Tylosin

Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Tylosin?

Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Tylosin

MeSH term MeSH ID Detail
Pyoderma D011711 5 associated lipids
Lymphadenitis D008199 8 associated lipids
Campylobacter Infections D002169 13 associated lipids
Mycoplasma Infections D009175 13 associated lipids
Pasteurellosis, Pneumonic D012766 3 associated lipids
Pneumonia, Bacterial D018410 16 associated lipids
Liver Abscess D008100 6 associated lipids
Treponemal Infections D014211 3 associated lipids
Dysentery D004403 4 associated lipids
Mycoplasmatales Infections D009180 6 associated lipids
Mycotoxicosis D015651 5 associated lipids
Porcine Reproductive and Respiratory Syndrome D019318 4 associated lipids
Ureaplasma Infections D016869 5 associated lipids
Pneumonia, Mycoplasma D011019 6 associated lipids
Tracheal Diseases D014133 3 associated lipids
Bacillaceae Infections D016863 1 associated lipids
Erysipelothrix Infections D004889 1 associated lipids
Keratoconjunctivitis, Infectious D007639 2 associated lipids
Neisseriaceae Infections D016870 3 associated lipids
Conjunctivitis, Viral D003236 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Tylosin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Tylosin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Tylosin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Tylosin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Tylosin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Tylosin?

Knock-out

Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Tylosin

Download all related citations
Per page 10 20 50 100 | Total 931
Authors Title Published Journal PubMed Link
Lee WD et al. Tilmicosin-induced bovine neutrophil apoptosis is cell-specific and downregulates spontaneous LTB4 synthesis without increasing Fas expression. 2004 Mar-Apr Vet. Res. pmid:15099497
Abu-Basha EA et al. Pharmacokinetics of tilmicosin (Provitil powder and Pulmotil liquid AC) oral formulations in chickens. 2007 Vet. Res. Commun. pmid:17225089
Gallina G et al. Acute toxicity evaluation of four antibacterials with Daphnia magna. 2008 Vet. Res. Commun. pmid:18688742
Gallina G et al. Kinetics and intrapulmonary disposition of tilmicosin after single and repeated oral bolus administrations to rabbits. 2010 Vet. Res. Commun. pmid:20480234
Saurit AR et al. Some comparative aspects of the pharmacokinetics of tylosin in buffaloes and cattle. 2002 Vet. Res. Commun. pmid:11860087
Lakritz J et al. Tilmicosin reduces lipopolysaccharide-stimulated bovine alveolar macrophage prostaglandin E(2) production via a mechanism involving phospholipases. 2002 Vet. Ther. pmid:12050824
Hibbard B et al. Dose determination and confirmation for ceftiofur crystalline-free acid administered in the posterior aspect of the ear for control and treatment of bovine respiratory disease. 2002 Vet. Ther. pmid:12050825
Nickell JS et al. Comparison of short-term health and performance effects related to prophylactic administration of tulathromycin versus tilmicosin in long-hauled, highly stressed beef stocker calves. 2008 Vet. Ther. pmid:18597253
Scott BA et al. Efficacy of tylosin tartrate on canine Staphylococcus intermedius isolates in vitro. 2010 Vet. Ther. pmid:20960412
Thacker EL et al. Evaluation of the ability of tilmicosin to prevent adherence of Mycoplasma hyopneumoniae to cilia using a differentiated swine respiratory epithelial culture system. 2001 Vet. Ther. pmid:19746651