Tylosin

Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Tylosin?

Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Tylosin

MeSH term MeSH ID Detail
Pyoderma D011711 5 associated lipids
Lymphadenitis D008199 8 associated lipids
Campylobacter Infections D002169 13 associated lipids
Mycoplasma Infections D009175 13 associated lipids
Pasteurellosis, Pneumonic D012766 3 associated lipids
Pneumonia, Bacterial D018410 16 associated lipids
Liver Abscess D008100 6 associated lipids
Treponemal Infections D014211 3 associated lipids
Dysentery D004403 4 associated lipids
Mycoplasmatales Infections D009180 6 associated lipids
Mycotoxicosis D015651 5 associated lipids
Porcine Reproductive and Respiratory Syndrome D019318 4 associated lipids
Ureaplasma Infections D016869 5 associated lipids
Pneumonia, Mycoplasma D011019 6 associated lipids
Tracheal Diseases D014133 3 associated lipids
Bacillaceae Infections D016863 1 associated lipids
Erysipelothrix Infections D004889 1 associated lipids
Keratoconjunctivitis, Infectious D007639 2 associated lipids
Neisseriaceae Infections D016870 3 associated lipids
Conjunctivitis, Viral D003236 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Tylosin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Tylosin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Tylosin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Tylosin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Tylosin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Tylosin?

Knock-out

Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Tylosin

Download all related citations
Per page 10 20 50 100 | Total 931
Authors Title Published Journal PubMed Link
Althaus RL et al. Detection limits of antimicrobials in ewe milk by delvotest photometric measurements. 2003 J. Dairy Sci. pmid:12647952
Iveković D et al. Electrochemical reduction of desmycosin, structure investigation and antibacterial evaluation of the resulting products. 2003 Eur J Pharm Sci pmid:12694884
Rodriguez E et al. Rapid engineering of polyketide overproduction by gene transfer to industrially optimized strains. 2003 J. Ind. Microbiol. Biotechnol. pmid:12698320
De Liguoro M et al. Use of oxytetracycline and tylosin in intensive calf farming: evaluation of transfer to manure and soil. 2003 Chemosphere pmid:12729703
Marks SL and Kather EJ Antimicrobial susceptibilities of canine Clostridium difficile and Clostridium perfringens isolates to commonly utilized antimicrobial drugs. 2003 Vet. Microbiol. pmid:12742714
Fajt VR et al. The effects of danofloxacin and tilmicosin on neutrophil function and lung consolidation in beef heifer calves with induced Pasteurella (Mannheimia) haemolytica pneumonia. 2003 J. Vet. Pharmacol. Ther. pmid:12755900
Neiffer DL Clostridium perfringens enterotoxicosis in two Amur leopards (Panthera pardus orientalis). 2001 J. Zoo Wildl. Med. pmid:12790411
Anderegg TR and Jones RN Initial disk diffusion quality control guidelines for tylosin tested against Staphylococcus aureus ATCC 25923 and Streptococcus pneumoniae ATCC 49619. 2003 Int. J. Antimicrob. Agents pmid:12791478
Tarabla H and Canavesio V Prevalence of intramammary infections by major pathogens at parturition in dairy cows after intramuscular antibiotic therapy at drying-off: a preliminary report. 2003 J. Dairy Res. pmid:12800878
Loria GR et al. In vitro susceptibilities of field isolates of Mycoplasma agalactiae to oxytetracycline, tylosin, enrofloxacin, spiramycin and lincomycin-spectinomycin. 2003 Res. Vet. Sci. pmid:12801456
Von Essen S et al. Unintentional human exposure to tilmicosin (Micotil 300). 2003 J. Toxicol. Clin. Toxicol. pmid:12807303
Del Vecchio F et al. Active-site residue, domain and module swaps in modular polyketide synthases. 2003 J. Ind. Microbiol. Biotechnol. pmid:12811585
Teeter JS and Meyerhoff RD Aerobic degradation of tylosin in cattle, chicken, and swine excreta. 2003 Environ. Res. pmid:12865047
Creemer LC et al. Facile synthesis of tilmicosin and tylosin related haptens for use as protein conjugates. 2003 J. Antibiot. pmid:12870814
Van Lunen TA Growth performance of pigs fed diets with and without tylosin phosphate supplementation and reared in a biosecure all-in all-out housing system. 2003 Can. Vet. J. pmid:12892287
Moubareck C et al. Multiple antibiotic resistance gene transfer from animal to human enterococci in the digestive tract of gnotobiotic mice. 2003 Antimicrob. Agents Chemother. pmid:12937011
Malanicheva IA et al. [Protoplast fusion in Streptomyces fradiae strains producing neomycin and tylosin]. 1992 Antibiot. Khimioter. pmid:1296531
Horie M et al. [Determination of spiramycin and tilmicosin in meat and fish by LC/MS]. 2003 Shokuhin Eiseigaku Zasshi pmid:12968469
Baltz RH et al. Transposition of Tn5096 and related transposons in Streptomyces species. 1992 Gene pmid:1319378
Kempf I et al. Efficacy of danofloxacin in the therapy of experimental mycoplasmosis in chicks. 1992 Res. Vet. Sci. pmid:1332154