| MeSH term | MeSH ID | Detail |
|---|---|---|
| Foreign Bodies | D005547 | 5 associated lipids |
| Hyperplasia | D006965 | 34 associated lipids |
| Clostridium Infections | D003015 | 5 associated lipids |
| Ataxia | D001259 | 20 associated lipids |
| Staphylococcal Skin Infections | D013207 | 9 associated lipids |
| Bacteriuria | D001437 | 7 associated lipids |
| Pasteurella Infections | D010326 | 8 associated lipids |
| Swine Diseases | D013553 | 16 associated lipids |
| Poultry Diseases | D011201 | 21 associated lipids |
| Vasculitis | D014657 | 14 associated lipids |
Tylosin
Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Tylosin?
Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (6)
- Proc. Natl. Acad. Sci. U.S.A. (2)
- Appl. Environ. Microbiol. (2)
- Others (6)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Tylosin
PubChem Associated disorders and diseases
What pathways are associated with Tylosin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Tylosin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Tylosin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Tylosin?
There are no associated biomedical information in the current reference collection.
What genes are associated with Tylosin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (9)
- Microbiology (Reading, Engl.) (3)
- FEMS Microbiol. Lett. (2)
- Others (13)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Tylosin?
Knock-out
Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with Tylosin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Paraud C et al. | Evaluation of oral tilmicosin efficacy against severe cryptosporidiosis in neonatal kids under field conditions. | 2010 | Vet. Parasitol. | pmid:20149542 |
| Er A et al. | Effects of tylosin on serum cytokine levels in healthy and lipopolysaccharide-treated mice. | 2010 | Acta Vet. Hung. | pmid:20159741 |
| Van Donkersgoed J et al. | Drug residues recovered in feed after various feedlot mixer truck cleanout procedures. | 2010 | J. Food Prot. | pmid:20051207 |
| Lindemann MD et al. | Evaluation of antibiotic effects on phosphorus digestibility and utilization by growing-finishing pigs fed a phosphorus-deficient, corn-soybean meal diet. | 2010 | J. Anim. Sci. | pmid:20081078 |
| Elkins CA et al. | Single nucleotide polymorphism analysis of the major tripartite multidrug efflux pump of Escherichia coli: functional conservation in disparate animal reservoirs despite exposure to antimicrobial chemotherapy. | 2010 | Antimicrob. Agents Chemother. | pmid:20038628 |
| Barbour EK et al. | Impact of synergism of calcium phosphomycin/tylosin tartarate supplements on the performance of broilers in the Lebanon. | 2010 Jan-Mar | Vet. Ital. | pmid:20391366 |
| Sumbatian NV et al. | [Amino acid and peptide derivatives of the tylosin family of macrolide antibiotics modified at the aldehyde group]. | 2010 Mar-Apr | Bioorg. Khim. | pmid:20531486 |
| Reynaldi FJ et al. | [Binding of tylosin, tilmicosin and oxytetracycline to proteins from honeybees, larvae and beehive products]. | 2010 Oct-Dec | Rev. Argent. Microbiol. | pmid:21229198 |
| Shimada T et al. | Effects of the antimicrobial tylosin on the microbial community structure of an anaerobic sequencing batch reactor. | 2011 | Biotechnol. Bioeng. | pmid:20830676 |
| Kim EY et al. | Pharmacokinetics of a florfenicol-tylosin combination after intravenous and intramuscular administration to beagle dogs. | 2011 | J. Vet. Med. Sci. | pmid:21068517 |
| Bosi P et al. | Feed supplemented with 3 different antibiotics improved food intake and decreased the activation of the humoral immune response in healthy weaned pigs but had differing effects on intestinal microbiota. | 2011 | J. Anim. Sci. | pmid:21724943 |
| Park JW et al. | Generation of reduced macrolide analogs by regio-specific biotransformation. | 2011 | J. Antibiot. | pmid:21102594 |
| Ci X et al. | Anti-inflammatory effects of tilmicosin in a noninfectious mouse model of allergic asthma. | 2011 | Immunopharmacol Immunotoxicol | pmid:21428709 |
