Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.
To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Tylosin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Navashin SM et al. | [Genetic and biochemical control of biosynthesis of macrolide antibiotics]. | 1990 | Antibiot. Khimioter. | pmid:2078074 |
Panfilova ZI et al. | [Obtaining of mutants of Streptomyces fradiae producing tylosin by action of nitrosomethylurea on synchronously germinating spores]. | 1990 | Antibiot. Khimioter. | pmid:2383150 |
Esipov SE | [Novel mathematical approach to determination of antibiotics concentration by agar diffusion method. Analysis of graphical, table and mathematical options of relative biological activity estimation]. | 1998 | Antibiot. Khimioter. | pmid:9606490 |
Rodionova II et al. | [Effect of protoplast formation on the antibiotic activity of the Streptomyces fradiae 165 strain--a producer of tylosin]. | 1987 | Antibiot. Med. Biotekhnol. | pmid:2830838 |
Szczepanowski R et al. | Novel macrolide resistance module carried by the IncP-1beta resistance plasmid pRSB111, isolated from a wastewater treatment plant. | 2007 | Antimicrob. Agents Chemother. | pmid:17101677 |
Andersen NM et al. | Inhibition of protein synthesis on the ribosome by tildipirosin compared with other veterinary macrolides. | 2012 | Antimicrob. Agents Chemother. | pmid:22926570 |
Robredo B et al. | From vanA Enterococcus hirae to vanA Enterococcus faecium: a study of feed supplementation with avoparcin and tylosin in young chickens. | 1999 | Antimicrob. Agents Chemother. | pmid:10223926 |
Huber ML et al. | Branched-chain fatty acids produced by mutants of Streptomyces fradiae, putative precursors of the lactone ring of tylosin. | 1990 | Antimicrob. Agents Chemother. | pmid:2221862 |
Antunes NT et al. | In vitro susceptibilities of Mycoplasma putrefaciens field isolates. | 2007 | Antimicrob. Agents Chemother. | pmid:17638695 |
Bailey M et al. | Induction of erm(C) expression by noninducing antibiotics. | 2008 | Antimicrob. Agents Chemother. | pmid:18086834 |