| MeSH term | MeSH ID | Detail |
|---|---|---|
| Clostridium Infections | D003015 | 5 associated lipids |
| Pyoderma | D011711 | 5 associated lipids |
| Pneumonia, Mycoplasma | D011019 | 6 associated lipids |
| Liver Abscess | D008100 | 6 associated lipids |
| Mycoplasmatales Infections | D009180 | 6 associated lipids |
| Facial Dermatoses | D005148 | 7 associated lipids |
| Bacteriuria | D001437 | 7 associated lipids |
| Pasteurella Infections | D010326 | 8 associated lipids |
| Lymphadenitis | D008199 | 8 associated lipids |
| Staphylococcal Skin Infections | D013207 | 9 associated lipids |
Tylosin
Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Tylosin?
Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (6)
- Appl. Environ. Microbiol. (2)
- Proc. Natl. Acad. Sci. U.S.A. (2)
- Others (6)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Tylosin
PubChem Associated disorders and diseases
What pathways are associated with Tylosin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Tylosin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Tylosin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Tylosin?
There are no associated biomedical information in the current reference collection.
What genes are associated with Tylosin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (9)
- Microbiology (Reading, Engl.) (3)
- Proc. Natl. Acad. Sci. U.S.A. (2)
- Others (13)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Tylosin?
Knock-out
Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with Tylosin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Jacob ME et al. | Effects of feeding wet corn distillers grains with solubles with or without monensin and tylosin on the prevalence and antimicrobial susceptibilities of fecal foodborne pathogenic and commensal bacteria in feedlot cattle. | 2008 | J. Anim. Sci. | pmid:18192558 |
| Reuter RR et al. | Effects of dietary energy source and level and injection of tilmicosin phosphate on immune function in lipopolysaccharide-challenged beef steers. | 2008 | J. Anim. Sci. | pmid:18407986 |
| Samii SS et al. | Effects of limonene on ruminal concentrations, fermentation, and lysine degradation in cattle. | 2016 | J. Anim. Sci. | pmid:27695807 |
| Duff GC et al. | Effects of lasalocid and monensin plus tylosin on serum metabolic hormones and clinical chemistry profiles of beef steers fed a 90% concentrate diet. | 1994 | J. Anim. Sci. | pmid:8014140 |
| Ives SE et al. | Effects of virginiamycin and monensin plus tylosin on ruminal protein metabolism in steers fed corn-based finishing diets with or without wet corn gluten feed. | 2002 | J. Anim. Sci. | pmid:12462270 |
| Rozeboom DW et al. | Effects of mannan oligosaccharide and an antimicrobial product in nursery diets on performance of pigs reared on three different farms. | 2005 | J. Anim. Sci. | pmid:16230663 |
| Duff GC et al. | Effects of preshipping vs. arrival medication with tilmicosin phosphate and feeding chlortetracycline on health and performance of newly received beef cattle. | 2000 | J. Anim. Sci. | pmid:10709916 |
| Weinroth MD et al. | Rapid Communication: 16S ribosomal ribonucleic acid characterization of liver abscesses in feedlot cattle from three states in the United States. | 2017 | J. Anim. Sci. | pmid:29108068 |
| Mir PS et al. | Effects of dietary sunflower seeds and tylosin phosphate on production variables, carcass characteristics, fatty acid composition, and liver abscess incidence in crossbred steers. | 2008 | J. Anim. Sci. | pmid:18567724 |
| Chen J et al. | Technical note: Occurrence in fecal microbiota of genes conferring resistance to both macrolide-lincosamide-streptogramin B and tetracyclines concomitant with feeding of beef cattle with tylosin. | 2008 | J. Anim. Sci. | pmid:18469042 |
