Tylosin
Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Tylosin?
Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (6)
- Proc. Natl. Acad. Sci. U.S.A. (2)
- Appl. Environ. Microbiol. (2)
- Others (6)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Tylosin
PubChem Associated disorders and diseases
What pathways are associated with Tylosin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Tylosin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Tylosin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Tylosin?
There are no associated biomedical information in the current reference collection.
What genes are associated with Tylosin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (9)
- Microbiology (Reading, Engl.) (3)
- FEMS Microbiol. Lett. (2)
- Others (13)
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Tylosin?
Knock-out
Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with Tylosin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Jackson CR et al. | Effects of tylosin use on erythromycin resistance in enterococci isolated from swine. | 2004 | Appl. Environ. Microbiol. | pmid:15240302 |
| Lum AM et al. | Reverse engineering of industrial pharmaceutical-producing actinomycete strains using DNA microarrays. | 2004 | Metab. Eng. | pmid:15256208 |
| Mathers JJ et al. | Inhibition of resistance plasmid transfer in Escherichia coli by ionophores, chlortetracycline, bacitracin, and ionophore/antimicrobial combinations. | 2004 Apr-Jun | Avian Dis. | pmid:15283418 |
| Poole TL et al. | Competitive exclusion of a glycopeptide-resistant Enterococcus faecium in the presence of vancomycin but not equivalent concentrations of tylosin or gentamicin. | 2004 | Poult. Sci. | pmid:15285499 |
| Brumbaugh GW et al. | Susceptibility of Mycobacterium avium sbsp paratuberculosis to monensin sodium or tilmicosin phosphate in vitro and resulting infectivity in a murine model. | 2004 | Can. J. Vet. Res. | pmid:15352541 |
| Novotny GW et al. | Ketolide antimicrobial activity persists after disruption of interactions with domain II of 23S rRNA. | 2004 | Antimicrob. Agents Chemother. | pmid:15388419 |
| Kageyama S et al. | Synthesis of 3,4'-dideoxymycaminosyl tylonolide, a novel type of macrolide derivative. | 1992 | J. Antibiot. | pmid:1548187 |
| Civitareale C et al. | Identification and quantification method of spiramycin and tylosin in feedingstuffs with HPLC-UV/DAD at 1 ppm level. | 2004 | J Pharm Biomed Anal | pmid:15496324 |
| Elitok B and Elitok OM | Clinical efficacy of carprofen as an adjunct to the antibacterial treatment of bovine respiratory disease. | 2004 | J. Vet. Pharmacol. Ther. | pmid:15500569 |
| Clark C et al. | A preliminary investigation of the disposition of tilmicosin residues in elk tissues and serum. | 2004 | J. Vet. Pharmacol. Ther. | pmid:15500580 |
| Brain RA et al. | Aquatic microcosm assessment of the effects of tylosin on Lemna gibba and Myriophyllum spicatum. | 2005 | Environ. Pollut. | pmid:15519715 |
| Stratigopoulos G et al. | Positive control of tylosin biosynthesis: pivotal role of TylR. | 2004 | Mol. Microbiol. | pmid:15554972 |
| Kay P et al. | A lysimeter experiment to investigate the leaching of veterinary antibiotics through a clay soil and comparison with field data. | 2005 | Environ. Pollut. | pmid:15589660 |
| Rooklidge SJ et al. | Modeling antimicrobial contaminant removal in slow sand filtration. | 2005 Jan-Feb | Water Res. | pmid:15644241 |
| Thompson TS et al. | Determination of lincomycin and tylosin residues in honey by liquid chromatography/tandem mass spectrometry. | 2005 | Rapid Commun. Mass Spectrom. | pmid:15645470 |
| Menozzi A et al. | Effect of the macrolide antibacterial drug, tylosin, on TNBS-induced colitis in the rat. | 2005 | Pharmacology | pmid:15756055 |
| Kolz AC et al. | Degradation and metabolite production of tylosin in anaerobic and aerobic swine-manure lagoons. | 2005 Jan-Feb | Water Environ. Res. | pmid:15765935 |
| Wang J et al. | Determination of five macrolide antibiotic residues in eggs using liquid chromatography/electrospray ionization tandem mass spectrometry. | 2005 | J. Agric. Food Chem. | pmid:15769104 |
| Blackwell PA et al. | Evaluation of a lower tier exposure assessment model for veterinary medicines. | 2005 | J. Agric. Food Chem. | pmid:15769156 |
| Pfister P et al. | 23S rRNA base pair 2057-2611 determines ketolide susceptibility and fitness cost of the macrolide resistance mutation 2058A-->G. | 2005 | Proc. Natl. Acad. Sci. U.S.A. | pmid:15795375 |
| Westermarck E et al. | Tylosin-responsive chronic diarrhea in dogs. | 2005 Mar-Apr | J. Vet. Intern. Med. | pmid:15822561 |
| Lu L et al. | Autoinducer 2-like activity in poultry-associated enteric bacteria in response to subtherapeutic antibiotic exposure. | 2005 | Avian Dis. | pmid:15839416 |
