| MeSH term | MeSH ID | Detail |
|---|---|---|
| Foreign Bodies | D005547 | 5 associated lipids |
| Hyperplasia | D006965 | 34 associated lipids |
| Clostridium Infections | D003015 | 5 associated lipids |
| Ataxia | D001259 | 20 associated lipids |
| Staphylococcal Skin Infections | D013207 | 9 associated lipids |
| Bacteriuria | D001437 | 7 associated lipids |
| Pasteurella Infections | D010326 | 8 associated lipids |
| Swine Diseases | D013553 | 16 associated lipids |
| Poultry Diseases | D011201 | 21 associated lipids |
| Vasculitis | D014657 | 14 associated lipids |
Tylosin
Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Tylosin?
Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (6)
- Appl. Environ. Microbiol. (2)
- Proc. Natl. Acad. Sci. U.S.A. (2)
- Others (6)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Tylosin
PubChem Associated disorders and diseases
What pathways are associated with Tylosin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Tylosin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Tylosin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Tylosin?
There are no associated biomedical information in the current reference collection.
What genes are associated with Tylosin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (9)
- Microbiology (Reading, Engl.) (3)
- Proc. Natl. Acad. Sci. U.S.A. (2)
- Others (13)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Tylosin?
Knock-out
Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with Tylosin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Hamscher G et al. | Quantitative analysis of tylosin in eggs by high performance liquid chromatography with electrospray ionization tandem mass spectrometry: residue depletion kinetics after administration via feed and drinking water in laying hens. | 2006 | J. Agric. Food Chem. | pmid:17117786 |
| Bhalsod GD et al. | Uptake and Accumulation of Pharmaceuticals in Overhead- and Surface-Irrigated Greenhouse Lettuce. | 2018 | J. Agric. Food Chem. | pmid:29293328 |
| Van Poucke C et al. | Tylosin detection in animal feed by liquid chromatography-tandem mass spectrometry with enzymatic hydrolysis of the tylosin urea adduct. | 2004 | J. Agric. Food Chem. | pmid:15137817 |
| Kart A et al. | The possible protective effect of L-carnitine on tilmicosin-induced cardiotoxicity in mice. | 2007 | J Vet Med A Physiol Pathol Clin Med | pmid:17381679 |
| Litterio NJ et al. | Microbiological screening test validation for detection of tylosin excretion in milk of cows with low and high somatic cell counts. | 2007 | J Vet Med A Physiol Pathol Clin Med | pmid:17359452 |
| Nozal Nalda MJ et al. | Trace analysis of antibacterial tylosin A, B, C and D in honey by liquid chromatography-electrospray ionization-mass spectrometry. | 2006 | J Sep Sci | pmid:16544883 |
| Sehati N et al. | Extraction and preconcentration of tylosin from milk samples through functionalized TiOâ‚‚ nanoparticles reinforced with a hollow fiber membrane as a novel solid/liquid-phase microextraction technique. | 2014 | J Sep Sci | pmid:24890459 |
| Liu YM et al. | Sensitive determination of tilmicosin, erythromycin ethylsuccinate and clindamycin by CE with electrochemiluminescence detection using azithromycin as internal standard and its applications. | 2010 | J Sep Sci | pmid:20235137 |
| Ashenafi D et al. | An improved liquid chromatographic method for the analysis of tylosin and its impurities. | 2011 | J Sep Sci | pmid:21812113 |
| Thurman GD et al. | Diagnosis and successful treatment of subacute erysipelas in a captive dolphin. | 1983 | J S Afr Vet Assoc | pmid:6655661 |
| Gummow B et al. | The diagnosis and treatment of bovine genital ureaplasmosis: a case study. | 1992 | J S Afr Vet Assoc | pmid:1404223 |
| Duthu GS | Interspecies correlation of the pharmacokinetics of erythromycin, oleandomycin, and tylosin. | 1985 | J Pharm Sci | pmid:4067847 |
| Pérez RA et al. | Analysis of macrolide antibiotics in water by magnetic solid-phase extraction and liquid chromatography-tandem mass spectrometry. | 2017 | J Pharm Biomed Anal | pmid:28858671 |
| Civitareale C et al. | Identification and quantification method of spiramycin and tylosin in feedingstuffs with HPLC-UV/DAD at 1 ppm level. | 2004 | J Pharm Biomed Anal | pmid:15496324 |
| Paesen J et al. | Study of the stability of tylosin A in aqueous solutions. | 1995 | J Pharm Biomed Anal | pmid:8573642 |
| Danielson ND et al. | Simple methods for the qualitative identification and quantitative determination of macrolide antibiotics. | 1993 | J Pharm Biomed Anal | pmid:8504183 |
| González de la Huebra MJ et al. | Sample preparation strategy for the simultaneous determination of macrolide antibiotics in animal feedingstuffs by liquid chromatography with electrochemical detection (HPLC-ECD). | 2007 | J Pharm Biomed Anal | pmid:17257795 |
| Oakes J and Seifert S | American association of poison control centers database characterization of human tilmicosin exposures, 2001-2005. | 2008 | J Med Toxicol | pmid:19031373 |
| Kolanović BS et al. | Tylosin content in meat and honey samples over a two-year period in Croatia. | 2014 | J Immunoassay Immunochem | pmid:24063615 |