| Depenbusch BE et al. | Efficacy of monensin and tylosin in finishing diets based on steam-flaked corn with and without corn wet distillers grains with solubles. | 2008 | J. Anim. Sci. | pmid:18469059 |
| Chirase NK et al. | Effect of simulated ambient particulate matter exposure on performance, rectal temperature, and leukocytosis of young Spanish goats with or without tilmicosin phosphate. | 2004 | J. Anim. Sci. | pmid:15080345 |
| Müller HC et al. | Effects of intermittent feeding of tylosin phosphate during the finishing period on feedlot performance, carcass characteristics, antimicrobial resistance, and incidence and severity of liver abscesses in steers. | 2018 | J. Anim. Sci. | pmid:29718254 |
| Cooprider KL et al. | Feedlot efficiency implications on greenhouse gas emissions and sustainability. | 2011 | J. Anim. Sci. | pmid:21398565 |
| Nagaraja TG and Chengappa MM | Liver abscesses in feedlot cattle: a review. | 1998 | J. Anim. Sci. | pmid:9464910 |
| Meyer NF et al. | Effects of monensin and tylosin in finishing diets containing corn wet distillers grains with solubles with differing corn processing methods. | 2013 | J. Anim. Sci. | pmid:23422007 |
| Stackhouse-Lawson KR et al. | Growth promoting technologies reduce greenhouse gas, alcohol, and ammonia emissions from feedlot cattle. | 2013 | J. Anim. Sci. | pmid:24085413 |
| Hilton GG et al. | Effects of feeding zilpaterol hydrochloride with and without monensin and tylosin on carcass cutability and meat palatability of beef steers. | 2009 | J. Anim. Sci. | pmid:19028853 |
| Galyean ML et al. | Effects of arrival medication with tilmicosin phosphate on health and performance of newly received beef cattle. | 1995 | J. Anim. Sci. | pmid:7665351 |
| Clary EM et al. | Supplemental fat and ionophores in finishing diets: feedlot performance and ruminal digesta kinetics in steers. | 1993 | J. Anim. Sci. | pmid:8270535 |
| Amrine DE et al. | Pulmonary lesions and clinical disease response to Mannheimia haemolytica challenge 10 days following administration of tildipirosin or tulathromycin. | 2014 | J. Anim. Sci. | pmid:24243906 |
| Pilcher CM et al. | Impact of tylosin phosphate and distillers dried grains with solubles on energy and nutrient digestibility and flow through the gastrointestinal tract in growing pigs. | 2013 | J. Anim. Sci. | pmid:24126274 |
| Morris FE et al. | Effect of rotating monensin plus tylosin and lasalocid on performance, ruminal fermentation, and site and extent of digestion in feedlot cattle. | 1990 | J. Anim. Sci. | pmid:2254185 |
| Tan ZL et al. | Serum neutralizing antibodies against Fusobacterium necrophorum leukotoxin in cattle with experimentally induced or naturally developed hepatic abscesses. | 1994 | J. Anim. Sci. | pmid:8157537 |
| Lindemann MD et al. | Evaluation of antibiotic effects on phosphorus digestibility and utilization by growing-finishing pigs fed a phosphorus-deficient, corn-soybean meal diet. | 2010 | J. Anim. Sci. | pmid:20081078 |
| Brumm MC et al. | Effect of wean-to-finish management on pig performance. | 2002 | J. Anim. Sci. | pmid:11881920 |
| Brumm MC and Peo ER | Effect of receiving diets containing alfalfa and certain feed additives on performance of feeder pigs transported long distances. | 1985 | J. Anim. Sci. | pmid:4030523 |
| Potter EL et al. | Effect of monensin and tylosin on average daily gain, feed efficiency and liver abscess incidence in feedlot cattle. | 1985 | J. Anim. Sci. | pmid:4077750 |
| Day FG | The value of tilmicosin in production medicine. | 1996 | J. Am. Vet. Med. Assoc. | pmid:8617615 |