| Loftin KA et al. | Inhibition of microbial metabolism in anaerobic lagoons by selected sulfonamides, tetracyclines, lincomycin, and tylosin tartrate. | 2005 | Environ. Toxicol. Chem. | pmid:15839550 |
| Halling-Sørensen B et al. | Dissipation and effects of chlortetracycline and tylosin in two agricultural soils: a field-scale study in southern Denmark. | 2005 | Environ. Toxicol. Chem. | pmid:15839553 |
| Liutskanova DG et al. | [Increase in tylosin production by a commercial strain of Streptomyces fradiae]. | 2005 Mar-Apr | Prikl. Biokhim. Mikrobiol. | pmid:15859462 |
| Yong H et al. | Design, synthesis and structure-activity relationships of 6-O-arylpropargyl diazalides with potent activity against multidrug-resistant Streptococcus pneumoniae. | 2005 | Bioorg. Med. Chem. Lett. | pmid:15863336 |
| Vicca J et al. | Efficacy of in-feed medication with tylosin for the treatment and control of Mycoplasma hyopneumoniae infections. | 2005 | Vet. Rec. | pmid:15879541 |
| Kolz AC et al. | Sorption of tylosin onto swine manure. | 2005 | Chemosphere | pmid:15914248 |
| Wu CM et al. | Induction of macrolide resistance in Mycoplasma gallisepticum in vitro and its resistance-related mutations within domain V of 23S rRNA. | 2005 | FEMS Microbiol. Lett. | pmid:15936901 |
| Alippi AM et al. | In vitro and in vivo susceptibility of the honeybee bacterial pathogen Paenibacillus larvae subsp. larvae to the antibiotic tylosin. | 2005 | Vet. Microbiol. | pmid:15951140 |
| Fittipaldi N et al. | Assessment of the efficacy of tilmicosin phosphate to eliminate Actinobacillus pleuropneumoniae from carrier pigs. | 2005 | Can. J. Vet. Res. | pmid:15971680 |
| Fang XM et al. | [A study on space mutation of Streptomyces fradiae]. | 2005 | Space Med Med Eng (Beijing) | pmid:15977391 |
| Forrester MB | Human exposures to tilmicosin reported to poison centres, Texas, 1998-2003. | 2005 | Hum Exp Toxicol | pmid:16004193 |
| Shen J et al. | Pharmacokinetics of tilmicosin after oral administration in swine. | 2005 | Am. J. Vet. Res. | pmid:16008233 |
| Patterson J et al. | Selected culturable enteric bacterial populations are modified by diet acidification and the growth promotant Tylosin. | 2005 | Lett. Appl. Microbiol. | pmid:16033507 |
| Godinho KS et al. | Efficacy of tulathromycin in the treatment and prevention of natural outbreaks of bovine respiratory disease in European cattle. | 2005 | Vet. Ther. | pmid:16094560 |
| Kilgore WR et al. | Clinical effectiveness of tulathromycin, a novel triamilide antimicrobial, for the control of respiratory disease in cattle at high risk for developing bovine respiratory disease. | 2005 | Vet. Ther. | pmid:16094561 |
| Kilgore WR et al. | Therapeutic efficacy of tulathromycin, a novel triamilide antimicrobial, against bovine respiratory disease in feeder calves. | 2005 | Vet. Ther. | pmid:16094562 |
| Rooney KA et al. | Efficacy of tulathromycin compared with tilmicosin and florfenicol for the control of respiratory disease in cattle at high risk of developing bovine respiratory disease. | 2005 | Vet. Ther. | pmid:16094563 |
| Nutsch RG et al. | Comparative efficacy of tulathromycin, tilmicosin, and florfenicol in the treatment of bovine respiratory disease in stocker cattle. | 2005 | Vet. Ther. | pmid:16094564 |
| Skogerboe TL et al. | Comparative efficacy of tulathromycin versus florfenicol and tilmicosin against undifferentiated bovine respiratory disease in feedlot cattle. | 2005 | Vet. Ther. | pmid:16094565 |
| Caldow M et al. | Development and validation of an optical SPR biosensor assay for tylosin residues in honey. | 2005 | J. Agric. Food Chem. | pmid:16159159 |
| Chun S et al. | Effect of agricultural antibiotics on the persistence and transformation of 17beta-estradiol in a Sequatchie loam. | 2005 | J Environ Sci Health B | pmid:16190018 |
| Clay SA et al. | Tylosin sorption to silty clay loam soils, swine manure, and sand. | 2005 | J Environ Sci Health B | pmid:16194921 |
| Brumbaugh GW et al. | Effect of tilmicosin on chemotactic, phagocytic, and bactericidal activities of bovine and porcine alveolar macrophages. | 2002 | Am. J. Vet. Res. | pmid:16206777 |
| Chander Y et al. | Antibacterial activity of soil-bound antibiotics. | 2005 Nov-Dec | J. Environ. Qual. | pmid:16221813 |
| Kumar K et al. | Antibiotic uptake by plants from soil fertilized with animal manure. | 2005 Nov-Dec | J. Environ. Qual. | pmid:16221828 |
| Rozeboom DW et al. | Effects of mannan oligosaccharide and an antimicrobial product in nursery diets on performance of pigs reared on three different farms. | 2005 | J. Anim. Sci. | pmid:16230663 |
| Pringle M et al. | Tiamulin resistance in porcine Brachyspira pilosicoli isolates. | 2006 | Res. Vet. Sci. | pmid:16253666 |
| Mathieson PW et al. | Mercuric chloride-treated brown Norway rats develop widespread tissue injury including necrotizing vasculitis. | 1992 | Lab. Invest. | pmid:1625442 |