Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.
To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Tylosin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Prats C et al. | Tylosin depletion from edible pig tissues. | 2002 | Res. Vet. Sci. | pmid:12443694 |
El-Ela FI et al. | Investigating the potential role of vitamin E in modulating the immunosuppressive effects of tylvalosin and florfenicol in broiler chickens. | 2016 | Res. Vet. Sci. | pmid:27663366 |
Pringle M et al. | Tiamulin resistance in porcine Brachyspira pilosicoli isolates. | 2006 | Res. Vet. Sci. | pmid:16253666 |
Goodwin RF | In vitro activity of tiamulin against porcine mycoplasmas. | 1985 | Res. Vet. Sci. | pmid:3975477 |
Reynaldi FJ et al. | [Binding of tylosin, tilmicosin and oxytetracycline to proteins from honeybees, larvae and beehive products]. | 2010 Oct-Dec | Rev. Argent. Microbiol. | pmid:21229198 |
Greer RT and Ryoo JP | Development of ocular inserts for cattle. | 1987 | Scanning Microsc. | pmid:3616580 |
Huwyler U et al. | Efficacy evaluation of the use of oral tilmicosin in pneumonic calves. | 1999 | Schweiz. Arch. Tierheilkd. | pmid:10228400 |
Xia X et al. | Proteomic analysis of tylosin-resistant Mycoplasma gallisepticum reveals enzymatic activities associated with resistance. | 2015 | Sci Rep | pmid:26584633 |
Brown K et al. | Antimicrobial growth promoters modulate host responses in mice with a defined intestinal microbiota. | 2016 | Sci Rep | pmid:27929072 |
Sura S et al. | Transport of three veterinary antimicrobials from feedlot pens via simulated rainfall runoff. | 2015 | Sci. Total Environ. | pmid:25839178 |
Luby EM et al. | Fate and transport of tylosin-resistant bacteria and macrolide resistance genes in artificially drained agricultural fields receiving swine manure. | 2016 | Sci. Total Environ. | pmid:26874610 |
Li Q et al. | Co-addition of manure increases the dissipation rates of tylosin A and the numbers of resistance genes in laboratory incubation experiments. | 2015 | Sci. Total Environ. | pmid:25958362 |
Ishikawa NK et al. | Determination of tylosin excretion from sheep to assess tylosin spread to agricultural fields by manure application. | 2018 | Sci. Total Environ. | pmid:29579651 |
Washington MT et al. | Monitoring tylosin and sulfamethazine in a tile-drained agricultural watershed using polar organic chemical integrative sampler (POCIS). | 2018 | Sci. Total Environ. | pmid:28854391 |
Srinivasan P et al. | Sorption of selected veterinary antibiotics onto dairy farming soils of contrasting nature. | 2014 | Sci. Total Environ. | pmid:24326064 |
Avci T and Elmas M | Milk and blood pharmacokinetics of tylosin and tilmicosin following parenteral administrations to cows. | 2014 | ScientificWorldJournal | pmid:25177733 |
Xie W et al. | [Determination of five macrolide antibiotic residues in royal jelly samples by using high performance liquid chromatography tandem mass spectrometry]. | 2007 | Se Pu | pmid:17679440 |
Horie M et al. | [Determination of spiramycin and tilmicosin in meat and fish by LC/MS]. | 2003 | Shokuhin Eiseigaku Zasshi | pmid:12968469 |
Fang XM et al. | [A study on space mutation of Streptomyces fradiae]. | 2005 | Space Med Med Eng (Beijing) | pmid:15977391 |
Solliec M et al. | Analysis of trimethoprim, lincomycin, sulfadoxin and tylosin in swine manure using laser diode thermal desorption-atmospheric pressure chemical ionization-tandem mass spectrometry. | 2014 | Talanta | pmid:25059125 |