| Zheng Y et al. | Molecularly imprinted solid-phase extraction for determination of tilmicosin in feed using high performance liquid chromatography. | 2011 | Anal. Chim. Acta | pmid:21435486 |
| Kalmokoff M et al. | Continuous feeding of antimicrobial growth promoters to commercial swine during the growing/finishing phase does not modify faecal community erythromycin resistance or community structure. | 2011 | J. Appl. Microbiol. | pmid:21395944 |
| Juntunen P et al. | Longitudinal on-farm study of the development of antimicrobial resistance in Campylobacter coli from pigs before and after danofloxacin and tylosin treatments. | 2011 | Vet. Microbiol. | pmid:21397412 |
| Cooprider KL et al. | Feedlot efficiency implications on greenhouse gas emissions and sustainability. | 2011 | J. Anim. Sci. | pmid:21398565 |
| Bernal J et al. | Determination of tylosins A, B, C and D in bee larvae by liquid chromatography coupled to ion trap-tandem mass spectrometry. | 2011 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:21498134 |
| Smee NM and Towell TL | What is the evidence? Inflammatory bowel disease in a dog. | 2011 | J. Am. Vet. Med. Assoc. | pmid:21529230 |
| Kilpinen S et al. | Effect of tylosin on dogs with suspected tylosin-responsive diarrhea: a placebo-controlled, randomized, double-blinded, prospective clinical trial. | 2011 | Acta Vet. Scand. | pmid:21489311 |
| Alexander TW et al. | Longitudinal characterization of antimicrobial resistance genes in feces shed from cattle fed different subtherapeutic antibiotics. | 2011 | BMC Microbiol. | pmid:21261985 |
| Ozaki H et al. | Antimicrobial resistance in fecal Escherichia coli isolated from growing chickens on commercial broiler farms. | 2011 | Vet. Microbiol. | pmid:21232883 |
| Song M et al. | The controlled release of tilmicosin from silica nanoparticles. | 2011 | Drug Dev Ind Pharm | pmid:21204738 |
| Stead SL et al. | Development and validation of a potentiometric biosensor assay for tylosin with demonstrated applicability for the detection of two other antimicrobial growth-promoter compounds in feedstuffs. | 2011 | Food Addit Contam Part A Chem Anal Control Expo Risk Assess | pmid:21574083 |
| Kucerova Z et al. | Antimicrobial susceptibility of Actinobacillus pleuropneumoniae isolates from clinical outbreaks of porcine respiratory diseases. | 2011 | Vet. Microbiol. | pmid:21316872 |
| Hidalgo à et al. | Trends towards lower antimicrobial susceptibility and characterization of acquired resistance among clinical isolates of Brachyspira hyodysenteriae in Spain. | 2011 | Antimicrob. Agents Chemother. | pmid:21555771 |
| Guan S et al. | Immunosuppressive activity of tilmicosin on the immune responses in mice. | 2011 | Immunopharmacol Immunotoxicol | pmid:20718577 |
| Lombardi KR et al. | Pharmacokinetics of tilmicosin in beef cattle following intravenous and subcutaneous administration. | 2011 | J. Vet. Pharmacol. Ther. | pmid:21323676 |
| Xie S et al. | Acute toxicity study of tilmicosin-loaded hydrogenated castor oil-solid lipid nanoparticles. | 2011 | Part Fibre Toxicol | pmid:22098626 |
| Danzeisen JL et al. | Modulations of the chicken cecal microbiome and metagenome in response to anticoccidial and growth promoter treatment. | 2011 | PLoS ONE | pmid:22114729 |
| Forrester CA et al. | Mycoplasma gallisepticum in pheasants and the efficacy of tylvalosin to treat the disease. | 2011 | Avian Pathol. | pmid:22107092 |
| Bohm DA et al. | Preparation and characterisation of in-house reference material of tylosin in honey and results of a proficiency test. | 2011 | Anal. Chim. Acta | pmid:21742117 |
| Dinh QT et al. | Measurement of trace levels of antibiotics in river water using on-line enrichment and triple-quadrupole LC-MS/MS. | 2011 | Talanta | pmid:21807177 |
| Gerchman I et al. | Characterization of in vivo-acquired resistance to macrolides of Mycoplasma gallisepticum strains isolated from poultry. | 2011 | Vet. Res. | pmid:21810258 |
| Ashenafi D et al. | An improved liquid chromatographic method for the analysis of tylosin and its impurities. | 2011 | J Sep Sci | pmid:21812113 |
