl.) | pmid:11283275 |
Morisaki N et al. | Glycosylative inactivation of chalcomycin and tylosin by a clinically isolated Nocardia asteroides strain. | 2001 | J. Antibiot. | pmid:11302489 |
Dinos GP et al. | Insights into the mechanism of azithromycin interaction with an Escherichia coli functional ribosomal complex. | 2001 | Mol. Pharmacol. | pmid:11353804 |
Whitehead TR and Cotta MA | Sequence analyses of a broad host-range plasmid containing ermT from a tylosin-resistant Lactobacillus sp. Isolated from swine feces. | 2001 | Curr. Microbiol. | pmid:11375658 |
Lim J and Yun H | Postantibiotic effects and postantibiotic sub-MIC effects of erythromycin, roxithromycin, tilmicosin, and tylosin on Pasteurella multocida. | 2001 | Int. J. Antimicrob. Agents | pmid:11397617 |
Wang C et al. | In vitro susceptibility of avian mycoplasmas to enrofloxacin, sarafloxacin, tylosin, and oxytetracycline. | 2001 Apr-Jun | Avian Dis. | pmid:11417828 |