| Musser J et al. | Comparison of tilmicosin with long-acting oxytetracycline for treatment of respiratory tract disease in calves. | 1996 | J. Am. Vet. Med. Assoc. | pmid:8682696 |
| Veenhuizen MF et al. | Analysis of reports of human exposure to Micotil 300 (tilmicosin injection). | 2006 | J. Am. Vet. Med. Assoc. | pmid:17144818 |
| Morck DW et al. | Prophylactic efficacy of tilmicosin for bovine respiratory tract disease. | 1993 | J. Am. Vet. Med. Assoc. | pmid:8428833 |
| Smee NM and Towell TL | What is the evidence? Inflammatory bowel disease in a dog. | 2011 | J. Am. Vet. Med. Assoc. | pmid:21529230 |
| Smith GW et al. | Elimination kinetics of tilmicosin following intramammary administration in lactating dairy cattle. | 2009 | J. Am. Vet. Med. Assoc. | pmid:19210246 |
| Vogel GJ et al. | Effects of tilmicosin on acute undifferentiated respiratory tract disease in newly arrived feedlot cattle. | 1998 | J. Am. Vet. Med. Assoc. | pmid:9638194 |
| Alt DP et al. | Evaluation of antibiotics for treatment of cattle infected with Leptospira borgpetersenii serovar hardjo. | 2001 | J. Am. Vet. Med. Assoc. | pmid:11549093 |
| McClary DG et al. | Relationship of in vitro minimum inhibitory concentrations of tilmicosin against Mannheimia haemolytica and Pasteurella multocida and in vivo tilmicosin treatment outcome among calves with signs of bovine respiratory disease. | 2011 | J. Am. Vet. Med. Assoc. | pmid:21718206 |
| Lowell AN et al. | Chemoenzymatic Total Synthesis and Structural Diversification of Tylactone-Based Macrolide Antibiotics through Late-Stage Polyketide Assembly, Tailoring, and C-H Functionalization. | 2017 | J. Am. Chem. Soc. | pmid:28525276 |
| Castonguay R et al. | Stereospecificity of ketoreductase domains 1 and 2 of the tylactone modular polyketide synthase. | 2008 | J. Am. Chem. Soc. | pmid:18693734 |
| Wang J et al. | Determination of five macrolide antibiotic residues in eggs using liquid chromatography/electrospray ionization tandem mass spectrometry. | 2005 | J. Agric. Food Chem. | pmid:15769104 |
| Blackwell PA et al. | Evaluation of a lower tier exposure assessment model for veterinary medicines. | 2005 | J. Agric. Food Chem. | pmid:15769156 |
| Beier RC et al. | Production and characterization of monoclonal antibodies against the antibiotic tilmicosin. | 2005 | J. Agric. Food Chem. | pmid:16332115 |
| Peng Z and Bang-Ce Y | Small molecule microarrays for drug residue detection in foodstuffs. | 2006 | J. Agric. Food Chem. | pmid:16968051 |
| Jiang H et al. | Residue depletion of tilmicosin in cattle after subcutaneous administration. | 2006 | J. Agric. Food Chem. | pmid:16819937 |
| Caldow M et al. | Development and validation of an optical SPR biosensor assay for tylosin residues in honey. | 2005 | J. Agric. Food Chem. | pmid:16159159 |
| Zhang Y et al. | Residue depletion of tilmicosin in chicken tissues. | 2004 | J. Agric. Food Chem. | pmid:15113165 |
| Wang J | Determination of five macrolide antibiotic residues in honey by LC-ESI-MS and LC-ESI-MS/MS. | 2004 | J. Agric. Food Chem. | pmid:14733491 |
| Granados-Chinchilla F et al. | A novel green chemistry method for nonaqueous extraction and high-performance liquid chromatography detection of first-, second-, and third-generation tetracyclines, 4-epitetracycline, and tylosin in animal feeds. | 2012 | J. Agric. Food Chem. | pmid:22738432 |
| Peng D et al. | Development and validation of an indirect competitive enzyme-linked immunosorbent assay for the screening of tylosin and tilmicosin in muscle, liver, milk, honey and eggs. | 2012 | J. Agric. Food Chem. | pmid:22136611 |
| Werner JJ et al. | Environmental photochemistry of tylosin: efficient, reversible photoisomerization to a less-active isomer, followed by photolysis. | 2007 | J. Agric. Food Chem. | pmid:17655244 |