| Chelliapan S et al. | Tolerance of the antibiotic tylosin on treatment performance of an up-flow anaerobic stage reactor (UASR). | 2011 | Water Sci. Technol. | pmid:21866757 |
| Stone JJ et al. | Land application of tylosin and chlortetracycline swine manure: Impacts to soil nutrients and soil microbial community structure. | 2011 | J Environ Sci Health B | pmid:21877979 |
| Han AR et al. | Biosynthesis of glycosylated derivatives of tylosin in Streptomyces venezuelae. | 2011 | J. Microbiol. Biotechnol. | pmid:21715968 |
| McClary DG et al. | Relationship of in vitro minimum inhibitory concentrations of tilmicosin against Mannheimia haemolytica and Pasteurella multocida and in vivo tilmicosin treatment outcome among calves with signs of bovine respiratory disease. | 2011 | J. Am. Vet. Med. Assoc. | pmid:21718206 |
| Lust EB et al. | Human health hazards of veterinary medications: information for emergency departments. | 2011 | J Emerg Med | pmid:20045604 |
| Poehlsgaard J et al. | Visualizing the 16-membered ring macrolides tildipirosin and tilmicosin bound to their ribosomal site. | 2012 | ACS Chem. Biol. | pmid:22563863 |
| Eguchi K et al. | Establishment of evaluation method to determine effects of veterinary medicinal products on manure fermentation using small-scale composting apparatus. | 2012 | J. Biosci. Bioeng. | pmid:22595343 |
| Pakpour S et al. | Frequency of antibiotic resistance in a swine facility 2.5 years after a ban on antibiotics. | 2012 | Microb. Ecol. | pmid:21997543 |
| Rérat M et al. | Bovine respiratory disease: efficacy of different prophylactic treatments in veal calves and antimicrobial resistance of isolated Pasteurellaceae. | 2012 | Prev. Vet. Med. | pmid:21945813 |
| Apley MD et al. | Use estimates of in-feed antimicrobials in swine production in the United States. | 2012 | Foodborne Pathog. Dis. | pmid:22324295 |
| Vandenberge V et al. | Transfer of flubendazole and tylosin from feed at cross-contamination levels to various poultry matrices. | 2012 | Poult. Sci. | pmid:22912473 |
| Andersen NM et al. | Inhibition of protein synthesis on the ribosome by tildipirosin compared with other veterinary macrolides. | 2012 | Antimicrob. Agents Chemother. | pmid:22926570 |
| Liu Y et al. | Transcriptional profiling of Haemophilus parasuis SH0165 response to tilmicosin. | 2012 | Microb. Drug Resist. | pmid:22935051 |
| Kim HB et al. | Microbial shifts in the swine distal gut in response to the treatment with antimicrobial growth promoter, tylosin. | 2012 | Proc. Natl. Acad. Sci. U.S.A. | pmid:22955886 |
| Menge M et al. | Pharmacokinetics of tildipirosin in bovine plasma, lung tissue, and bronchial fluid (from live, nonanesthetized cattle). | 2012 | J. Vet. Pharmacol. Ther. | pmid:22188102 |
| Granados-Chinchilla F et al. | A novel green chemistry method for nonaqueous extraction and high-performance liquid chromatography detection of first-, second-, and third-generation tetracyclines, 4-epitetracycline, and tylosin in animal feeds. | 2012 | J. Agric. Food Chem. | pmid:22738432 |
| Hagenbuch IM and Pinckney JL | Toxic effect of the combined antibiotics ciprofloxacin, lincomycin, and tylosin on two species of marine diatoms. | 2012 | Water Res. | pmid:22819871 |
| Devreese M et al. | Interaction between tylosin and bentonite clay from a pharmacokinetic perspective. | 2012 | Vet. J. | pmid:22749117 |
| Abutarbush SM et al. | Comparison of enrofloxacin and ceftiofur sodium for the treatment of relapse of undifferentiated fever/bovine respiratory disease in feedlot cattle. | 2012 | Can. Vet. J. | pmid:22753964 |
| Vandenberge V et al. | Transfer of flubendazole and tylosin at cross contamination levels in the feed to egg matrices and distribution between egg yolk and egg white. | 2012 | Poult. Sci. | pmid:22499885 |
| Persoons D et al. | Antimicrobial use in Belgian broiler production. | 2012 | Prev. Vet. Med. | pmid:22459488 |
| Kim HY et al. | Biochemical effects of veterinary antibiotics on proliferation and cell cycle arrest of human HEK293 cells. | 2012 | Bull Environ Contam Toxicol | pmid:22673765 |