| Krokidis M et al. | The slow dissociation rate of K-1602 contributes to the enhanced inhibitory activity of this novel alkyl-aryl-bearing fluoroketolide. | 2016 | J Enzyme Inhib Med Chem | pmid:25807301 |
| Chun S et al. | Influence of agricultural antibiotics and 17beta-estradiol on the microbial community of soil. | 2006 | J Environ Sci Health B | pmid:16893780 |
| Chun S et al. | Effect of agricultural antibiotics on the persistence and transformation of 17beta-estradiol in a Sequatchie loam. | 2005 | J Environ Sci Health B | pmid:16190018 |
| Clay SA et al. | Tylosin sorption to silty clay loam soils, swine manure, and sand. | 2005 | J Environ Sci Health B | pmid:16194921 |
| Hoese A et al. | Chlortetracycline and tylosin runoff from soils treated with antimicrobial containing manure. | 2009 | J Environ Sci Health B | pmid:19365753 |
| Stone JJ et al. | Land application of tylosin and chlortetracycline swine manure: Impacts to soil nutrients and soil microbial community structure. | 2011 | J Environ Sci Health B | pmid:21877979 |
| Srinivasan P et al. | Development of an HPLC method to analyze four veterinary antibiotics in soils and aqueous media and validation through fate studies. | 2012 | J Environ Sci Health A Tox Hazard Subst Environ Eng | pmid:22871010 |
| Guo X et al. | Sorption of tylosin and sulfamethazine on solid humic acid. | 2016 | J Environ Sci (China) | pmid:27155426 |
| Hu D and Coats JR | Laboratory evaluation of mobility and sorption for the veterinary antibiotic, tylosin, in agricultural soils. | 2009 | J Environ Monit | pmid:19724833 |
| Lust EB et al. | Human health hazards of veterinary medications: information for emergency departments. | 2011 | J Emerg Med | pmid:20045604 |
| Paesen J et al. | Isolation of decomposition products of tylosin using liquid chromatography. | 1995 | J Chromatogr A | pmid:7757214 |
| GarcÃa-Mayor MA et al. | Liquid chromatography-UV diode-array detection method for multi-residue determination of macrolide antibiotics in sheep's milk. | 2006 | J Chromatogr A | pmid:16682049 |
| Thompson TS et al. | Determination of lincomycin and tylosin residues in honey using solid-phase extraction and liquid chromatography-atmospheric pressure chemical ionization mass spectrometry. | 2003 | J Chromatogr A | pmid:14661747 |
| Sehati N et al. | Application of hollow fiber membrane mediated with titanium dioxide nanowire/reduced graphene oxide nanocomposite in preconcentration of clotrimazole and tylosin. | 2015 | J Chromatogr A | pmid:26477522 |
| Tobback K et al. | Micellar electrokinetic capillary chromatography of macrolide antibiotics. Separation of tylosin, erythromycin and their related substances. | 1999 | J Chromatogr A | pmid:10536850 |
| Draisci R et al. | Confirmatory method for macrolide residues in bovine tissues by micro-liquid chromatography-tandem mass spectrometry. | 2001 | J Chromatogr A | pmid:11554423 |
| Coleman MR and Mowrey DH | Turbidimetric assay of tylosin in animal feeds containing urea. | 1990 Nov-Dec | J Assoc Off Anal Chem | pmid:2289924 |
| Moats WA et al. | Comparison of liquid chromatographic and bioassay procedures for determining depletion of intramuscularly injected tylosin. | 1985 May-Jun | J Assoc Off Anal Chem | pmid:4019360 |
| Moats WA | Chromatographic methods for determination of macrolide antibiotic residues in tissues and milk of food-producing animals. | 1985 Sep-Oct | J Assoc Off Anal Chem | pmid:4055648 |
| Coleman MR et al. | The need for larger analytical samples with granulated feed additives. | 1993 Sep-Oct | J AOAC Int | pmid:8241822 |
| Clark SB et al. | Interlaboratory comparison of methods for the determination of incurred tilmicosin residues in bovine liver. | 2002 Nov-Dec | J AOAC Int | pmid:12477187 |
| Dudriková E et al. | Liquid chromatographic determination of tylosin in mastitic cow's milk following therapy. | 1999 Nov-Dec | J AOAC Int | pmid:10589481 |
| Ngoh MA | Determination of tilmicosin in bovine milk by liquid chromatography with ultraviolet detection. | 1996 May-Jun | J AOAC Int | pmid:8634534 |
| Stobba-Wiley CM et al. | Determination of tilmicosin residues in chicken, cattle, swine, and sheep tissues by liquid chromatography. | 2000 Jul-Aug | J AOAC Int | pmid:10995110 |
| Readnour RS et al. | Liquid chromatographic determination of tilmicosin in swine feed at 200-400 mg/kg level: interlaboratory study. | 1997 Nov-Dec | J AOAC Int | pmid:9419853 |
| Readnour RS et al. | Determination of tilmicosin in swine feeds by liquid chromatography. | 1997 Nov-Dec | J AOAC Int | pmid:9419854 |
| Moran JW et al. | Determination of tilmicosin in bovine and porcine sera by liquid chromatography. | 1997 Nov-Dec | J AOAC Int | pmid:9419857 |
| Gramse MJ et al. | Determination of tylosin in feeds by liquid chromatography with solid-phase extraction. | 2004 Mar-Apr | J AOAC Int | pmid:15164825 |
| Markakis PK | Microbiological method for determining macrolides in animal feeds in the presence of other drugs by thin-layer chromatography detection. | 1996 Nov-Dec | J AOAC Int | pmid:8946704 |
| Granja R et al. | Determination of erythromycin and tylosin residues in honey by LC/MS/MS. | 2009 May-Jun | J AOAC Int | pmid:19610392 |
| Ragheb HS | Antibiotics in feeds. | 2001 Jan-Feb | J AOAC Int | pmid:11234833 |