| Blondeau JM et al. | Comparative minimum inhibitory and mutant prevention drug concentrations of enrofloxacin, ceftiofur, florfenicol, tilmicosin and tulathromycin against bovine clinical isolates of Mannheimia haemolytica. | 2012 | Vet. Microbiol. | pmid:22677482 |
| Sakai A et al. | Production of a hybrid 16-membered macrolide antibiotic by genetic engineering of Micromonospora sp. TPMA0041. | 2012 | J. Ind. Microbiol. Biotechnol. | pmid:22842988 |
| Srinivasan P et al. | Development of an HPLC method to analyze four veterinary antibiotics in soils and aqueous media and validation through fate studies. | 2012 | J Environ Sci Health A Tox Hazard Subst Environ Eng | pmid:22871010 |
| Er A and Yazar E | Effects of tylosin, tilmicosin and tulathromycin on inflammatory mediators in bronchoalveolar lavage fluid of lipopolysaccharide-induced lung injury. | 2012 | Acta Vet. Hung. | pmid:23160029 |
| Westermarck E and Wiberg M | Exocrine pancreatic insufficiency in the dog: historical background, diagnosis, and treatment. | 2012 | Top Companion Anim Med | pmid:23148848 |
| Peng D et al. | Development and validation of an indirect competitive enzyme-linked immunosorbent assay for the screening of tylosin and tilmicosin in muscle, liver, milk, honey and eggs. | 2012 | J. Agric. Food Chem. | pmid:22136611 |
| Kim KR et al. | Decline in extractable antibiotics in manure-based composts during composting. | 2012 | Waste Manag | pmid:21865024 |
| Wang XF et al. | Enhancement of antibacterial activity of tilmicosin against Staphylococcus aureus by solid lipid nanoparticles in vitro and in vivo. | 2012 | Vet. J. | pmid:21900026 |
| Del Pozo Sacristán R et al. | Efficacy of in-feed medication with chlortetracycline in a farrow-to-finish herd against a clinical outbreak of respiratory disease in fattening pigs. | 2012 Dec 22-29 | Vet. Rec. | pmid:23136309 |
| Jeong CY et al. | Effect of biochar amendment on tylosin adsorption-desorption and transport in two different soils. | 2012 Jul-Aug | J. Environ. Qual. | pmid:22751061 |
| Malaiyandi V et al. | Airborne allergic contact dermatitis from tylosin in pharmacy compounders and cross-sensitization to macrolide antibiotics. | 2012 Sep-Oct | Dermatitis | pmid:23010831 |
| Rose M et al. | Pharmacokinetics of tildipirosin in porcine plasma, lung tissue, and bronchial fluid and effects of test conditions on in vitro activity against reference strains and field isolates of Actinobacillus pleuropneumoniae. | 2013 | J. Vet. Pharmacol. Ther. | pmid:22500881 |
| Meyer NF et al. | Effects of monensin and tylosin in finishing diets containing corn wet distillers grains with solubles with differing corn processing methods. | 2013 | J. Anim. Sci. | pmid:23422007 |
| Garcés-Narro C et al. | Efficacy of low-dose tylvalosin for the control of clostridiosis in broilers and its effect on productive parameters. | 2013 | Poult. Sci. | pmid:23472021 |
| Mitchell JD et al. | In vitro pharmacodynamics of gamithromycin against Mycoplasma mycoides subspecies mycoides Small Colony. | 2013 | Vet. J. | pmid:23810743 |
| Chopra S et al. | Characterization of impurities in tylosin using dual liquid chromatography combined with ion trap mass spectrometry. | 2013 | Talanta | pmid:23598092 |
| Amachawadi RG et al. | Occurrence of the transferable copper resistance gene tcrB among fecal enterococci of U.S. feedlot cattle fed copper-supplemented diets. | 2013 | Appl. Environ. Microbiol. | pmid:23666328 |
| Whitehead TR and Cotta MA | Stored swine manure and swine faeces as reservoirs of antibiotic resistance genes. | 2013 | Lett. Appl. Microbiol. | pmid:23297734 |
| Hao H et al. | Mutational and transcriptomic changes involved in the development of macrolide resistance in Campylobacter jejuni. | 2013 | Antimicrob. Agents Chemother. | pmid:23274667 |
| Tsutsui A et al. | Antimalarial C-9 oxime derivatives from desmycosin, produced by click chemistry. | 2013 | J. Antibiot. | pmid:23232930 |
| Burkin MA and Galvidis IA | Hapten modification approach for switching immunoassay specificity from selective to generic. | 2013 | J. Immunol. Methods | pmid:23234756 |
| Holman DB and Chénier MR | Impact of subtherapeutic administration of tylosin and chlortetracycline on antimicrobial resistance in farrow-to-finish swine. | 2013 | FEMS Microbiol. Ecol. | pmid:23397987 |
| Ali M et al. | Effect of redox potential and pH status on degradation and adsorption behavior of tylosin in dairy lagoon sediment suspension. | 2013 | Chemosphere | pmid:23352520 |
| Gaudin V et al. | Validation of two ELISA kits for the screening of tylosin and streptomycin in honey according to the European decision 2002/657/EC. | 2013 | Food Addit Contam Part A Chem Anal Control Expo Risk Assess | pmid:23013044 |
| Devreese M et al. | An in vitro model using the IPEC-J2 cell line for efficacy and drug interaction testing of mycotoxin detoxifying agents. | 2013 | Toxicol In Vitro | pmid:23078954 |
| Pan R et al. | Extraction of trace tilmicosin in real water samples using ionic liquid-based aqueous two-phase systems. | 2013 | Water Sci. Technol. | pmid:23579819 |
| Zhang Q et al. | Sorption of tylosin on clay minerals. | 2013 | Chemosphere | pmid:24007614 |
| GarcÃa-Sánchez L et al. | Occurrence of tylosin in swine wastewater in Mexico. | 2013 | Water Sci. Technol. | pmid:23985521 |
| Svartström O et al. | Characterization of Treponema spp. isolates from pigs with ear necrosis and shoulder ulcers. | 2013 | Vet. Microbiol. | pmid:23948134 |
| Herd MB et al. | Extrasynaptic GABA(A) receptors couple presynaptic activity to postsynaptic inhibition in the somatosensory thalamus. | 2013 | J. Neurosci. | pmid:24027285 |
| Corns SM et al. | Development of antibiotic regimens using graph based evolutionary algorithms. | 2013 | BioSystems | pmid:24051263 |
| Stackhouse-Lawson KR et al. | Growth promoting technologies reduce greenhouse gas, alcohol, and ammonia emissions from feedlot cattle. | 2013 | J. Anim. Sci. | pmid:24085413 |
| Mitchell SM et al. | The effects of the antibiotics ampicillin, florfenicol, sulfamethazine, and tylosin on biogas production and their degradation efficiency during anaerobic digestion. | 2013 | Bioresour. Technol. | pmid:24113548 |
| Lin J et al. | Response of intestinal microbiota to antibiotic growth promoters in chickens. | 2013 | Foodborne Pathog. Dis. | pmid:23461609 |
| Shishkina A et al. | Conjugates of amino acids and peptides with 5-o-mycaminosyltylonolide and their interaction with the ribosomal exit tunnel. | 2013 | Bioconjug. Chem. | pmid:24090034 |
| Pinckney JL et al. | Sublethal effects of the antibiotic tylosin on estuarine benthic microalgal communities. | 2013 | Mar. Pollut. Bull. | pmid:23398744 |
| Pilcher CM et al. | Impact of tylosin phosphate and distillers dried grains with solubles on energy and nutrient digestibility and flow through the gastrointestinal tract in growing pigs. | 2013 | J. Anim. Sci. | pmid:24126274 |
| Maxwell CL et al. | Effects of beef production system on animal performance and carcass characteristics. | 2014 | J. Anim. Sci. | pmid:25403195 |
| Tennant TC et al. | Comparison of tulathromycin and tilmicosin on the prevalence and severity of bovine respiratory disease in feedlot cattle in association with feedlot performance, carcass characteristics, and economic factors. | 2014 | J. Anim. Sci. | pmid:25349362 |
| Holman DB and Chénier MR | Temporal changes and the effect of subtherapeutic concentrations of antibiotics in the gut microbiota of swine. | 2014 | FEMS Microbiol. Ecol. | pmid:25187398 |
| Avci T and Elmas M | Milk and blood pharmacokinetics of tylosin and tilmicosin following parenteral administrations to cows. | 2014 | ScientificWorldJournal | pmid:25177733 |
| Buß M et al. | Quality control ranges for tylosin 30 μg and 15 μg discs applicable to Staphylococcus aureus ATCC(R) 25923. | 2014 | J. Antimicrob. Chemother. | pmid:23928021 |
| Guo X et al. | The influences of pH and ionic strength on the sorption of tylosin on goethite. | 2014 | Environ Sci Pollut Res Int | pmid:24197966 |